在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FUNDC1 Antibody, FITC conjugated

FUNDC1 Antibody, FITC conjugated

  • 中文名稱：
    FUNDC1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA816886LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FUNDC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    FUNDC1; FUN14 domain-containing protein 1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human FUN14 domain-containing protein 1 protein (1-46AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
  • 基因功能參考文獻：
    1. Our data suggested that FUNDC1 can be used as a prognostic biomarker in patients with cervical cancer, and may be a new therapeutic target to improve the antitumor effects of chemoradiotherapy. PMID: 28719148
    2. phosphorylation of Tyr18 of FUNDC1 serves as a molecular switch for mitophagy. PMID: 27653272
    3. FUNDC1 integrates mitochondrial fission and mitophagy at the interface of the endoplasmic reticulum-mitochondrial contact site by working in concert with DRP1 and calnexin under hypoxic conditions in mammalian cells. PMID: 27145933
    4. FUNDC1 regulates both mitochondrial fission or fusion and mitophagy. PMID: 27050458
    5. The BCL2L1-PGAM5-FUNDC1 axis is critical for receptor-mediated mitophagy. PMID: 25126723
    6. FUNDC1 regulates ULK1 recruitment to damaged mitochondria, where FUNDC1 phosphorylation by ULK1 is crucial for mitophagy. PMID: 24671035
    7. Data show that Knockdown of endogenous FUNDC1 significantly prevented hypoxia-induced mitophagy, which could be reversed by the expression of wild-type FUNDC1. PMID: 22267086

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    FUN14 family
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 28746

    OMIM: 300871

    KEGG: hsa:139341

    STRING: 9606.ENSP00000367284

    UniGene: Hs.7549



主站蜘蛛池模板： 亚洲国产制服丝袜高清在线| 国产精品自产拍高潮在线观看| 好吊色欧美一区二区三区视频| 97香蕉碰碰人妻国产欧美| 国产日产欧洲无码视频| 精品亚洲国产成人蜜臀优播av| 久久婷婷狠狠综合激情| 无码视频免费一区二区三区| 色在线 | 国产| 老司机亚洲精品影院无码| 成人无遮羞视频在线观看| 日韩av爽爽爽久久久久久| av国産精品毛片一区二区视频| 国产伦精品一区二区三区妓女| 夜夜未满十八勿进的爽爽影院| 亚洲 欧美 另类图片| 亚洲国产精品va在线观看麻豆| 妺妺窝人体色www在线观看| 99久热在线精品996热是什么| 大肉大捧一进一出好爽mba| 久久超碰精品一夜七次郎| 国产饥渴孕妇在线播放| 亚洲a无码综合a国产av中文 | 午夜影视免费| 黑人大荫蒂高潮视频| 电影内射视频免费观看| 国产精品三级av三级av三级| 四虎永久在线精品免费网站 | 一区二区三区国产亚洲网站| 日本国产网曝视频在线观看| 亚洲精品伊人久久久大香 | 亚洲精品无码av人在线观看国产| 亚洲一区二区三区四区五区六区 | 男人用嘴添女人私密视频| 蜜臀性色av免费| 国产精品99久久久久久宅男小说| 欧美疯狂做受xxxx高潮| 精品久久久久久亚洲精品 | 大伊香蕉精品一区二区| 日韩欧美在线综合网| 国产成人综合久久三区|