在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BRD3 Antibody

BRD3 Antibody

  • 中文名稱：
    BRD3兔多克隆抗體
  • 貨號：
    CSB-PA001045
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of A549 cells using BRD3 Polyclonal Antibody
    • Western Blot analysis of RAT-MUSCLE cells using BRD3 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    BRD3
  • 別名：
    BRD 3 antibody; Brd3 antibody; BRD3_HUMAN antibody; Bromodomain containing 3 antibody; Bromodomain containing protein 3 antibody; Bromodomain-containing protein 3 antibody; KIAA0043 antibody; Open reading frame X antibody; ORFX antibody; RING3 like gene antibody; RING3-like protein antibody; RING3L antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human BRD3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.
  • 基因功能參考文獻：
    1. conclude that BRD3/4 and the FLT3-TAK1/NF-kB pathways collectively control a set of targets that are critically important for the survival of human MLL-AF9 cells PMID: 29240787
    2. The bromodomain and extraterminal domain (BET) family consists of BRDT, BRD2, BRD3, and BRD4, each containing 2 bromodomains located N-terminal to extraterminal domain, which is located near C-terminus. Data suggest that 10 distinct acylations participate in binding of BET family proteins to histone 4 (oligopeptide fragments used here); C-terminal bromodomains do not cooperatively bind multiple acylation sites. PMID: 28945351
    3. Ewing sarcoma may be susceptible to treatment with epigenetic inhibitors blocking BRD3/4 activity and the associated pathognomonic EWS-FLT1 transcriptional program. PMID: 26623725
    4. An isoform of BRD3, BRD3R (BRD3 with Reprogramming activity) is a reprogramming factor. PMID: 26947130
    5. Here, we identify NCT, a complex comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), casein kinase II (CKII), and several TAFs, as a regulator of condensin function. PMID: 24565511
    6. BRD2, BRD3, and BRD4 interact with gammaretroviral INs and serve as cofactors for murine leukemia virus integration. PMID: 24049186
    7. The BRDT gene was not expressed in testicular tissue from patients with Sertoli cells only, whereas the other three genes of the BET family retained expression in all the sperm pathologies. PMID: 22035730
    8. the structural basis for GATA1 and Brd3 interaction was described. PMID: 21555453
    9. Activated lymphocytes induced by mitogens or antigens express various sets of genes, including those involved in the expression of cytokines, surface molecules, and nuclear proteins. PMID: 12371535
    10. BRD-NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation. PMID: 17934517
    11. Results report that the double bromodomain proteins Brd2 and Brd3 associate preferentially in vivo with hyperacetylated chromatin along the entire lengths of transcribed genes. PMID: 18406326

    顯示更多

    收起更多

  • 相關疾?。?/div>
    A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 1104

    OMIM: 601541

    KEGG: hsa:8019

    STRING: 9606.ENSP00000305918

    UniGene: Hs.522472



主站蜘蛛池模板： www激情内射在线看| 国产在线精品一区在线观看| 露脸内射熟女--69xx| 农村欧美丰满熟妇xxxx| 日韩网红少妇无码视频香港 | 久久亚洲a片com人成| 小辣椒福利视频导航| 蜜臀av综合网| 国产成人无码a区在线观看视频app| 亚洲欧美黑人深喉猛交群| 亚洲成a∨人片在线观看不卡| 精品人妻少妇一区二区三区不卡 | 欧美成人精品福利视频| 香蕉啪视频在线观看视频久| 欧美最新精品videossexohd| 午夜男女爽爽影院免费视频下载| 久久人人爽人人爽人人av东京热 | 粗大的内捧猛烈进出视频| 99精品免费久久久久久久久日本| 女邻居的大乳中文字幕| 国内熟女啪啪自拍| 无码帝国www无码专区色综合 | 太粗太深了太紧太爽了动态图男男| 久本草在线中文字幕亚洲| 国产成人免费爽爽爽视频| 欧美人与动人物姣配xxxx| 久久久国产乱子伦精品| 国产欧美性成人精品午夜| 国产一区二区女内射| 亚洲国产精品13p| 亚洲 小说 欧美 另类 社区| 天堂中文官网在线| 国产精品99久久免费黑人人妻| 亚洲国产一卡2卡3卡4卡5公司 | 免费大片av手机看片不卡| 国产大陆亚洲精品国产| 国产精品高清一区二区三区| 中文乱码免费一区二区| 在线观看的av免费网站| 无码办公室丝袜ol中文字幕| 欧美亚洲国产精品久久高清|