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SYNGAP1

Ras/Rap GTPase-activating protein SynGAP is a protein in humans that is encoded by SYNGAP1 gene. Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).

SYNGAP1 Antibodies

SYNGAP1 for Homo sapiens (Human)

SYNGAP1 Proteins

SYNGAP1 Proteins for Mus musculus (Mouse)

SYNGAP1 Proteins for Homo sapiens (Human)

SYNGAP1 Proteins for Rattus norvegicus (Rat)