在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CHSY1 Antibody

CHSY1 Antibody

  • 中文名稱：
    CHSY1兔多克隆抗體
  • 貨號：
    CSB-PA005416LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA005416LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA005416LA01HU diluted at 1:300 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CHSY1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CHSY1
  • 別名：
    Carbohydrate synthase 1 antibody; Chondroitin glucuronyltransferase 1 antibody; Chondroitin glucuronyltransferase II antibody; Chondroitin sulfate synthase 1 antibody; Chondroitin synthase 1 antibody; CHSS1_HUMAN antibody; CHSY antibody; ChSy-1 antibody; Chsy1 antibody; CSS1 antibody; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1 antibody; N acetylgalactosaminyltransferase II antibody; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 antibody; N-acetylgalactosaminyltransferase 1 antibody; TPBS antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Chondroitin sulfate synthase 1 protein (32-148AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，CHSY1 Antibody (CSB-PA005416LA01HU)，的標記方式是Non-conjugated。對于CHSY1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA005416LB01HU CHSY1 Antibody, HRP conjugated ELISA
    FITC CSB-PA005416LC01HU CHSY1 Antibody, FITC conjugated
    Biotin CSB-PA005416LD01HU CHSY1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
  • 基因功能參考文獻：
    1. CHSY1 overexpression in HCC contributes to the malignant behavior of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. PMID: 28652022
    2. CHSY1 expression is closely associated with malignant potential of soft tissue sarcomas with myxoid substance. PMID: 26997434
    3. A novel missense mutation (c.1897 G > A) in the CHSY1 gene in two Temtamy preaxial brachydactyly syndrome patients from a consanguineous Pakistani family. PMID: 24269551
    4. elongation of chondroitin sulfate chains may be tightly regulated by the cooperative expression of chondroitin synthase-1 and chondroitin N-acetylgalactosaminyltransferase-1 in peripheral neurons and peripheral neuropathies PMID: 23811343
    5. The present study focused on the expression of chondroitin-synthesizing enzymes in colorectal cancer. PMID: 21468578
    6. conclude that CHSY1 is a secreted FRINGE enzyme required for adjustment of NOTCH signaling throughout human and fish embryogenesis and particularly during limb patterning PMID: 21129727
    7. unrestricted Bmp2b signaling or loss of Dan activity leads to reduced chsy1 expression and, during epithelial morphogenesis, defects similar to those that occur upon Chsy1 inactivation PMID: 21129728
    8. chondroitin polymerizing activity requires concomitant expression of a ChPF with ChSy; coexpression of the ChPF and ChSy yielded markedly augmented glycosyltransferase activities, whereas simple mixing of the two separately expressed proteins did not. PMID: 12716890

    顯示更多

    收起更多

  • 相關疾病：
    Temtamy preaxial brachydactyly syndrome (TPBS)
  • 亞細胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
  • 蛋白家族：
    Chondroitin N-acetylgalactosaminyltransferase family
  • 組織特異性：
    Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
  • 數據庫鏈接：

    HGNC: 17198

    OMIM: 605282

    KEGG: hsa:22856

    STRING: 9606.ENSP00000254190

    UniGene: Hs.110488



主站蜘蛛池模板： 四川骚妇无套内射舔了更爽| 午夜裸体性播放| 久久超碰色中文字幕超清| 亚洲国产成人精品无码区花野真一| 久久久婷婷五月亚洲97色| 精品国产亚洲一区二区三区在线观看| 国产精品久久午夜夜伦鲁鲁| 国产真人无码作爱视频免费| 亚洲中文字幕不卡无码| 图片区小说区另类春色| 国产热の有码热の无码视频| 另类老妇奶性生bbwbbw| 在线播放真实国产乱子伦| 国产片av片永久免费观看| 国产在线视频一区二区三区| 国产精品人妻| 欧美日韩不卡高清在线看| 亚洲综合激情五月丁香六月| 欧美寡妇xxxx黑人猛交| 欧美成人精品手机在线| 99re6热精品视频在线观看| 色综合a怡红院怡红院| 色妞www精品视频| 98国产精品综合一区二区三区| 无码熟熟妇丰满人妻啪啪| 天堂岛国av无码免费无禁网站| 亚洲精品无码不卡在线播放| 婷婷五月小说| 97久久久久人妻精品区一| 边啃奶头边躁狠狠躁玩爽在水里面| 亚洲性夜色噜噜噜在线观看不卡| 一本一道av无码中文字幕﹣百度| 国产精品sp调教打屁股| 在线播放十八禁视频无遮挡| 久久天天躁狠狠躁夜夜躁app| 野外做受三级视频| 野狼第一精品社区| 亚洲综合无码av一区二区三区| 色欲网天天无码av| 天堂√最新版中文在线地址| 国产成人精品久久久久精品日日|