在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Acetyl-HIST1H1E (K16) Antibody

Acetyl-HIST1H1E (K16) Antibody

  • 中文名稱：
    Acetyl-HIST1H1E (K16)兔多克隆抗體
  • 貨號：
    CSB-PA010380PA16acHU
  • 規格：
    ￥660
  • 圖片：
    • Immunocytochemistry analysis of MCF-7 cells using CSB-PA010380PA16acHU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells (sodium butyrate, 30 mM, 4h) using CSB-PA010380PA16acHU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Chromatin Immunoprecipitation Hela (4*106, treated with 30mM sodium butyrate for 4h) were treated with Micrococcal Nuclease, sonicated, and immunoprecipitated with 8µg anti-HIST1H1E (CSB-PA010380PA16acHU) or a control normal rabbit IgG. The resulting ChIP DNA was quantified using real-time PCR with primers against the β-Globin promoter.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Peptide sequence around site of Acetyl-Lys (16) derived from Human Histone H1.4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, ICC, IF, ChIP
  • 推薦稀釋比：
    Application Recommended Dilution
    ICC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病：
    Rahman syndrome (RMNS)
  • 亞細胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數據庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 天天天天躁天天爱天天碰| 掀开奶罩边吃边摸下娇喘视频| 2020最新无码国产在线观看| 中文字幕大看蕉在线观看| 亚洲老妈激情一区二区三区| 国产精品久久久久久一区二区三区 | 成人无码嫩草影院| 久久99精品久久久久久蜜芽| 国产一区日韩二区欧美三区| 日韩精品人妻中文字幕有码| 人妻三级日本香港三级极| 美女黄网站18禁免费看| 亚洲熟女乱色一区二区三区| 成人欧美日韩一区二区三区| 麻豆精品人妻一区二区三区蜜桃| 久久精品av国产一区二区| 亚洲色欲综合一区二区三区| 中文字幕无码人妻少妇免费| 亚洲色老汉av无码专区最| 成人伊人青草久久综合网| av在线播放日韩亚洲欧| 久久/这里只精品热在线获取| 欧美xxxxx在线观看| 青草青草视频2免费观看| 最新中文字幕av无码专区| 久久亚洲一区二区三区舞蹈| 精品无码国产日韩制服丝袜| 久久99精品久久只有精品| 嫩b人妻精品一区二区三区| 国产亚洲日韩在线aaaa| 亚洲人成人无码www影院 | 国产免费一区二区三区免费视频| 青青青国产在线观看免费| 丰满人妻熟妇乱又仑精品| 18禁黄污吃奶免费看网站| 国产成人啪精品视频免费网站软件| 成人无码午夜在线观看| 欧美va天堂在线电影| 又黄又爽又色的视频| 国产成人亚洲综合色婷婷秒播| 暖暖视频日本|