在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FANCF Antibody, Biotin conjugated

  • 中文名稱(chēng):
    FANCF兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA873614LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) FANCF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FANCF
  • 別名:
    A730016A17 antibody; FACF antibody; FAF antibody; FANCF antibody; FANCF_HUMAN antibody; Fanconi anemia complementation group F antibody; Fanconi anemia group F protein antibody; MGC126856 antibody; Protein FACF antibody; RGD1561456 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Fanconi anemia group F protein (295-341AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
  • 基因功能參考文獻(xiàn):
    1. LOH in FA genes appears to be a common feature of head and neck squamous cell carcinomas development seen here in 57% of patients and other mutation types may increase this mutation frequency. We suggest larger patient cohorts would be needed to test the observed association of LOH in FANCF and patient survival comprehensively PMID: 28440438
    2. we report three patients who illustrate the clinical variability within the FA-F group. This analysis suggests a more severe phenotype for those with the common c.484_485delCT mutation. PMID: 27714961
    3. CpG island methylation of FANCF gene promoter region is strongly associated with the susceptibility and clinicopathologic features of epithelial ovarian cancer. PMID: 26507869
    4. careful examination of three electively aborted fetuses in one family and one affected girl in the other indicated an association of the FANCF loss-of-function mutation with a severe phenotype characterized by multiple malformations PMID: 26033879
    5. Data suggest that the Fanconi anemia group F protein/BRCA1/2 proteins pathway may be a new target to reverse adriamycin (ADR) resistance in leukemia treatment. PMID: 24996439
    6. Silencing of FANCF enhanced the antiproliferative effect of ADM in OVCAR3 cells. PMID: 23440494
    7. FANCF methylation is a rare event in Japanese primary invasive breast cancer. PMID: 19813073
    8. Data identify the gene encoding Fanconi F (FANCF) as an ICSBP target gene. PMID: 19801548
    9. inactivation of the FANC-BRCA pathway is relatively common in solid tumors and may be related to tobacco and alcohol exposure and survival PMID: 14647419
    10. Inactivation of genes in the FA-BRCA pathway by epigenetic alterations have been found in a high proportion of cervix cancer patients, suggesting a major role for this pathway in the development of cervical cancer. PMID: 15126331
    11. FANCF acts as a flexible adaptor protein that plays a key role in the proper assembly of the FA core complex. PMID: 15262960
    12. results showed that FANCF methylation regulates the expression of FANCF at both mRNA and protein levels; methylation-induced inactivation of FANCF plays an important role in the occurrence of ovarian cancers via disrupting the FA-BRCA pathway PMID: 16418574
    13. human FANCF protein has specific structural components that function in the assembly of a DNA damage signaling complex PMID: 17082180
    14. FANCF methylation was rare in breast tumors PMID: 17932744
    15. This study does not support methylation-dependent silencing of FANCF as a mechanism of sensitisation to platinum-based chemotherapy in ovarian cancer. PMID: 18414472

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Fanconi anemia complementation group F (FANCF)
  • 亞細(xì)胞定位:
    Nucleus.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 3587

    OMIM: 603467

    KEGG: hsa:2188

    STRING: 9606.ENSP00000330875

    UniGene: Hs.632151



主站蜘蛛池模板: 精品无人乱码高清在线观看| 亚洲精品久久久一二三区 | 精品久久久久久中文字幕大豆网| 少妇高潮一区二区三区99| 日韩精品久久久久久久电影蜜臀| 青青草国产线观看| av性色av久久无码ai换脸| 手机福利视频| 好大好湿好硬顶到了好爽视频| 无码中文字幕av免费放| 亚洲一卡2卡3卡4卡5卡乱码观看| 久久国产精品波多野结衣av| 法国啄木乌av片在线播放| 亚洲国产精品一区二区手机| 99久久er热在这里只有精品99| 国产内射爽爽大片视频社区在线| 人人爽人人爽人人片a| 让少妇高潮无乱码高清在线观看| 中文无码精品一区二区三区| 亚洲精品国产品国语在线| 国产xxxx做受视频| 玩50岁四川熟女大白屁股直播| 国产成人精品久久| 日本老熟妇乱| 无套内射chinesehd熟女| 欧美变态口味重另类在线视频| 日韩va中文字幕无码电影| 污18禁污色黄网站免费| 亚洲男人的天堂www| 婷婷色婷婷开心五月四房播播| 久久aⅴ无码av高潮av喷吹| 影音先锋无码a∨男人资源站 | 99久久亚洲精品无码毛片 | 色欲αv一区二区三区天美传媒| 偷拍农村老熟妇xxxxx7视频| 国产精品视频| 久爱无码精品免费视频在线观看| 一区二区在线 | 国| 日本爽爽爽爽爽爽在线观看免| 大肉大捧一进一出好爽app| 免费人成网站在线观看视频|