在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse C-C motif chemokine 4 protein (Ccl4)

In Stock
  • 中文名稱:
    Recombinant Mouse C-C motif chemokine 4 protein(Ccl4) (Active)
  • 貨號:
    CSB-AP001231MO
  • 規格:
    ¥2124
  • 圖片:
  • 其他:

產品詳情

  • 純度:
    >97% as determined by SDS-PAGE.
  • 內毒素:
    Less than 1.0 EU/μg as determined by LAL method.
  • 生物活性:
    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 20-100 ng/ml.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ccl4; Mip1b; Scya4; C-C motif chemokine 4; Immune activation protein 2; ACT-2; ACT2; Macrophage inflammatory protein 1-beta; MIP-1-beta; Protein H400; SIS-gamma; Small-inducible cytokine A4
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.Coli
  • 分子量:
    7.8 kDa
  • 表達區域:
    24-92aa
  • 氨基酸序列
    APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN
  • 蛋白標簽:
    Tag-Free
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    0.2 μm filtered 2X PBS, pH 7.4 ,lyophilized
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    5-10 business days
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Monokine with inflammatory and chemokinetic properties.
  • 基因功能參考文獻:
    1. CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity. PMID: 27177471
    2. YY1 regulates lung CCL4 transcription in pulmonary tuberculosis. PMID: 26786659
    3. Ccl4 mRNAs increased within 5 h after injury in mouse cortical slices. PMID: 25895671
    4. CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice PMID: 24244314
    5. CCL4 upregulation was associated with increased Snail expression and downregulation of p53/PTEN in high-grade PIN and prostate cancer PMID: 23878190
    6. These results suggest that MIP-1beta is a novel key mediator, and the peripheral MIP-1beta-CCR5 axis contributes to neuropathic pain. PMID: 22528550
    7. results indicate that MIP-1beta is involved in the recruitment of bone marrow-derived monocyte lineage cells PMID: 21912378
    8. increased responsiveness of murine eosinophils to MIP-1beta is mediated by CCR5 receptor in mice PMID: 12050188
    9. macrophage inflammatory protein-1beta is a hypoxia-induced neutrophil survival factor. PMID: 15630139
    10. MIP-1beta is overexpressed, and VE-cadherin is underexpressed in heart transplant allografts compared with isografts PMID: 15897346
    11. Overproduction of MIP-1beta in chemokine (C-C motif) receptor 5-deficient mice after collagen II-immunization may contribute partially to the occurrence of arthritis PMID: 15967376
    12. The expression and role CXCL12 and CCL4 and their receptors (CXCR4 and CCR5) in regulating thymocyte migration in conjunction with extracellular matrix during acute T. cruzi infection are investigated. PMID: 16637021
    13. ATF3 appears to be part of a control mechanism that limits the amount of CCL4 released by macrophages, preventing excessive inflammation. PMID: 16982098
    14. Antibody neutralization of CCL4 abrogates the ability of T-cells from IL-4-treated NOD mice to transfer protection against type 1 diabetes. PMID: 17327452

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine beta (chemokine CC) family
  • 數據庫鏈接:


主站蜘蛛池模板: 一本大道无码人妻精品专区| 亚洲国产成人精品无码区蜜柚| 色琪琪丁香婷婷综合久久| 国产无套精品一区二区| 色综合久久久久久久久久| 鲁丝片一区二区三区毛片| 久久精品成人免费观看| 精品国产天堂综合一区在线| 极品尤物一区二区三区| 中文字幕日本最新乱码视频| av国産精品毛片一区二区网站| 亚洲日韩色欲色欲com| 日本一区二区在线播放| 亚洲国产精品一区第二页| 在线看片免费人成视频在线影院| 国产成人精品自在线拍| 国内最真实的xxxx人伦| 国产内射999视频一区| 国产原创av中文在线观看| 国产成人青青久久大片| 国产真实乱对白精彩久久老熟妇女| 久久精品免视看国产成人明星 | 国产精品线路一线路二| 人妻少妇精品久久久久久| 国产乱对白刺激视频| 亚洲丁香婷婷综合久久| 久久精晶国产99久久6| 乱熟女高潮一区二区在线| 亚洲精品尤物av在线观看不卡| 亚洲一区二区三区高清在线看 | wwww亚洲熟妇久久久久| 狠狠色噜噜狠狠狠狠av不卡| 亚洲乱码中文论理电影| 国产日韩av在线播放| 无码人妻一区二区三区免费n鬼沢| 久久99热这里只有精品国产| 久久www免费人成_看片老司机| 久久久久成人网站| 久久久亚洲精品无码| 亚洲人成网站18禁止| 亚洲中文字幕无码中文字|