在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CHSY1 Antibody

  • 中文名稱:
    CHSY1兔多克隆抗體
  • 貨號:
    CSB-PA005416GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CHSY1
  • 別名:
    Carbohydrate synthase 1 antibody; Chondroitin glucuronyltransferase 1 antibody; Chondroitin glucuronyltransferase II antibody; Chondroitin sulfate synthase 1 antibody; Chondroitin synthase 1 antibody; CHSS1_HUMAN antibody; CHSY antibody; ChSy-1 antibody; Chsy1 antibody; CSS1 antibody; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1 antibody; N acetylgalactosaminyltransferase II antibody; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 antibody; N-acetylgalactosaminyltransferase 1 antibody; TPBS antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat,Zebrafish
  • 免疫原:
    Human CHSY1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
  • 基因功能參考文獻:
    1. CHSY1 overexpression in HCC contributes to the malignant behavior of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. PMID: 28652022
    2. CHSY1 expression is closely associated with malignant potential of soft tissue sarcomas with myxoid substance. PMID: 26997434
    3. A novel missense mutation (c.1897 G > A) in the CHSY1 gene in two Temtamy preaxial brachydactyly syndrome patients from a consanguineous Pakistani family. PMID: 24269551
    4. elongation of chondroitin sulfate chains may be tightly regulated by the cooperative expression of chondroitin synthase-1 and chondroitin N-acetylgalactosaminyltransferase-1 in peripheral neurons and peripheral neuropathies PMID: 23811343
    5. The present study focused on the expression of chondroitin-synthesizing enzymes in colorectal cancer. PMID: 21468578
    6. conclude that CHSY1 is a secreted FRINGE enzyme required for adjustment of NOTCH signaling throughout human and fish embryogenesis and particularly during limb patterning PMID: 21129727
    7. unrestricted Bmp2b signaling or loss of Dan activity leads to reduced chsy1 expression and, during epithelial morphogenesis, defects similar to those that occur upon Chsy1 inactivation PMID: 21129728
    8. chondroitin polymerizing activity requires concomitant expression of a ChPF with ChSy; coexpression of the ChPF and ChSy yielded markedly augmented glycosyltransferase activities, whereas simple mixing of the two separately expressed proteins did not. PMID: 12716890

    顯示更多

    收起更多

  • 相關疾病:
    Temtamy preaxial brachydactyly syndrome (TPBS)
  • 亞細胞定位:
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
  • 蛋白家族:
    Chondroitin N-acetylgalactosaminyltransferase family
  • 組織特異性:
    Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 17198

    OMIM: 605282

    KEGG: hsa:22856

    STRING: 9606.ENSP00000254190

    UniGene: Hs.110488



主站蜘蛛池模板: 亚洲熟妇av一区二区三区| 澳门永久av免费网站| 国产内射爽爽大片视频社区在线| 四虎国产成人永久精品免费| 国产麻豆乱子伦午夜视频观看| 亚洲精品无码av专区最新| 精品视频国产狼友视频| 伊人中文字幕无码专区| 欧洲精品免费一区二区三区| 国产精品亚洲а∨天堂2021| 亚洲欧洲美洲无码精品va| 女人被躁到高潮免费视频| 久久久久久一区国产精品| 福利姬国产精品一区在线| 午夜dj在线观看免费视频| 99久久精品免费看国产一区二区三区| 伊在人天堂亚洲香蕉精品区| 久久精品私人影院免费看| 亚洲色素色无码专区| 男人的天堂在线视频| 国产精品久久久久久久9999| 日产日韩亚洲欧美综合下载| 精品伊人久久久大香线蕉下载 | 亚洲午夜精品久久久久久人妖| 唐人社导航福利精品| 欧美牲交a欧美牲交aⅴ图片| 色天使亚洲综合一区二区| 欧美成人aa大片| 亚欧免费无码aⅴ在线观看| 亚洲乱亚洲乱妇无码| 中文天堂在线资源www| 吃奶揉捏奶头高潮视频| 无码人妻精品一区二区蜜桃色欲| 女人被狂躁c到高潮视频| 日韩精品无码人妻一区二区三区| 国产综合18久久久久久| 人妻熟女一区| 日韩精品久久久肉伦网站| 亚洲精品成人网线在线播放va| 久久精晶国产99久久6| 成人国产精品一区二区网站公司|