在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HECW1 Antibody, FITC conjugated

HECW1 Antibody, FITC conjugated

  • 中文名稱：
    HECW1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA748484HC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HECW1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HECW1
  • 別名：
    C2 and WW domain-containing protein 1 antibody; E3 ubiquitin-protein ligase HECW1 antibody; HECT antibody; HECT type E3 ubiquitin ligase antibody; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antibody; HECT, C2 and WW domain-containing protein 1 antibody; HECW 1 antibody; Hecw1 antibody; HECW1_HUMAN antibody; hNEDL1 antibody; NEDD4 like ubiquitin protein ligase 1 antibody; NEDD4-like E3 ubiquitin-protein ligase 1 antibody; NEDL1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase HECW1 protein (751-900AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
  • 基因功能參考文獻：
    1. Ndel1 acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly. PMID: 26880200
    2. Ndel1 regulates Dyn2 GTPase activity and impacts GluR1-containing membranes distribution in a manner reminiscent of Dyn2. PMID: 21283621
    3. These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength. PMID: 20976258
    4. These findings suggest that RNF43 is associated with p53-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis. PMID: 21108931
    5. interaction among misfolded SOD1, NEDL1, translocon-associated protein-delta, and Dishevelled-1 forms a ubiquitinated protein complex that is included in potentially cytotoxic protein aggregates PMID: 14684739
    6. functional interaction of NEDL1 with p53 might contribute to the induction of apoptosis in cancerous cells bearing wild-type p53. PMID: 18223681

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 組織特異性：
    Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 22195

    OMIM: 610384

    KEGG: hsa:23072

    STRING: 9606.ENSP00000379228

    UniGene: Hs.164453



主站蜘蛛池模板： 高潮喷水无码av亚洲| 图片区小说区av区| 99er热精品视频| 免费裸体美女网站| 国产超碰人人爽人人做| 中文韩国午夜理伦三级好看| 日日婷婷夜日日天干| 久久只有这里有精品4| 久久久久久久精品成人热色戒汤唯 | 亚洲精品1卡2卡三卡4卡乱码| 国产亚洲精品一区在线播放| 884aa四虎影成人精品| 性欧美暴力猛交69hd| 国产成人精品综合久久久久| 青青久在线视观看视| 手机看片精品国产福利| 亚洲一卡二卡三卡四卡无卡麻豆| 香港三级精品三级在线专区| 国产成人小视频| 99久久久无码国产精品动漫| 久久久久国色av∨免费看| 图片区 小说区 区 亚洲五月 | 99久热re在线精品视频| 久久精品中文字幕有码| 久久棈精品久久久久久噜噜| 国内少妇偷人精品免费| 亚洲欧美成人久久一区| 色综合伊人丁香五月桃花婷婷| 亚洲精品天堂成人片av在线播放 | 内射视频←www夜| 国产性色播播毛片| 九九久久精品国产av片国产| www亚洲精品久久久乳| 又黄又爽又色的免费网站| 欧美真人做爰在线观看| 亚洲成a人v影院色老汉影院| 免费午夜无码片在线观看影院 | 天天摸天天做天天爽水多| 天天色影网| 精品无人区码一码二码三码区别| 欧洲美女熟乱av|