在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FANCF Antibody

  • 中文名稱:
    FANCF兔多克隆抗體
  • 貨號:
    CSB-PA873614LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate, K562 whole cell lysate
      All lanes: FANCF antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 43 kDa
      Observed band size: 43 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FANCF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FANCF
  • 別名:
    A730016A17 antibody; FACF antibody; FAF antibody; FANCF antibody; FANCF_HUMAN antibody; Fanconi anemia complementation group F antibody; Fanconi anemia group F protein antibody; MGC126856 antibody; Protein FACF antibody; RGD1561456 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fanconi anemia group F protein (295-341AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,FANCF Antibody (CSB-PA873614LA01HU),的標記方式是Non-conjugated。對于FANCF Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA873614LB01HU FANCF Antibody, HRP conjugated ELISA
    FITC CSB-PA873614LC01HU FANCF Antibody, FITC conjugated
    Biotin CSB-PA873614LD01HU FANCF Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:200-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
  • 基因功能參考文獻:
    1. LOH in FA genes appears to be a common feature of head and neck squamous cell carcinomas development seen here in 57% of patients and other mutation types may increase this mutation frequency. We suggest larger patient cohorts would be needed to test the observed association of LOH in FANCF and patient survival comprehensively PMID: 28440438
    2. we report three patients who illustrate the clinical variability within the FA-F group. This analysis suggests a more severe phenotype for those with the common c.484_485delCT mutation. PMID: 27714961
    3. CpG island methylation of FANCF gene promoter region is strongly associated with the susceptibility and clinicopathologic features of epithelial ovarian cancer. PMID: 26507869
    4. careful examination of three electively aborted fetuses in one family and one affected girl in the other indicated an association of the FANCF loss-of-function mutation with a severe phenotype characterized by multiple malformations PMID: 26033879
    5. Data suggest that the Fanconi anemia group F protein/BRCA1/2 proteins pathway may be a new target to reverse adriamycin (ADR) resistance in leukemia treatment. PMID: 24996439
    6. Silencing of FANCF enhanced the antiproliferative effect of ADM in OVCAR3 cells. PMID: 23440494
    7. FANCF methylation is a rare event in Japanese primary invasive breast cancer. PMID: 19813073
    8. Data identify the gene encoding Fanconi F (FANCF) as an ICSBP target gene. PMID: 19801548
    9. inactivation of the FANC-BRCA pathway is relatively common in solid tumors and may be related to tobacco and alcohol exposure and survival PMID: 14647419
    10. Inactivation of genes in the FA-BRCA pathway by epigenetic alterations have been found in a high proportion of cervix cancer patients, suggesting a major role for this pathway in the development of cervical cancer. PMID: 15126331
    11. FANCF acts as a flexible adaptor protein that plays a key role in the proper assembly of the FA core complex. PMID: 15262960
    12. results showed that FANCF methylation regulates the expression of FANCF at both mRNA and protein levels; methylation-induced inactivation of FANCF plays an important role in the occurrence of ovarian cancers via disrupting the FA-BRCA pathway PMID: 16418574
    13. human FANCF protein has specific structural components that function in the assembly of a DNA damage signaling complex PMID: 17082180
    14. FANCF methylation was rare in breast tumors PMID: 17932744
    15. This study does not support methylation-dependent silencing of FANCF as a mechanism of sensitisation to platinum-based chemotherapy in ovarian cancer. PMID: 18414472

    顯示更多

    收起更多

  • 相關疾病:
    Fanconi anemia complementation group F (FANCF)
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 3587

    OMIM: 603467

    KEGG: hsa:2188

    STRING: 9606.ENSP00000330875

    UniGene: Hs.632151



主站蜘蛛池模板: 韩国和日本免费不卡在线v| 亚洲 自拍 另类小说综合图区| 国产aⅴ视频免费观看| 日本熟妇hdsex视频| 丰满少妇高潮惨叫久久久| 天美麻花果冻视频大全英文版| 九色porny丨国产首页注册| 韩国无码av片在线观看| 国产亚洲精品自在久久vr| 好吊色欧美一区二区三区四区| 999国产精品999久久久久久| 日韩一卡二卡三卡四卡免费观在线 | 色天天天综合色天天| 无码少妇高潮浪潮av久久| 国产精品一区二区高清在线| 丁香花在线影院观看在线播放 | 欧美性猛交xxx嘿人猛交| 国产性生大片免费观看性| 激情综合婷婷色五月蜜桃| 亚洲国精产品一二二线| 男人的天堂av社区在线| 伊人婷婷六月狠狠狠去| 高级会所人妻互换94部分| 亚洲精品无码av黄瓜影视| 国色天香成人一区二区| 亚洲人成网站色7799| 99久久精品国产一区二区三区| 久久精品aⅴ无码中文字字幕不卡 男女啪啪无遮挡免费网站 | 国产成+人+综合+亚洲欧美丁香花| 精品一区二区三区影院在线午夜| 国产成人无码精品亚洲| 中文字幕在线免费看线人| 女乱高潮久久久久久爽爽| 中文字幕人妻第一区| 国产精品视频永久免费播放| 亚洲αⅴ无码乱码在线观看性色| 亚洲性线免费观看视频成熟 | 精品国产乱码久久久久久夜深人妻| 精品无人区麻豆乱码1区2区| 午夜人妻久久久久久久久| 国产-第1页-浮力影院|