在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CCL13 Antibody

CCL13 Antibody

  • 中文名稱：
    CCL13兔多克隆抗體
  • 貨號：
    CSB-PA218529
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 12%SDS-PAGE, Lysate: 50 μg, Lane: 293T cells, Primary antibody: CSB-PA218529(CCL13 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    C-C motif chemokine 13 antibody; CCL13 antibody; CCL13_HUMAN antibody; Chemokine (C C motif) ligand 13 antibody; CK beta 10 antibody; CK-beta-10 antibody; CKb10 antibody; MCP-4 antibody; MGC17134 antibody; Monocyte chemoattractant protein 4 antibody; Monocyte chemotactic protein 4 antibody; NCC 1 antibody; NCC-1 antibody; NCC1 antibody; New CC chemokine 1 antibody; SCYA13 antibody; SCYL1 antibody; short chain antibody; Small inducible cytokine A13 precursor antibody; Small inducible cytokine subfamily A (Cys Cys) member 13 antibody; Small-inducible cytokine A13 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human CCL13
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
  • 基因功能參考文獻：
    1. CCL13 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. CCL13 levels in serum and synovial fluid may serve as a biomarker for the progression of osteoarthritis. PMID: 25654294
    3. CCL13 is an antimicrobial protein with bacteriocidal activity against E. coli. PMID: 12949249
    4. Data suggest that CCL13 binds to several chemokine receptors (CCR1, CCR2, and CCR3), allowing CCL13 to elicit different effects on target cells of immune system. CCL13 is involved in pathology of chronic inflammatory/autoimmune diseases. [REVIEW] PMID: 23846739
    5. MCP-4 and hsCRP may be the markers linking chronic inflammation in obesity and periodontal disease. PMID: 23375121
    6. E(2) has adverse effects on the pathogenesis of RA as a result of unregulated cell death, increased TNF-alpha-induced MMP-3 production, and CCL13 overproduction, subsequently resulting in the disease progression of RA. PMID: 22393877
    7. Findings suggest that the pro-atherogenic effects of CCR2 may not be restricted to interaction with MCP-1, but could also involve activation by MCP-4, being an inflammatory link between platelet and monocyte activation. PMID: 20139115
    8. Data suggest that the monocyte chemoattractant protein-4 core promoter YY-1 binding motif is functional, and modulates the transcriptional regulation of the MCP-4 gene. PMID: 12805085
    9. The study was undertaken to understand the relationship between the functional proteomics of receptor-Ck and developmental stages of human atherosclerotic aortic wall. PMID: 14560935
    10. MCP-4 may be a critical molecule that links obesity and chronic inflammation. PMID: 16855189
    11. The Th2 cytokine IL-4 preferentially stimulated MCP-4 expression. PMID: 17541284
    12. interferon-gamma with IL-1beta/TNF-alpha activates the production of CCL13 from chondrocytes in RA joints; secreted CCL13 enhances fibroblast-like synoviocyte proliferation by activating the extracellular signal-regulated MAP kinases cascade PMID: 17824960
    13. TLR2, 3, 4 and 5 ligands, but not TLR7/8 or 9 ligands, synergized with IL-4 to induce the production of MCP-4 in nasal polyp fibroblasts. PMID: 17851891
    14. CCL13 and HSPC159 mRNA expressions in PBMC are up-regulated specifically in MCNS patients during the nephrosis phase. PMID: 18219197
    15. Oncostatin M can strongly up-regulate the expression of CCL13, a chemokine recently identified in the synovial fluid of patients with rheumatoid arthritis. PMID: 19565514

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine beta (chemokine CC) family
  • 組織特異性：
    Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
  • 數據庫鏈接：

    HGNC: 10611

    OMIM: 601391

    KEGG: hsa:6357

    STRING: 9606.ENSP00000225844

    UniGene: Hs.414629



主站蜘蛛池模板： 国产一区二区三区不卡在线看| 青青青青国产免费线在线观看| 亚洲成av人在线观看天堂无码| 日日日日做夜夜夜夜无码 | 午夜日本大胆裸艺术| xx性欧美肥妇精品久久久久久| 国产精品久久久久久久妇| 国内一区二区三区香蕉aⅴ| 人妻无码中文专区久久五月婷| 久久精品蜜芽亚洲国产av| 成人做爰免费视频免费看| 人妻护士在线波多野结衣| 国产 制服丝袜 动漫在线| 窝窝午夜理论片影院| 狠狠五月深爱婷婷网| 337p日本大胆欧久久| 国产成_人_综合_亚洲_国产| 欧洲国产伦久久久久久久| 俄罗斯大荫蒂女人毛茸茸 | 一本大道大臿蕉视频无码| 最新高清无码专区| 成人影片麻豆国产影片免费观看| 国产情侣激情在线视频| 亚洲精品久久午夜麻豆| 亚洲精品夜夜夜| 免费观看又污又黄在线观看| 日本国产成人国产在线播放| 小草社区视频在线观看| 成 年 人 黄 色 大 片大 全| 亚洲欧美日本国产专区一区| 欧美特黄特色三级视频在线观看| 一区二区三区国产精华液| 女人被狂躁的高潮免费视频 | 日韩av无码成人无码免费 | 久久精品中文字幕有码| 水蜜桃色314在线观看| 成人欧美一区二区三区黑人免费 | 无码人妻一区二区三区四区av| 中文字幕无码免费久久| 久久国产精品无码hdav| 五月婷婷久久草|