在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Mouse Macrophage Inflammatory Protein 1β,MIP-1β ELISA kit

Mouse Macrophage Inflammatory Protein 1β,MIP-1β ELISA kit

  • 中文名稱：
    小鼠巨噬細(xì)胞炎性蛋白1β(MIP-1β/CCL4)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-E04665m-IS
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3200/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    小鼠巨噬細(xì)胞炎性蛋白1β(MIP-1β/CCL4)酶聯(lián)免疫試劑盒（CSB-E04665m-IS）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織培養(yǎng)上清液、組織勻漿樣本中的CCL4含量。CCL4即趨化因子配體4，它在免疫調(diào)節(jié)等生理過(guò)程有重要作用。其背景與免疫細(xì)胞的募集和活化相關(guān)。研究機(jī)制方面，主要通過(guò)與相應(yīng)受體結(jié)合，引導(dǎo)免疫細(xì)胞遷移至炎癥或損傷部位，參與免疫反應(yīng)的調(diào)控，在感染、腫瘤等疾病研究中受關(guān)注。試劑盒檢測(cè)范圍為3.12 pg/mL-200 pg/mL，靈敏度為1.56 pg/mL。適用于體外研究炎癥反應(yīng)機(jī)制、免疫細(xì)胞遷移調(diào)控、疾病模型構(gòu)建等科研場(chǎng)景，可通過(guò)標(biāo)準(zhǔn)曲線精確分析樣本中MIP - 1β的動(dòng)態(tài)濃度變化，為探索趨化因子在免疫病理過(guò)程中的作用提供實(shí)驗(yàn)支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
  • 別名：
    Ccl4 ELISA Kit; Mip1b ELISA Kit; Scya4 ELISA Kit; C-C motif chemokine 4 ELISA Kit; Immune activation protein 2 ELISA Kit; ACT-2 ELISA Kit; ACT2 ELISA Kit; Macrophage inflammatory protein 1-beta ELISA Kit; MIP-1-beta ELISA Kit; Protein H400 ELISA Kit; SIS-gamma ELISA Kit; Small-inducible cytokine A4 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Mus musculus (Mouse)
  • 樣本類型：
    serum, plasma, cell culture supernates, tissue homogenates
  • 檢測(cè)范圍：
    3.12 pg/mL-200 pg/mL
  • 靈敏度：
    1.56 pg/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Immunology
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

  • 線性度：

    To assess the linearity of the assay, samples were spiked with high concentrations of mouse MIP-1β in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

    　

    Sample

    Serum(n=4)

    1:1

    Average %

    102

    Range %

    95-108

    1:2

    Average %

    96

    Range %

    91-102

    1:4

    Average %

    91

    Range %

    87-96

    1:8

    Average %

    90

    Range %

    86-96

  • 回收率：

    The recovery of mouse MIP-1β spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

    Sample Type

    Average % Recovery

    Range

    Serum (n=5)

    94

    88-98

    EDTA plasma (n=4)

    97

    91-103

  • 標(biāo)準(zhǔn)曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    pg/ml

    OD1

    OD2

    Average

    Corrected

    200

    2.483

    2.634

    2.558

    2.386

    100

    1.530

    1.617

    1.574

    1.401

    50

    1.009

    0.957

    0.983

    0.811

    25

    0.557

    0.529

    0.543

    0.371

    12.5

    0.350

    0.331

    0.340

    0.168

    6.25

    0.244

    0.253

    0.249

    0.076

    3.12

    0.196

    0.184

    0.190

    0.018

    0

    0.177

    0.168

    0.172

    　

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Monokine with inflammatory and chemokinetic properties.
  • 基因功能參考文獻(xiàn)：
    1. CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity. PMID: 27177471
    2. YY1 regulates lung CCL4 transcription in pulmonary tuberculosis. PMID: 26786659
    3. Ccl4 mRNAs increased within 5 h after injury in mouse cortical slices. PMID: 25895671
    4. CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice PMID: 24244314
    5. CCL4 upregulation was associated with increased Snail expression and downregulation of p53/PTEN in high-grade PIN and prostate cancer PMID: 23878190
    6. These results suggest that MIP-1beta is a novel key mediator, and the peripheral MIP-1beta-CCR5 axis contributes to neuropathic pain. PMID: 22528550
    7. results indicate that MIP-1beta is involved in the recruitment of bone marrow-derived monocyte lineage cells PMID: 21912378
    8. increased responsiveness of murine eosinophils to MIP-1beta is mediated by CCR5 receptor in mice PMID: 12050188
    9. macrophage inflammatory protein-1beta is a hypoxia-induced neutrophil survival factor. PMID: 15630139
    10. MIP-1beta is overexpressed, and VE-cadherin is underexpressed in heart transplant allografts compared with isografts PMID: 15897346
    11. Overproduction of MIP-1beta in chemokine (C-C motif) receptor 5-deficient mice after collagen II-immunization may contribute partially to the occurrence of arthritis PMID: 15967376
    12. The expression and role CXCL12 and CCL4 and their receptors (CXCR4 and CCR5) in regulating thymocyte migration in conjunction with extracellular matrix during acute T. cruzi infection are investigated. PMID: 16637021
    13. ATF3 appears to be part of a control mechanism that limits the amount of CCL4 released by macrophages, preventing excessive inflammation. PMID: 16982098
    14. Antibody neutralization of CCL4 abrogates the ability of T-cells from IL-4-treated NOD mice to transfer protection against type 1 diabetes. PMID: 17327452

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine beta (chemokine CC) family
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 欧美三级a做爰在线观看| 国产精品久久久久久日本| 国产亚洲精品一区二三区| 精品无人乱码高清在线观看| 久久国产精品成人片免费| 亚洲精品一区二区久| 九九九国产精品成人免费视频 | 欧美一区二区三区性视频| 国产传媒精品1区2区3区| 亚洲 欧美 中文 在线 视频| 香港三级日本三级妇三级| 国产有奶水哺乳期无码avav| 亚在线第一国产州精品99| 国产精品自在在线午夜免费| 亚洲性啪啪无码av天堂| 亚欧成a人无码精品va片| 中文字幕人妻av一区二区| 奇米影视7777狠狠狠狠影视| 欧美疯狂做受xxxx高潮 | 色又黄又爽18禁免费视频| 欲香欲色天天综合久久| 一道久在线无码加勒比| 激情综合色综合啪啪五月丁香 | 久久久精品久久日韩一区综合 | 久久综合亚洲色一区二区三区| 香港三级日本三级a视频| 中日韩精品卡一卡二卡3卡| 国产乱了伦视频大全亚琴影院| 天天摸天天碰天天添| 成年片色大黄全免费软件到| 人妻激情乱人伦| 农村老熟妇乱子伦视频| 亚洲国产av无码精品无广告| 国产天美传媒性色av出轨| 800av凹凸视频在线观看| 国产精品无码一区二区三区电影 | 人与禽性视频77777| 学生妹无套内射正在播放 | 四虎亚洲中文字幕无码永久 | 娇小萝被两个黑人用半米长| 国内揄拍国内精品人妻浪潮av|