在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BRD3 Antibody

  • 中文名稱:
    BRD3兔多克隆抗體
  • 貨號:
    CSB-PA002801GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    BRD3
  • 別名:
    BRD 3 antibody; Brd3 antibody; BRD3_HUMAN antibody; Bromodomain containing 3 antibody; Bromodomain containing protein 3 antibody; Bromodomain-containing protein 3 antibody; KIAA0043 antibody; Open reading frame X antibody; ORFX antibody; RING3 like gene antibody; RING3-like protein antibody; RING3L antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human BRD3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.
  • 基因功能參考文獻:
    1. conclude that BRD3/4 and the FLT3-TAK1/NF-kB pathways collectively control a set of targets that are critically important for the survival of human MLL-AF9 cells PMID: 29240787
    2. The bromodomain and extraterminal domain (BET) family consists of BRDT, BRD2, BRD3, and BRD4, each containing 2 bromodomains located N-terminal to extraterminal domain, which is located near C-terminus. Data suggest that 10 distinct acylations participate in binding of BET family proteins to histone 4 (oligopeptide fragments used here); C-terminal bromodomains do not cooperatively bind multiple acylation sites. PMID: 28945351
    3. Ewing sarcoma may be susceptible to treatment with epigenetic inhibitors blocking BRD3/4 activity and the associated pathognomonic EWS-FLT1 transcriptional program. PMID: 26623725
    4. An isoform of BRD3, BRD3R (BRD3 with Reprogramming activity) is a reprogramming factor. PMID: 26947130
    5. Here, we identify NCT, a complex comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), casein kinase II (CKII), and several TAFs, as a regulator of condensin function. PMID: 24565511
    6. BRD2, BRD3, and BRD4 interact with gammaretroviral INs and serve as cofactors for murine leukemia virus integration. PMID: 24049186
    7. The BRDT gene was not expressed in testicular tissue from patients with Sertoli cells only, whereas the other three genes of the BET family retained expression in all the sperm pathologies. PMID: 22035730
    8. the structural basis for GATA1 and Brd3 interaction was described. PMID: 21555453
    9. Activated lymphocytes induced by mitogens or antigens express various sets of genes, including those involved in the expression of cytokines, surface molecules, and nuclear proteins. PMID: 12371535
    10. BRD-NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation. PMID: 17934517
    11. Results report that the double bromodomain proteins Brd2 and Brd3 associate preferentially in vivo with hyperacetylated chromatin along the entire lengths of transcribed genes. PMID: 18406326

    顯示更多

    收起更多

  • 相關疾?。?/div>
    A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 1104

    OMIM: 601541

    KEGG: hsa:8019

    STRING: 9606.ENSP00000305918

    UniGene: Hs.522472



主站蜘蛛池模板: 欧美亚洲日本国产综合在线| 狠狠综合久久av一区二区| 午夜视频在线瓜伦| 中文在线а√天堂| 暖暖 免费 高清 日本 在线 | 无码国内精品人妻少妇蜜桃视频| 色偷偷av男人的天堂| 欧美又大又粗午夜剧场免费| 亚洲精品乱码久久久久久日本麻豆 | 亚洲人成网站在线播放2019| 国产粉嫩小泬在线观看泬| 日韩免费人妻av无码专区蜜桃| 久久www免费人成_看片老司机| 亚洲国产精品综合久久20| 苍井空亚洲精品aa片在线播放| 特黄做受又大又粗又长大片| 亚洲va中文字幕无码一二三区| 337p日本欧洲亚洲大胆裸体艺术| 国产乱码人妻一区二区三区四区| 秋霞人妻无码中文字幕| 亚洲精品国偷自产在线99人热| 欧美真人性做爰全过程| 国内露脸中年夫妇交换| 蜜臀亚洲精品国产aⅴ综合第一| 精品婷婷色一区二区三区| 青青草国产三级精品三级| 在线中文字幕亚洲日韩2020| 国产精品美女被遭强扒开双腿| 玖玖资源站最稳定网址| 天天爽天天狠久久久综合麻豆| 国产精品99久久久久久久女警| 女人高潮被爽到呻吟在线观看| 丁香五月激情综合色婷婷| 少妇和邻居做不戴套视频| 久久久久久久久久久综合日本| 精品熟女少妇av免费观看| 久久久久久久久免费看无码| 国产高清-国产av| 免费看又色又爽又黄的国产软件| 内射口爆少妇麻豆| 永久免费的无码中文字幕|