在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CHSY1 Antibody, HRP conjugated

  • 中文名稱:
    CHSY1兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA005416LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) CHSY1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CHSY1
  • 別名:
    Carbohydrate synthase 1 antibody; Chondroitin glucuronyltransferase 1 antibody; Chondroitin glucuronyltransferase II antibody; Chondroitin sulfate synthase 1 antibody; Chondroitin synthase 1 antibody; CHSS1_HUMAN antibody; CHSY antibody; ChSy-1 antibody; Chsy1 antibody; CSS1 antibody; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1 antibody; N acetylgalactosaminyltransferase II antibody; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 antibody; N-acetylgalactosaminyltransferase 1 antibody; TPBS antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Chondroitin sulfate synthase 1 protein (32-148AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
  • 基因功能參考文獻:
    1. CHSY1 overexpression in HCC contributes to the malignant behavior of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. PMID: 28652022
    2. CHSY1 expression is closely associated with malignant potential of soft tissue sarcomas with myxoid substance. PMID: 26997434
    3. A novel missense mutation (c.1897 G > A) in the CHSY1 gene in two Temtamy preaxial brachydactyly syndrome patients from a consanguineous Pakistani family. PMID: 24269551
    4. elongation of chondroitin sulfate chains may be tightly regulated by the cooperative expression of chondroitin synthase-1 and chondroitin N-acetylgalactosaminyltransferase-1 in peripheral neurons and peripheral neuropathies PMID: 23811343
    5. The present study focused on the expression of chondroitin-synthesizing enzymes in colorectal cancer. PMID: 21468578
    6. conclude that CHSY1 is a secreted FRINGE enzyme required for adjustment of NOTCH signaling throughout human and fish embryogenesis and particularly during limb patterning PMID: 21129727
    7. unrestricted Bmp2b signaling or loss of Dan activity leads to reduced chsy1 expression and, during epithelial morphogenesis, defects similar to those that occur upon Chsy1 inactivation PMID: 21129728
    8. chondroitin polymerizing activity requires concomitant expression of a ChPF with ChSy; coexpression of the ChPF and ChSy yielded markedly augmented glycosyltransferase activities, whereas simple mixing of the two separately expressed proteins did not. PMID: 12716890

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Temtamy preaxial brachydactyly syndrome (TPBS)
  • 亞細胞定位:
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
  • 蛋白家族:
    Chondroitin N-acetylgalactosaminyltransferase family
  • 組織特異性:
    Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 17198

    OMIM: 605282

    KEGG: hsa:22856

    STRING: 9606.ENSP00000254190

    UniGene: Hs.110488



主站蜘蛛池模板: 欧美亚洲国产手机在线有码| 在线观看老湿视频福利| 亚洲熟女乱综合一区二区| 四虎影视久久久免费观看| 在线播放十八禁视频无遮挡| 美女扒开奶罩露出奶头视频网站| 丰满少妇夜夜爽爽高潮水| 婷婷综合缴情亚洲狠狠小说 | 特级aaaaaaaaa毛片免费视频| 色一情一乱一伦一区二区三区日本 | 色婷婷综合久久久久中文| 欧美老熟妇乱大交xxxxx | 亚洲综合色在线观看一区| mm1313亚洲国产精品无码试看| 香蕉影院在线观看| s级爆乳玩具酱国产vip皮裤| 国产午夜无码片在线观看影视| 亚洲国产精品无码观看久久| 精品乱码一区二区三四区视频| 色综合av男人的天堂伊人| 人妻少妇偷人无码视频| 精品精品国产高清a毛片| 久久99精品久久久久婷婷 | 人妻熟女一二三区夜夜爱| 精品系列无码一区二区三区| 国产午夜福利伦理300| 一本大道熟女人妻中文字幕在线 | 五十路熟妇亲子交尾| aaa欧美色吧激情视频| 国产精品一区在线观看你懂的| 日韩中文字幕免费视频| 久久伊人精品波多野结衣| 日本少妇人妻xxxxx18| 欧美日韩亚洲精品瑜伽裤| 色综合欧美在线视频区| 成人亚欧欧美激情在线观看| 野花社区www视频最新资源| 狠狠cao日日穞夜夜穞av| 亚洲小说图区综合在线| 精品一区二区三区影院在线午夜| 国产精品无码午夜福利|