在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GALK1 Antibody

  • 中文名稱:
    GALK1兔多克隆抗體
  • 貨號:
    CSB-PA002637
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HeLa cells using GALK1 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GALK1
  • 別名:
    EC 2.7.1.6 antibody; epididymis secretory protein Li 19 antibody; Galactokinase 1 antibody; Galactokinase antibody; Galactose kinase antibody; GALK 1 antibody; GALK antibody; GALK1 antibody; GALK1_HUMAN antibody; GK1 antibody; GLK antibody; GLK1 antibody; HEL-S-19 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human GALK1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Major enzyme for galactose metabolism.
  • 基因功能參考文獻:
    1. Mutation in the GALK gene is associated with mental disorders in galactosemia. PMID: 28672748
    2. The GALK1 gene was included in this interval and direct sequencing. PMID: 24211322
    3. Data indicate taht the interactions between galactokinase (GALK) and its potential inhibitors by molecular dynamics simulations. PMID: 23517731
    4. The study highlighted the importance of GALK gene analysis in diagnosis of galactosemia in Indian population. PMID: 22632133
    5. A possible mechanism for the unfolding caused by the Pro(28)Thr point mutation of human galactokinase. PMID: 21264483
    6. Pathogenic mutations in GALK1 that are responsible for autosomal recessive congenital cataracts in consanguineous Pakistani families, are reported. PMID: 20405025
    7. 2 new GALK1 mutations near the ATP-binding site were found in a homozygotic Turkish immigrant: S142I and G148C. PMID: 11978883
    8. a functional analysis of disease-causing mutations in this enzyme PMID: 12694189
    9. In this northern Italian population age-related cataract does not appear to be associated with GALK1 alleles. PMID: 12942049
    10. structure and function of galactokinase, and role in type II galactosemia [review] PMID: 15526155
    11. active site geometry of this enzyme upon which to more fully understand the consequences of the those mutations known to give rise to Type II galactosemia. PMID: 15590630
    12. Mutations in GALK1 resulted in reduction of GALK activity and caused GALK deficiency. PMID: 17517531
    13. These results suggest that the elevated GALK1 activity resulted from enhanced gene expression, due to nucleotide variation within GALK1 promoter PMID: 19309526
    14. Structure of the human enzyme complexed with MgAMP.PNP and galactose PMID: 15590630
    15. The disease-causing point mutations in the human enzyme are mapped onto the structure of the protein from Pyrococcus furiosus and speculations made about the structural consequences. PMID: 15003454
    16. 2-deoxy-D-galactose is a substrate for this enzyme. D-glucose, D-fucose, L-arabinose and N-acetyl-D-galactosamine are not. Mutations H44A, H44I, E43G/H44I are insoluble, D46A is inactive, E43G has reduced activity and E43A has wild-type activity. PMID: 14596685
    17. Has ordered ternary complex mechanism with ATP being the first substrate to bind. PMID: 12694189

    顯示更多

    收起更多

  • 相關疾病:
    Galactosemia II (GALCT2)
  • 蛋白家族:
    GHMP kinase family, GalK subfamily
  • 數據庫鏈接:

    HGNC: 4118

    OMIM: 230200

    KEGG: hsa:2584

    STRING: 9606.ENSP00000225614

    UniGene: Hs.407966



主站蜘蛛池模板: 国内精品久久久久久久97牛牛| 人妻熟女av一区二区三区| 天天躁日日躁狠狠躁性色av| 99久久国产综合精品五月天喷水 | 亚洲处破女av日韩精品波波网| 无码国产精成人午夜视频| 久久久久久久久毛片精品| 亚洲成a人片77777kkkk| 538prom精品视频在线播放| 亚洲精品久久国产精品| 成人乱码一区二区三区av| 国产欧美日韩精品a在线观看| 久久久久99精品成人片牛牛影视| 成 人影片 免费观看在线| 999久久久免费精品国产| 欧美巨大另类极品videosbest| 亚洲欧美日韩国产综合v| 内谢少妇xxxxx8老少交| 国产乱人伦精品免费| 天天爽天天爽天天爽| 伊人精品一本久久综合| 亚洲熟妇av综合网五月| 欧美日韩一区二区综合| 西西人体大胆午夜啪啪| 草裙社区精品视频三区免费看 | 男阳茎进女阳道视频大全 | 露脸内射熟女--69xx| 少妇饥渴xxhd麻豆xxhd骆驼| 香蕉精品亚洲二区在线观看 | 亚洲日本va中文字幕亚洲| 免费久久99精品国产自在现线 | 国产 | 欧洲野花视频欧洲1| 国产卡一卡二卡三精品| 人人妻人人澡人人爽| 亚洲伊人久久大香线蕉综合图片| 亚洲国产精品无码久久一区二区| 国产精品99久久久久久久女警| 久久国产色av免费看| 日本看片一二三区高清| 亚洲成a人片在线观看日本| 噜妇插内射精品|