在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GM2A Antibody, HRP conjugated

GM2A Antibody, HRP conjugated

  • 中文名稱：
    GM2A兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA02375B0Rb
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GM2A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GM2A
  • 別名：
    Cerebroside sulfate activator protein antibody; ganglioside GM2 activator antibody; Ganglioside GM2 activator isoform short antibody; Ganglioside GM2 activator precursor antibody; GM2 activator antibody; GM2 AP antibody; GM2 ganglioside activator antibody; GM2 ganglioside activator protein antibody; GM2-AP antibody; GM2A antibody; GM2AP antibody; OTTHUMP00000160619 antibody; SAP 3 antibody; SAP-3 antibody; SAP3 antibody; SAP3_HUMAN antibody; Shingolipid activator protein 3 antibody; Sphingolipid activator protein 3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ganglioside GM2 activator protein (32-193AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity. Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Has cholesterol transfer activity.
  • 基因功能參考文獻(xiàn)：
    1. Review of GM2A mutations causing GM2 activator protein deficiency and GM2 gangliosidosis-AB variant. PMID: 27402091
    2. Studies indicate that sphingolipid activator proteins (SAPs) and anionic lipids are essential stimulators to reach physiological rates of lysosomal sphingolipid degradation. PMID: 27157270
    3. this study has established the potential role of GM2A in breast cancer progression PMID: 27002480
    4. Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies PMID: 26175473
    5. Gene polymorphisms of MD2 and GM2A were associated with the occurrence or severity of neonatal necrotizing enterocolitis. PMID: 25816011
    6. In vitro assays with the isolated H1 or H2 homodimers (beta-alpha hybrid construct of beta-hexosaminidase A subunits) confirmed that neither was capable of human GM2AP-dependent hydrolysis of GM2 ganglioside. PMID: 23483939
    7. impact of GM2AP on glucose metabolism PMID: 21784073
    8. Treatment of meniscal explants with IL-1RA inhibited the expression of many catabolic genes following a single bout of high dynamic strain. PMID: 21331553
    9. these results provide novel insights into the physiological functions of GM2AP in obesity. PMID: 21036149
    10. GM2 activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D PMID: 12576516
    11. Two new structures of GM2-AP with bound lipids, showing two different lipid-binding modes within the apolar pocket PMID: 12909021
    12. elucidation of mode of action on gangioside GM2 PMID: 14728689
    13. alpha-subunit loop structure is required for GM2 activator protein binding by beta-hexosaminidase A PMID: 15485660
    14. glycosphingolipids, particularly GM2, form a complex with CD82, and this complex interacts with Met and thereby inhibits HGF-induced Met tyrosine kinase activity, as well as integrin to Met cross-talk PMID: 17215249

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    GM2-gangliosidosis AB (GM2GAB)
  • 亞細(xì)胞定位：
    Lysosome.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4367

    OMIM: 272750

    KEGG: hsa:2760

    STRING: 9606.ENSP00000349687

    UniGene: Hs.483873



主站蜘蛛池模板： 高清国产在线拍揄自揄视频| 亚洲国产精品尤物yw在线| 西西人体大胆扒开下部337卩| 亚洲欧美日韩另类精品一区| 性xxxx18免费观看视频| 98国产精品综合一区二区三区| 人妻熟女一区二区aⅴ图片| 52综合精品国产二区无码| 国产偷v国产偷v亚洲高清| 国产尤物精品视频| 国产亚洲中文日韩欧美综合网| 亚洲中文字幕国产综合| 亚洲小说春色综合另类| 无尺码精品产品日韩| 一区二区三区高清日本vr| 在线观看国产丝袜控网站 | 熟女少妇人妻黑人sirbao| 国产精品卡一卡2卡3卡4| 成人三级视频在线观看一区二区| 无码人妻一区二区三区免费看成人| 337p粉嫩日本欧洲亚洲大胆| 亚洲人成人无码www| 岛国在线无码高清视频| 国产乱人伦精品一区二区在线观看 | 欧美极品少妇性运交| 国产 av 仑乱内谢| 黑人巨大av无码专区| 五月av综合av国产av| 性生交大片免费看l| 久久亚洲精品国产精品婷婷| 国产精品禁18久久久夂久| 亚洲a∨国产av综合av下载| 国精品人妻无码一区二区三区d3 | 国产制服丝袜欧美在线观看| 成人试看120秒体验区| 最爽无遮挡行房视频| 狠狠躁夜夜躁无码中文字幕| 国产成人一区二区三区app| 男女猛烈xx00免费视频试看| 国产69精品久久久久人妻刘玥| 国语自产拍在线视频中文|