在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CCL13 Antibody

CCL13 Antibody

  • 中文名稱：
    CCL13兔多克隆抗體
  • 貨號：
    CSB-PA908097
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA908097(CCL13 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA908097(CCL13 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    C-C motif chemokine 13 antibody; CCL13 antibody; CCL13_HUMAN antibody; Chemokine (C C motif) ligand 13 antibody; CK beta 10 antibody; CK-beta-10 antibody; CKb10 antibody; MCP-4 antibody; MGC17134 antibody; Monocyte chemoattractant protein 4 antibody; Monocyte chemotactic protein 4 antibody; NCC 1 antibody; NCC-1 antibody; NCC1 antibody; New CC chemokine 1 antibody; SCYA13 antibody; SCYL1 antibody; short chain antibody; Small inducible cytokine A13 precursor antibody; Small inducible cytokine subfamily A (Cys Cys) member 13 antibody; Small-inducible cytokine A13 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human CCL13
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:30-1:150
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
  • 基因功能參考文獻：
    1. CCL13 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. CCL13 levels in serum and synovial fluid may serve as a biomarker for the progression of osteoarthritis. PMID: 25654294
    3. CCL13 is an antimicrobial protein with bacteriocidal activity against E. coli. PMID: 12949249
    4. Data suggest that CCL13 binds to several chemokine receptors (CCR1, CCR2, and CCR3), allowing CCL13 to elicit different effects on target cells of immune system. CCL13 is involved in pathology of chronic inflammatory/autoimmune diseases. [REVIEW] PMID: 23846739
    5. MCP-4 and hsCRP may be the markers linking chronic inflammation in obesity and periodontal disease. PMID: 23375121
    6. E(2) has adverse effects on the pathogenesis of RA as a result of unregulated cell death, increased TNF-alpha-induced MMP-3 production, and CCL13 overproduction, subsequently resulting in the disease progression of RA. PMID: 22393877
    7. Findings suggest that the pro-atherogenic effects of CCR2 may not be restricted to interaction with MCP-1, but could also involve activation by MCP-4, being an inflammatory link between platelet and monocyte activation. PMID: 20139115
    8. Data suggest that the monocyte chemoattractant protein-4 core promoter YY-1 binding motif is functional, and modulates the transcriptional regulation of the MCP-4 gene. PMID: 12805085
    9. The study was undertaken to understand the relationship between the functional proteomics of receptor-Ck and developmental stages of human atherosclerotic aortic wall. PMID: 14560935
    10. MCP-4 may be a critical molecule that links obesity and chronic inflammation. PMID: 16855189
    11. The Th2 cytokine IL-4 preferentially stimulated MCP-4 expression. PMID: 17541284
    12. interferon-gamma with IL-1beta/TNF-alpha activates the production of CCL13 from chondrocytes in RA joints; secreted CCL13 enhances fibroblast-like synoviocyte proliferation by activating the extracellular signal-regulated MAP kinases cascade PMID: 17824960
    13. TLR2, 3, 4 and 5 ligands, but not TLR7/8 or 9 ligands, synergized with IL-4 to induce the production of MCP-4 in nasal polyp fibroblasts. PMID: 17851891
    14. CCL13 and HSPC159 mRNA expressions in PBMC are up-regulated specifically in MCNS patients during the nephrosis phase. PMID: 18219197
    15. Oncostatin M can strongly up-regulate the expression of CCL13, a chemokine recently identified in the synovial fluid of patients with rheumatoid arthritis. PMID: 19565514

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine beta (chemokine CC) family
  • 組織特異性：
    Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
  • 數據庫鏈接：

    HGNC: 10611

    OMIM: 601391

    KEGG: hsa:6357

    STRING: 9606.ENSP00000225844

    UniGene: Hs.414629



主站蜘蛛池模板： 色丁香婷婷综合久久| 久久精品av一区二区免费| 国产日产欧产精品品不卡| 伊伊人成亚洲综合人网7777| 人妻妺妺窝人体色www聚色窝| 玩弄漂亮少妇高潮白浆 | 国产欧美综合一区二区三区| 一本久久综合亚洲鲁鲁五月天| 337p亚洲日本中国大胆69| 无码人妻在线一区二区三区免费| 久久99精品九九九久久婷婷| 中文字幕在线免费看线人| 国产天堂久久天堂av色综合| 精产国品一二三产品麻豆| 狠狠噜天天噜日日噜视频麻豆| 一本色道久久综合无码人妻| 日韩av无码久久一区二区| 日韩a片无码一区二区三区电影| 国产无遮挡18禁无码网站免费| 内射无码专区久久亚洲| s级爆乳玩具酱国产vip皮裤 | 免费观看啪啪黄的网站| 国产精品欧美久久久久无广告| 国产亚洲精品字幕在线观看 | 一区二区无码免费视频网站| 成人免费网站视频www| 欧美人与动另类xxxx| 成人无码www免费视频| 国产女人高潮嗷嗷嗷叫| 精品一区二区成人精品| 日本中文字幕在线| 狠狠五月深爱婷婷网| 非洲黑人性xxxx精品| 亚洲精品成人福利网站app| 亚洲国产精品嫩草影院| 久久精品中文无码资源站| 国内精品乱码卡一卡2卡| 狠狠综合久久综合88亚洲| 狠狠躁夜夜躁人人爽天天天天97 | 国产粉嫩小泬在线观看泬| 国产免费午夜a无码v视频|