在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BRD3 Antibody

BRD3 Antibody

  • 中文名稱：
    BRD3兔多克隆抗體
  • 貨號：
    CSB-PA624013HA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA624013HA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA624013HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) BRD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    BRD3
  • 別名：
    BRD 3 antibody; Brd3 antibody; BRD3_HUMAN antibody; Bromodomain containing 3 antibody; Bromodomain containing protein 3 antibody; Bromodomain-containing protein 3 antibody; KIAA0043 antibody; Open reading frame X antibody; ORFX antibody; RING3 like gene antibody; RING3-like protein antibody; RING3L antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Bromodomain-containing protein 3 protein (356-506AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，BRD3 Antibody (CSB-PA624013HA01HU)，的標記方式是Non-conjugated。對于BRD3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA624013HB01HU BRD3 Antibody, HRP conjugated ELISA
    FITC CSB-PA624013HC01HU BRD3 Antibody, FITC conjugated
    Biotin CSB-PA624013HD01HU BRD3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.
  • 基因功能參考文獻：
    1. conclude that BRD3/4 and the FLT3-TAK1/NF-kB pathways collectively control a set of targets that are critically important for the survival of human MLL-AF9 cells PMID: 29240787
    2. The bromodomain and extraterminal domain (BET) family consists of BRDT, BRD2, BRD3, and BRD4, each containing 2 bromodomains located N-terminal to extraterminal domain, which is located near C-terminus. Data suggest that 10 distinct acylations participate in binding of BET family proteins to histone 4 (oligopeptide fragments used here); C-terminal bromodomains do not cooperatively bind multiple acylation sites. PMID: 28945351
    3. Ewing sarcoma may be susceptible to treatment with epigenetic inhibitors blocking BRD3/4 activity and the associated pathognomonic EWS-FLT1 transcriptional program. PMID: 26623725
    4. An isoform of BRD3, BRD3R (BRD3 with Reprogramming activity) is a reprogramming factor. PMID: 26947130
    5. Here, we identify NCT, a complex comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), casein kinase II (CKII), and several TAFs, as a regulator of condensin function. PMID: 24565511
    6. BRD2, BRD3, and BRD4 interact with gammaretroviral INs and serve as cofactors for murine leukemia virus integration. PMID: 24049186
    7. The BRDT gene was not expressed in testicular tissue from patients with Sertoli cells only, whereas the other three genes of the BET family retained expression in all the sperm pathologies. PMID: 22035730
    8. the structural basis for GATA1 and Brd3 interaction was described. PMID: 21555453
    9. Activated lymphocytes induced by mitogens or antigens express various sets of genes, including those involved in the expression of cytokines, surface molecules, and nuclear proteins. PMID: 12371535
    10. BRD-NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation. PMID: 17934517
    11. Results report that the double bromodomain proteins Brd2 and Brd3 associate preferentially in vivo with hyperacetylated chromatin along the entire lengths of transcribed genes. PMID: 18406326

    顯示更多

    收起更多

  • 相關疾病：
    A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 1104

    OMIM: 601541

    KEGG: hsa:8019

    STRING: 9606.ENSP00000305918

    UniGene: Hs.522472



主站蜘蛛池模板： 性无码专区无码片| 女人被爽到高潮视频免费国产| 国产精品亚洲аv久久| 一区二区视频| 精品国产乱码久久久久久免费| 国内精品久久久久影院嫩草| 亚洲国产精品成人综合色| 免费的污污的网站在线观看| 少妇一边呻吟一边说使劲视频| 男女啪祼交视频| 少妇与子乱在线观看| 亚洲国产欧美中文丝袜日韩| 狠狠噜天天噜日日噜| 业余 自由 性别 成熟视频 视频| 奇米四色7777中文字幕| 天干天干啦夜天干天天爽| a在线视频v视频| 国产在线 | 中文| 亚洲国产精品尤物yw在线| 邪恶肉肉全彩色无遮盖| 少妇高潮大叫好爽| 亚洲精品喷潮一区二区三区 | 久久人妻无码aⅴ毛片a片app| 最近中文字幕mv在线视频看 | 久久精品国产国产精品四凭| 日本成本人片免费网站| 色窝窝无码一区二区三区| 国产 | 欧洲野花视频欧洲1| 亚洲欲色欲香天天综合网| 女人下边被添全过视频| 色综合天天综合网中文| 97无码免费人妻超级碰碰碰碰| 亚欧色一区w666天堂| 日韩欧美成人免费观看| 国产免费又色又爽又黄软件| 在线观看成人无码中文av天堂| 国产精品亲子乱子伦xxxx裸| 色一情一乱一伦一区二区三区小说 | 久久无码人妻一区二区三区午夜 | 成年无码av片在线| 婷婷网亚洲色偷偷男人的天堂|