在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FANCF Antibody, FITC conjugated

  • 中文名稱:
    FANCF兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA873614LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FANCF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FANCF
  • 別名:
    A730016A17 antibody; FACF antibody; FAF antibody; FANCF antibody; FANCF_HUMAN antibody; Fanconi anemia complementation group F antibody; Fanconi anemia group F protein antibody; MGC126856 antibody; Protein FACF antibody; RGD1561456 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fanconi anemia group F protein (295-341AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
  • 基因功能參考文獻:
    1. LOH in FA genes appears to be a common feature of head and neck squamous cell carcinomas development seen here in 57% of patients and other mutation types may increase this mutation frequency. We suggest larger patient cohorts would be needed to test the observed association of LOH in FANCF and patient survival comprehensively PMID: 28440438
    2. we report three patients who illustrate the clinical variability within the FA-F group. This analysis suggests a more severe phenotype for those with the common c.484_485delCT mutation. PMID: 27714961
    3. CpG island methylation of FANCF gene promoter region is strongly associated with the susceptibility and clinicopathologic features of epithelial ovarian cancer. PMID: 26507869
    4. careful examination of three electively aborted fetuses in one family and one affected girl in the other indicated an association of the FANCF loss-of-function mutation with a severe phenotype characterized by multiple malformations PMID: 26033879
    5. Data suggest that the Fanconi anemia group F protein/BRCA1/2 proteins pathway may be a new target to reverse adriamycin (ADR) resistance in leukemia treatment. PMID: 24996439
    6. Silencing of FANCF enhanced the antiproliferative effect of ADM in OVCAR3 cells. PMID: 23440494
    7. FANCF methylation is a rare event in Japanese primary invasive breast cancer. PMID: 19813073
    8. Data identify the gene encoding Fanconi F (FANCF) as an ICSBP target gene. PMID: 19801548
    9. inactivation of the FANC-BRCA pathway is relatively common in solid tumors and may be related to tobacco and alcohol exposure and survival PMID: 14647419
    10. Inactivation of genes in the FA-BRCA pathway by epigenetic alterations have been found in a high proportion of cervix cancer patients, suggesting a major role for this pathway in the development of cervical cancer. PMID: 15126331
    11. FANCF acts as a flexible adaptor protein that plays a key role in the proper assembly of the FA core complex. PMID: 15262960
    12. results showed that FANCF methylation regulates the expression of FANCF at both mRNA and protein levels; methylation-induced inactivation of FANCF plays an important role in the occurrence of ovarian cancers via disrupting the FA-BRCA pathway PMID: 16418574
    13. human FANCF protein has specific structural components that function in the assembly of a DNA damage signaling complex PMID: 17082180
    14. FANCF methylation was rare in breast tumors PMID: 17932744
    15. This study does not support methylation-dependent silencing of FANCF as a mechanism of sensitisation to platinum-based chemotherapy in ovarian cancer. PMID: 18414472

    顯示更多

    收起更多

  • 相關疾病:
    Fanconi anemia complementation group F (FANCF)
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 3587

    OMIM: 603467

    KEGG: hsa:2188

    STRING: 9606.ENSP00000330875

    UniGene: Hs.632151



主站蜘蛛池模板: 午夜伦yy44880影院| 国产免费久久精品99久久| 亚洲va欧美va天堂v国产综合| 在线观看国产丝袜控网站| 2019最新中文字幕在线观看| 欧美日韩精品一区二区在线观看| 午夜福利无码不卡在线观看| 国产精品婷婷久久爽一下| 99久久精品免费看国产一区二区三区| 国产成人+亚洲欧洲+综合| 国内久久婷婷五月综合色| 成人亚洲欧美日韩在线观看| 久久99精品久久久久久hb亚瑟| 琪琪午夜伦埋影院77| 日韩欧美人妻一区二区三区| 亚洲欧美日韩综合在线一| 亚洲国产成人无码av在线播放| 免费人成在线观看网站品爱网| 中文无码日韩欧免费视频| 东京热加勒比无码少妇| 曰本女人与公拘交酡| 国产国拍精品av在线观看| 狠狠色老熟妇老熟女| 亚洲国产美女精品久久久久| 2024av天堂手机在线观看| 丰满人妻一区二区三区无码av | 2021年国产精品专区丝袜| 久久大蕉香蕉免费| 朝鲜女子内射杂交bbw| 久久中文字幕人妻熟av女| 美女裸体十八禁免费网站| 精品少妇人妻av久久久 | 日日摸日日碰夜夜爽亚洲| 窝窝午夜理论片影院| 风流老熟女一区二区三区| 四虎影视无码永久免费| 久久久精品94久久精品| 国产亚洲精品久久久久久青梅| 欧美性欧美巨大黑白大战| 国产午夜亚洲精品理论片不卡| 欧美最新精品videossexohd|