在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HECW1 Antibody

HECW1 Antibody

  • 中文名稱：
    HECW1兔多克隆抗體
  • 貨號：
    CSB-PA748484HA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of A549 cells with CSB-PA748484HA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HECW1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HECW1
  • 別名：
    C2 and WW domain-containing protein 1 antibody; E3 ubiquitin-protein ligase HECW1 antibody; HECT antibody; HECT type E3 ubiquitin ligase antibody; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antibody; HECT, C2 and WW domain-containing protein 1 antibody; HECW 1 antibody; Hecw1 antibody; HECW1_HUMAN antibody; hNEDL1 antibody; NEDD4 like ubiquitin protein ligase 1 antibody; NEDD4-like E3 ubiquitin-protein ligase 1 antibody; NEDL1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase HECW1 protein (751-900AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，HECW1 Antibody (CSB-PA748484HA01HU)，的標記方式是Non-conjugated。對于HECW1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA748484HB01HU HECW1 Antibody, HRP conjugated ELISA
    FITC CSB-PA748484HC01HU HECW1 Antibody, FITC conjugated
    Biotin CSB-PA748484HD01HU HECW1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
  • 基因功能參考文獻：
    1. Ndel1 acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly. PMID: 26880200
    2. Ndel1 regulates Dyn2 GTPase activity and impacts GluR1-containing membranes distribution in a manner reminiscent of Dyn2. PMID: 21283621
    3. These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength. PMID: 20976258
    4. These findings suggest that RNF43 is associated with p53-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis. PMID: 21108931
    5. interaction among misfolded SOD1, NEDL1, translocon-associated protein-delta, and Dishevelled-1 forms a ubiquitinated protein complex that is included in potentially cytotoxic protein aggregates PMID: 14684739
    6. functional interaction of NEDL1 with p53 might contribute to the induction of apoptosis in cancerous cells bearing wild-type p53. PMID: 18223681

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 組織特異性：
    Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 22195

    OMIM: 610384

    KEGG: hsa:23072

    STRING: 9606.ENSP00000379228

    UniGene: Hs.164453



主站蜘蛛池模板： 欧美一区二区三区啪啪| 中文日韩亚洲欧美制服 | 国产ktv交换配乱婬视频| 少妇午夜av一区| 领导边摸边吃奶边做爽在线观看| 国产成人精品男人的天堂| 国产亚洲欧美另类一区二区 | 亚洲午夜成人精品无码app| 一本aⅴ高清一区二区三区| 久久综合婷婷丁香五月中文字幕 | 老太脱裤让老头玩ⅹxxxx| 一二三区乱码不卡手机版| 亚洲国产精品久久久久爰| 亚洲精品久久婷婷丁香51| 18禁止看的免费污网站| 色丁香婷婷综合久久| 亚洲精品无码久久千人斩| 中文字幕亚洲综合久久综合| 国产午夜无码福利在线看网站| 少妇被躁爽到高潮无码文| 国产精品免费观看久久| 日韩欧无码一二三区免费不卡 | 久久97久久97精品免视看秋霞| 午夜嘿嘿嘿影院| 俄罗斯丰满熟妇hd| 天堂资源中文最新版在线一区| 77se77亚洲欧美在线| 无码抽搐高潮喷水流白浆| 中文无码乱人伦中文视频在线v| 国产精品对白交换视频| 久久精品2021国产| 国产超碰人人做人人爽av动图| 免费无码午夜理论电影| 高清不卡一区二区三区| 无码精品国产一区二区三区免费| 少妇夜夜春夜夜爽试看视频| 国产拍揄自揄精品视频| 中文在线8资源库| 又色又爽又高潮免费视频国产| 亚洲日韩穿丝袜在线推荐| 欧洲av无码放荡人妇网站|