在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GALK1 Antibody

  • 中文名稱:
    GALK1兔多克隆抗體
  • 貨號:
    CSB-PA009198GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GALK1
  • 別名:
    EC 2.7.1.6 antibody; epididymis secretory protein Li 19 antibody; Galactokinase 1 antibody; Galactokinase antibody; Galactose kinase antibody; GALK 1 antibody; GALK antibody; GALK1 antibody; GALK1_HUMAN antibody; GK1 antibody; GLK antibody; GLK1 antibody; HEL-S-19 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human GALK1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Major enzyme for galactose metabolism.
  • 基因功能參考文獻:
    1. Mutation in the GALK gene is associated with mental disorders in galactosemia. PMID: 28672748
    2. The GALK1 gene was included in this interval and direct sequencing. PMID: 24211322
    3. Data indicate taht the interactions between galactokinase (GALK) and its potential inhibitors by molecular dynamics simulations. PMID: 23517731
    4. The study highlighted the importance of GALK gene analysis in diagnosis of galactosemia in Indian population. PMID: 22632133
    5. A possible mechanism for the unfolding caused by the Pro(28)Thr point mutation of human galactokinase. PMID: 21264483
    6. Pathogenic mutations in GALK1 that are responsible for autosomal recessive congenital cataracts in consanguineous Pakistani families, are reported. PMID: 20405025
    7. 2 new GALK1 mutations near the ATP-binding site were found in a homozygotic Turkish immigrant: S142I and G148C. PMID: 11978883
    8. a functional analysis of disease-causing mutations in this enzyme PMID: 12694189
    9. In this northern Italian population age-related cataract does not appear to be associated with GALK1 alleles. PMID: 12942049
    10. structure and function of galactokinase, and role in type II galactosemia [review] PMID: 15526155
    11. active site geometry of this enzyme upon which to more fully understand the consequences of the those mutations known to give rise to Type II galactosemia. PMID: 15590630
    12. Mutations in GALK1 resulted in reduction of GALK activity and caused GALK deficiency. PMID: 17517531
    13. These results suggest that the elevated GALK1 activity resulted from enhanced gene expression, due to nucleotide variation within GALK1 promoter PMID: 19309526
    14. Structure of the human enzyme complexed with MgAMP.PNP and galactose PMID: 15590630
    15. The disease-causing point mutations in the human enzyme are mapped onto the structure of the protein from Pyrococcus furiosus and speculations made about the structural consequences. PMID: 15003454
    16. 2-deoxy-D-galactose is a substrate for this enzyme. D-glucose, D-fucose, L-arabinose and N-acetyl-D-galactosamine are not. Mutations H44A, H44I, E43G/H44I are insoluble, D46A is inactive, E43G has reduced activity and E43A has wild-type activity. PMID: 14596685
    17. Has ordered ternary complex mechanism with ATP being the first substrate to bind. PMID: 12694189

    顯示更多

    收起更多

  • 相關疾病:
    Galactosemia II (GALCT2)
  • 蛋白家族:
    GHMP kinase family, GalK subfamily
  • 數據庫鏈接:

    HGNC: 4118

    OMIM: 230200

    KEGG: hsa:2584

    STRING: 9606.ENSP00000225614

    UniGene: Hs.407966



主站蜘蛛池模板: 自拍偷自拍亚洲精品被多人伦好爽| 精品多人p群无码| 亚洲乱码卡一卡二卡新区仙踪木木 | 欲色影视天天一区二区三区色香欲| 久久无码超清激情av| 日本乱码伦午夜福利在线| 女女互磨互喷水高潮les呻吟| 影音先锋男人站| 精品成人a区在线观看| 欧美精品videosbestsex日本| 激情综合色五月丁香六月亚洲| 久久久久国产综合av天堂| 日本在线看片免费人成视频| 久久九九精品国产av片国产| 午夜福利精品导航凹凸| 麻豆高清免费国产一区| 国产jjzzjjzz视频全部免费| 亚洲国产老鸭窝一区二区三区| 精品少妇人妻av免费久久洗澡| 欧美国产国产综合视频| 国产真实偷乱视频| 丁香五月网久久综合| 波多野结衣av在线观看| 国产精品久久..4399| 亚洲精品久久久久久成人 | 免费的av网站手机版| 国产精品第一国产精品| 亚洲欧美日本久久综合网站| 美女又大又黄www免费网站| 精品国产三级a∨在线欧美| 日本中国内射bbxx| 麻豆av字幕无码中文| 国产99视频精品免费观看9| 日韩精品一区二区三区视频| 国产日产欧产美| 婷婷四虎东京热无码群交双飞视频| 亚洲国产精品久久久久久久| 欧美三级不卡在线观看| 真实国产精品vr专区| 久久精品99国产精品日本| 欧美老熟妇乱大交xxxxx|