在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BRD3 Antibody, HRP conjugated

BRD3 Antibody, HRP conjugated

  • 中文名稱：
    BRD3兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA624013HB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) BRD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    BRD3
  • 別名：
    BRD 3 antibody; Brd3 antibody; BRD3_HUMAN antibody; Bromodomain containing 3 antibody; Bromodomain containing protein 3 antibody; Bromodomain-containing protein 3 antibody; KIAA0043 antibody; Open reading frame X antibody; ORFX antibody; RING3 like gene antibody; RING3-like protein antibody; RING3L antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Bromodomain-containing protein 3 protein (356-506AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.
  • 基因功能參考文獻：
    1. conclude that BRD3/4 and the FLT3-TAK1/NF-kB pathways collectively control a set of targets that are critically important for the survival of human MLL-AF9 cells PMID: 29240787
    2. The bromodomain and extraterminal domain (BET) family consists of BRDT, BRD2, BRD3, and BRD4, each containing 2 bromodomains located N-terminal to extraterminal domain, which is located near C-terminus. Data suggest that 10 distinct acylations participate in binding of BET family proteins to histone 4 (oligopeptide fragments used here); C-terminal bromodomains do not cooperatively bind multiple acylation sites. PMID: 28945351
    3. Ewing sarcoma may be susceptible to treatment with epigenetic inhibitors blocking BRD3/4 activity and the associated pathognomonic EWS-FLT1 transcriptional program. PMID: 26623725
    4. An isoform of BRD3, BRD3R (BRD3 with Reprogramming activity) is a reprogramming factor. PMID: 26947130
    5. Here, we identify NCT, a complex comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), casein kinase II (CKII), and several TAFs, as a regulator of condensin function. PMID: 24565511
    6. BRD2, BRD3, and BRD4 interact with gammaretroviral INs and serve as cofactors for murine leukemia virus integration. PMID: 24049186
    7. The BRDT gene was not expressed in testicular tissue from patients with Sertoli cells only, whereas the other three genes of the BET family retained expression in all the sperm pathologies. PMID: 22035730
    8. the structural basis for GATA1 and Brd3 interaction was described. PMID: 21555453
    9. Activated lymphocytes induced by mitogens or antigens express various sets of genes, including those involved in the expression of cytokines, surface molecules, and nuclear proteins. PMID: 12371535
    10. BRD-NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation. PMID: 17934517
    11. Results report that the double bromodomain proteins Brd2 and Brd3 associate preferentially in vivo with hyperacetylated chromatin along the entire lengths of transcribed genes. PMID: 18406326

    顯示更多

    收起更多

  • 相關疾病：
    A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 1104

    OMIM: 601541

    KEGG: hsa:8019

    STRING: 9606.ENSP00000305918

    UniGene: Hs.522472



主站蜘蛛池模板： 天码欧美日本一道免费| 国产乱子经典视频在线观看| 尤物国产在线精品福利三区| 免费人成激情视频在线观看| 亚洲va在线∨a天堂va欧美va| 国产欠欠欠18一区二区| 久久九九久精品国产| 无码专区视频精品老司机| 色欲综合久久躁天天躁| 一 级 黄 色 片免费网站| 国精品无码一区二区三区在线| 国产在线高清亚洲精品二区| 亚洲人成日韩中文字幕无卡| 亚洲熟女乱综合一区二区| 全部av―极品视觉盛宴| 亚洲aⅴ在线无码播放毛片一线天| 国产激情高中生呻吟视频 | 农民人伦一区二区三区| аⅴ天堂中文在线网官网| 国产在线精品一区二区三区直播| 国产精品无码一区二区在线看| 免费中文熟妇在线影片| 国产偷人妻精品一区二区在线| 免费网禁国产you女网站下载| 国产精品亚洲а∨无码播放麻豆| 男女性色大片免费网站| 被灌满精子的波多野结衣| 婷婷五月综合色中文字幕 | 亚洲va中文字幕| 丰满少妇被粗大的猛烈进出视频| 色悠久久久久综合先锋影音下载 | 国产又大又黑又粗免费视频| 亚洲精品国精品久久99热| 欧美做受视频播放| 免费网站看sm调教视频| 51国产黑色丝袜高跟鞋| 精品午夜福利在线视在亚洲| av中文无码韩国亚洲色偷偷| 国产情侣久久久久aⅴ免费| 中文字幕卡二和卡三的视频| 国产精品自在拍首页视频|