在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FANCF Antibody

  • 中文名稱:
    FANCF兔多克隆抗體
  • 貨號:
    CSB-PA873614LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: HEK293 whole cell lysate, K562 whole cell lysate
      All lanes: FANCF antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 43 kDa
      Observed band size: 43 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FANCF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FANCF
  • 別名:
    A730016A17 antibody; FACF antibody; FAF antibody; FANCF antibody; FANCF_HUMAN antibody; Fanconi anemia complementation group F antibody; Fanconi anemia group F protein antibody; MGC126856 antibody; Protein FACF antibody; RGD1561456 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fanconi anemia group F protein (295-341AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,FANCF Antibody (CSB-PA873614LA01HU),的標記方式是Non-conjugated。對于FANCF Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA873614LB01HU FANCF Antibody, HRP conjugated ELISA
    FITC CSB-PA873614LC01HU FANCF Antibody, FITC conjugated
    Biotin CSB-PA873614LD01HU FANCF Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:200-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
  • 基因功能參考文獻:
    1. LOH in FA genes appears to be a common feature of head and neck squamous cell carcinomas development seen here in 57% of patients and other mutation types may increase this mutation frequency. We suggest larger patient cohorts would be needed to test the observed association of LOH in FANCF and patient survival comprehensively PMID: 28440438
    2. we report three patients who illustrate the clinical variability within the FA-F group. This analysis suggests a more severe phenotype for those with the common c.484_485delCT mutation. PMID: 27714961
    3. CpG island methylation of FANCF gene promoter region is strongly associated with the susceptibility and clinicopathologic features of epithelial ovarian cancer. PMID: 26507869
    4. careful examination of three electively aborted fetuses in one family and one affected girl in the other indicated an association of the FANCF loss-of-function mutation with a severe phenotype characterized by multiple malformations PMID: 26033879
    5. Data suggest that the Fanconi anemia group F protein/BRCA1/2 proteins pathway may be a new target to reverse adriamycin (ADR) resistance in leukemia treatment. PMID: 24996439
    6. Silencing of FANCF enhanced the antiproliferative effect of ADM in OVCAR3 cells. PMID: 23440494
    7. FANCF methylation is a rare event in Japanese primary invasive breast cancer. PMID: 19813073
    8. Data identify the gene encoding Fanconi F (FANCF) as an ICSBP target gene. PMID: 19801548
    9. inactivation of the FANC-BRCA pathway is relatively common in solid tumors and may be related to tobacco and alcohol exposure and survival PMID: 14647419
    10. Inactivation of genes in the FA-BRCA pathway by epigenetic alterations have been found in a high proportion of cervix cancer patients, suggesting a major role for this pathway in the development of cervical cancer. PMID: 15126331
    11. FANCF acts as a flexible adaptor protein that plays a key role in the proper assembly of the FA core complex. PMID: 15262960
    12. results showed that FANCF methylation regulates the expression of FANCF at both mRNA and protein levels; methylation-induced inactivation of FANCF plays an important role in the occurrence of ovarian cancers via disrupting the FA-BRCA pathway PMID: 16418574
    13. human FANCF protein has specific structural components that function in the assembly of a DNA damage signaling complex PMID: 17082180
    14. FANCF methylation was rare in breast tumors PMID: 17932744
    15. This study does not support methylation-dependent silencing of FANCF as a mechanism of sensitisation to platinum-based chemotherapy in ovarian cancer. PMID: 18414472

    顯示更多

    收起更多

  • 相關疾病:
    Fanconi anemia complementation group F (FANCF)
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 3587

    OMIM: 603467

    KEGG: hsa:2188

    STRING: 9606.ENSP00000330875

    UniGene: Hs.632151



主站蜘蛛池模板: 精品国产乱码久久久久久婷婷| 国内精品无码一区二区三区| 国产精品自在拍首页视频| 国产一区二区三区免费观看在线| 日本sm/羞辱/调教/捆绑视频| 四虎永久在线高清国产精品| 欧洲免费无线码在线一区| 美女mm131午夜福利在线| 蜜臀avwww国产天堂| www亚洲精品少妇裸乳一区二区| 人妻换人妻仑乱| 中文字幕无码精品三级在线电影| 日韩视频 中文字幕 视频一区| 日本免费大黄在线观看| 亚洲精品美女久久久久99 | 麻豆日产精品卡2卡3卡4卡5卡| 亚洲乱码伦小说区| 欧美人和黑人牲交网站上线| 亚洲国产成人精品无码区99| 亚洲va综合va国产产va中文| 久久人人爽人人爽爽久久小说| 国产精品午夜小视频观看| 中年熟妇的大黑p| 国产熟妇疯狂4p交在线播放| 精品国际久久久久999波多野| 内射少妇一区27p| 国产在线拍偷自揄拍无码| 国产情侣疯狂作爱系列| 无码毛片一区二区本码视频| 国产伦精品一区二区三区免费| 国产一区二区三区 韩国女主播| 国语对白嫖老妇胖老太| 国产全肉乱妇杂乱视频| 久久无码人妻丰满熟妇区毛片| 国产国产久热这里只有精品| 精品熟女少妇av久久免费软件 | 欧美老妇牲交videos| 亚洲精品久久66国产高清| 国产精品无码午夜福利| 亚洲熟妇av乱码在线观看| 亚洲另类欧美综合在线|