在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CHSY1 Antibody, Biotin conjugated

  • 中文名稱:
    CHSY1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA005416LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CHSY1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CHSY1
  • 別名:
    Carbohydrate synthase 1 antibody; Chondroitin glucuronyltransferase 1 antibody; Chondroitin glucuronyltransferase II antibody; Chondroitin sulfate synthase 1 antibody; Chondroitin synthase 1 antibody; CHSS1_HUMAN antibody; CHSY antibody; ChSy-1 antibody; Chsy1 antibody; CSS1 antibody; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1 antibody; N acetylgalactosaminyltransferase II antibody; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 antibody; N-acetylgalactosaminyltransferase 1 antibody; TPBS antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Chondroitin sulfate synthase 1 protein (32-148AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
  • 基因功能參考文獻:
    1. CHSY1 overexpression in HCC contributes to the malignant behavior of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. PMID: 28652022
    2. CHSY1 expression is closely associated with malignant potential of soft tissue sarcomas with myxoid substance. PMID: 26997434
    3. A novel missense mutation (c.1897 G > A) in the CHSY1 gene in two Temtamy preaxial brachydactyly syndrome patients from a consanguineous Pakistani family. PMID: 24269551
    4. elongation of chondroitin sulfate chains may be tightly regulated by the cooperative expression of chondroitin synthase-1 and chondroitin N-acetylgalactosaminyltransferase-1 in peripheral neurons and peripheral neuropathies PMID: 23811343
    5. The present study focused on the expression of chondroitin-synthesizing enzymes in colorectal cancer. PMID: 21468578
    6. conclude that CHSY1 is a secreted FRINGE enzyme required for adjustment of NOTCH signaling throughout human and fish embryogenesis and particularly during limb patterning PMID: 21129727
    7. unrestricted Bmp2b signaling or loss of Dan activity leads to reduced chsy1 expression and, during epithelial morphogenesis, defects similar to those that occur upon Chsy1 inactivation PMID: 21129728
    8. chondroitin polymerizing activity requires concomitant expression of a ChPF with ChSy; coexpression of the ChPF and ChSy yielded markedly augmented glycosyltransferase activities, whereas simple mixing of the two separately expressed proteins did not. PMID: 12716890

    顯示更多

    收起更多

  • 相關疾病:
    Temtamy preaxial brachydactyly syndrome (TPBS)
  • 亞細胞定位:
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
  • 蛋白家族:
    Chondroitin N-acetylgalactosaminyltransferase family
  • 組織特異性:
    Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 17198

    OMIM: 605282

    KEGG: hsa:22856

    STRING: 9606.ENSP00000254190

    UniGene: Hs.110488



主站蜘蛛池模板: 菠萝蜜视频在线观看入口| 日韩美女自卫慰黄网站| 卡1卡2卡3精品接入口| 国产精品高潮呻吟av久久男男| 亚洲精品亚洲人成在线下载| 欧美俄罗斯乱妇| 吃奶呻吟打开双腿做受在线视频| 亚洲精品一品区二品区三区| 欧美人与禽zozzo性伦交| 久久一卡二卡三卡四卡| 无码视频在线观看| 成人毛片无码一区二区三区 | www国产亚洲精品久久网站| 综合无码精品人妻一区二区三区| av无码国产在线看免费网站| 日日摸日日碰夜夜爽av| 亚洲第一无码精品立川理惠| 人人妻在人人| 欧美激欧美啪啪片免费看| 动漫精品无码h在线观看| 老子影院午夜伦手机不四虎卡| 久久综合给合综合久久| 呦男呦女视频精品八区| 动漫av纯肉无码免费播放| 717影院理论午夜伦八戒| 亚洲日韩国产精品第一页一区| 精品无码中文视频在线观看| 在线视频精品免费观看10| 国产偷久久久精品专区| 亚洲色国产欧美日韩| 波多野结衣av无码久久一区| 欧美中日韩免费观看网站| 亚洲成av人的天堂在线观看| 国产成人精品a视频| 欧美老妇bbbwwbbbww| 无码一区二区三区av免费蜜桃| 成人做爰视频www| 99久久综合狠狠综合久久止 | 亚洲成在人线av| 一区三区不卡高清影视| 日韩放荡少妇无码视频|