在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FUNDC1 Antibody

FUNDC1 Antibody

  • 中文名稱：
    FUNDC1兔多克隆抗體
  • 貨號：
    CSB-PA006338
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of AD293 cells using FUNDC1 Polyclonal Antibody
    • Western Blot analysis of AD293 cells using FUNDC1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    FUNDC1; FUN14 domain-containing protein 1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human FUNDC1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
  • 基因功能參考文獻：
    1. Our data suggested that FUNDC1 can be used as a prognostic biomarker in patients with cervical cancer, and may be a new therapeutic target to improve the antitumor effects of chemoradiotherapy. PMID: 28719148
    2. phosphorylation of Tyr18 of FUNDC1 serves as a molecular switch for mitophagy. PMID: 27653272
    3. FUNDC1 integrates mitochondrial fission and mitophagy at the interface of the endoplasmic reticulum-mitochondrial contact site by working in concert with DRP1 and calnexin under hypoxic conditions in mammalian cells. PMID: 27145933
    4. FUNDC1 regulates both mitochondrial fission or fusion and mitophagy. PMID: 27050458
    5. The BCL2L1-PGAM5-FUNDC1 axis is critical for receptor-mediated mitophagy. PMID: 25126723
    6. FUNDC1 regulates ULK1 recruitment to damaged mitochondria, where FUNDC1 phosphorylation by ULK1 is crucial for mitophagy. PMID: 24671035
    7. Data show that Knockdown of endogenous FUNDC1 significantly prevented hypoxia-induced mitophagy, which could be reversed by the expression of wild-type FUNDC1. PMID: 22267086

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    FUN14 family
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 28746

    OMIM: 300871

    KEGG: hsa:139341

    STRING: 9606.ENSP00000367284

    UniGene: Hs.7549



主站蜘蛛池模板： 六十熟妇乱子伦视频| 国产精品无码无在线观看| 欧美96在线 | 欧| 草草影院精品一区二区三区| 最近最好的中文字幕2019免费| 欧美乱码卡一卡二卡四卡免费| 中文字幕精品一二三四五六七八| 亚洲大尺度无码专区尤物| 中文乱码字慕人妻熟女人妻 | 欧美牲交a欧美牲交| 无码一区二区三区av免费| 国产精品亚洲五月天高清| 校花高潮抽搐冒白浆| 丰满岳妇乱一区二区三区| 国产一线二线三线女| 欧美国产日韩a在线视频| 久久亚洲道色宗和久久| 中文字幕av无码一二三区电影| 国产又色又爽又刺激在线播放| 无码人妻精品一区二区蜜桃百度| 极品人妻被黑人中出种子| 国产三级aⅴ在在线观看| 丰满少妇呻吟高潮经历| 亚洲精品国产suv一区| 男女啪祼交视频| 国产揉捏爆乳巨胸挤奶视频| 奇米777四色成人影视| 亚洲精品午夜国产va久久成人| 人妻丰满熟妞av无码区| 成人爽a毛片免费网站| 国产午夜精品一二区理论影院| 亚洲日韩av无码| 久久久久噜噜噜亚洲熟女综合| 久久精品国产精油按摩| 亚洲成a∧人片在线播放调教| 国产成人a亚洲精v品无码| 阳茎伸入女人阳道视频| 男人和女人高潮做爰视频| 欧美熟妇性xxx交潮喷| 老熟女 露脸 嗷嗷叫| 久久青青草原国产精品最新片 |