在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FUNDC1 Antibody, HRP conjugated

  • 中文名稱:
    FUNDC1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA816886LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FUNDC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FUNDC1; FUN14 domain-containing protein 1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human FUN14 domain-containing protein 1 protein (1-46AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
  • 基因功能參考文獻:
    1. Our data suggested that FUNDC1 can be used as a prognostic biomarker in patients with cervical cancer, and may be a new therapeutic target to improve the antitumor effects of chemoradiotherapy. PMID: 28719148
    2. phosphorylation of Tyr18 of FUNDC1 serves as a molecular switch for mitophagy. PMID: 27653272
    3. FUNDC1 integrates mitochondrial fission and mitophagy at the interface of the endoplasmic reticulum-mitochondrial contact site by working in concert with DRP1 and calnexin under hypoxic conditions in mammalian cells. PMID: 27145933
    4. FUNDC1 regulates both mitochondrial fission or fusion and mitophagy. PMID: 27050458
    5. The BCL2L1-PGAM5-FUNDC1 axis is critical for receptor-mediated mitophagy. PMID: 25126723
    6. FUNDC1 regulates ULK1 recruitment to damaged mitochondria, where FUNDC1 phosphorylation by ULK1 is crucial for mitophagy. PMID: 24671035
    7. Data show that Knockdown of endogenous FUNDC1 significantly prevented hypoxia-induced mitophagy, which could be reversed by the expression of wild-type FUNDC1. PMID: 22267086

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族:
    FUN14 family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 28746

    OMIM: 300871

    KEGG: hsa:139341

    STRING: 9606.ENSP00000367284

    UniGene: Hs.7549



主站蜘蛛池模板: 国产人妻aⅴ色偷| 欧美午夜一区二区福利视频| 欧美日韩一区二区综合| 精品国产乱码久久久久久影片| 少妇无码av无码专区线| 久久永久免费专区人妻精品| 国产精品 中文字幕 亚洲 欧美 | 欧美 国产 日产 韩国 在线| 女人被狂c到高潮视频网站| 97精品免费公开在线视频| 国产亚洲精aa在线观看| 国产成人精品无码免费看| 无码av一区二区三区无码| 国产亚洲日韩欧美另类第八页| 中文字幕三级人妻无码视频| 亚洲综合电影小说图片区| 麻花豆传媒剧国产免费mv观看| 中文字幕精品久久久久人妻红杏1| 精品国产一区av天美传媒| 伊人无码精品久久一区二区 | 国语自产拍在线视频中文| 国产成人午夜在线视频a站| 成人午夜福利视频| 超清中文乱码字幕在线观看| 亚洲国产综合av在线观看| 亚洲综合无码av一区二区三区| 久久av高潮av无码av喷吹| 国产精品www夜色视频| 青青草无码伊人久久| 国产亚洲色欲色一色www| 国产成人无码aa精品一区| 国产成人精品一区二三区在线观看| 四虎国产精品永久入口| 国产精品亚洲综合色区| 伊人色合天天久久综合网| 精产国品一二三产区m553麻豆| 曰韩少妇内射免费播放| 成年轻人电影免费无码| 国产超碰人人做人人爱| 欧美性大战久久久久xxx| 国产999精品久久久久久|