在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CCL13 Antibody

CCL13 Antibody

  • 中文名稱：
    CCL13兔多克隆抗體
  • 貨號：
    CSB-PA937680
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 12%SDS-PAGE, Lysate: 50 μg, Lane: 293T cells, Primary antibody: CSB-PA937680(CCL13 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    C-C motif chemokine 13 antibody; CCL13 antibody; CCL13_HUMAN antibody; Chemokine (C C motif) ligand 13 antibody; CK beta 10 antibody; CK-beta-10 antibody; CKb10 antibody; MCP-4 antibody; MGC17134 antibody; Monocyte chemoattractant protein 4 antibody; Monocyte chemotactic protein 4 antibody; NCC 1 antibody; NCC-1 antibody; NCC1 antibody; New CC chemokine 1 antibody; SCYA13 antibody; SCYL1 antibody; short chain antibody; Small inducible cytokine A13 precursor antibody; Small inducible cytokine subfamily A (Cys Cys) member 13 antibody; Small-inducible cytokine A13 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human CCL13
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
  • 基因功能參考文獻：
    1. CCL13 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. CCL13 levels in serum and synovial fluid may serve as a biomarker for the progression of osteoarthritis. PMID: 25654294
    3. CCL13 is an antimicrobial protein with bacteriocidal activity against E. coli. PMID: 12949249
    4. Data suggest that CCL13 binds to several chemokine receptors (CCR1, CCR2, and CCR3), allowing CCL13 to elicit different effects on target cells of immune system. CCL13 is involved in pathology of chronic inflammatory/autoimmune diseases. [REVIEW] PMID: 23846739
    5. MCP-4 and hsCRP may be the markers linking chronic inflammation in obesity and periodontal disease. PMID: 23375121
    6. E(2) has adverse effects on the pathogenesis of RA as a result of unregulated cell death, increased TNF-alpha-induced MMP-3 production, and CCL13 overproduction, subsequently resulting in the disease progression of RA. PMID: 22393877
    7. Findings suggest that the pro-atherogenic effects of CCR2 may not be restricted to interaction with MCP-1, but could also involve activation by MCP-4, being an inflammatory link between platelet and monocyte activation. PMID: 20139115
    8. Data suggest that the monocyte chemoattractant protein-4 core promoter YY-1 binding motif is functional, and modulates the transcriptional regulation of the MCP-4 gene. PMID: 12805085
    9. The study was undertaken to understand the relationship between the functional proteomics of receptor-Ck and developmental stages of human atherosclerotic aortic wall. PMID: 14560935
    10. MCP-4 may be a critical molecule that links obesity and chronic inflammation. PMID: 16855189
    11. The Th2 cytokine IL-4 preferentially stimulated MCP-4 expression. PMID: 17541284
    12. interferon-gamma with IL-1beta/TNF-alpha activates the production of CCL13 from chondrocytes in RA joints; secreted CCL13 enhances fibroblast-like synoviocyte proliferation by activating the extracellular signal-regulated MAP kinases cascade PMID: 17824960
    13. TLR2, 3, 4 and 5 ligands, but not TLR7/8 or 9 ligands, synergized with IL-4 to induce the production of MCP-4 in nasal polyp fibroblasts. PMID: 17851891
    14. CCL13 and HSPC159 mRNA expressions in PBMC are up-regulated specifically in MCNS patients during the nephrosis phase. PMID: 18219197
    15. Oncostatin M can strongly up-regulate the expression of CCL13, a chemokine recently identified in the synovial fluid of patients with rheumatoid arthritis. PMID: 19565514

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine beta (chemokine CC) family
  • 組織特異性：
    Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
  • 數據庫鏈接：

    HGNC: 10611

    OMIM: 601391

    KEGG: hsa:6357

    STRING: 9606.ENSP00000225844

    UniGene: Hs.414629



主站蜘蛛池模板： 全免费又大粗又黄又爽少妇片| 久久精品青青草原伊人| 国产女人水真多18毛片18精品| 无码日韩人妻精品久久蜜桃| 亚洲成在人线av无码| 97无码精品综合| 国产人成无码视频在线1000| 国产成人久久婷婷精品流白浆| 野狼第一精品社区| 国产精品女人呻吟在线观看| 久久精品日韩av无码| 精品深夜av无码一区二区| 天堂а√在线官网| 热の综合热の国产热の潮在线| 亚洲精品国产一区黑色丝袜| 久久五月精品中文字幕| 午夜在线a亚洲v天堂网2018| 国产又色又爽又黄的视频在线观看| 国产精品久久久久久久久久直播| 免费无码毛片一区二三区| 亚洲国产精品一区二区第四页| 日本一丰满一bbw| 国产精品久久久福利| 国精品无码一区二区三区在线蜜臀| 久久香蕉国产线看观看亚洲小说| 女人被爽到高潮视频免费国产| 亚洲综合国产成人丁香五月激情| 成人无码www在线看免费| av网站的免费观看| 亚洲中文字幕久久精品无码喷水| 加勒比一本heyzo高清视频| 小荡货奶真大水多好紧视频| 边喂奶边中出的人妻| 大陆熟妇丰满多毛xxxx| 亚洲红杏成在人线免费视频| 欧美亚洲日本日韩在线| 男女后进式猛烈xx00动态图片 | 久久成人国产精品无码| 国产精品厕所| 丰满熟妇人妻中文字幕 | 欧美黑人xxxx高潮猛交|