HAVCR1
HAVCR1，全稱為hepatitis A virus cellular receptor 1，常見別名包括TIM-1和HAVCR1。該蛋白是一種Ⅰ型黏蛋白樣整合膜糖蛋白，在甲型肝炎病毒（HAV）的感染過程中扮演關(guān)鍵角色。HAVCR1作為HAV的受體，介導(dǎo)病毒與肝細(xì)胞的結(jié)合，進(jìn)而促進(jìn)病毒進(jìn)入細(xì)胞內(nèi)部。此外，HAVCR1還參與調(diào)節(jié)免疫反應(yīng)，影響炎癥和免疫調(diào)節(jié)過程。在疾病方面，HAVCR1與甲型肝炎的發(fā)病機(jī)制密切相關(guān)，同時(shí)也是寨卡病毒感染胎盤的關(guān)鍵靶點(diǎn)，與母嬰傳播密切相關(guān)。近年來，HAVCR1已成為藥物研發(fā)的重要靶點(diǎn)，針對(duì)該蛋白的抑制劑被開發(fā)用于阻斷病毒感染和疾病治療。例如，研究表明HAVCR1抑制劑可以有效阻止寨卡病毒感染胎盤，為預(yù)防先天性寨卡綜合征提供了新的治療策略。此外，HAVCR1在哮喘和過敏性疾病的發(fā)病機(jī)制中也發(fā)揮作用，相關(guān)藥物研發(fā)正在進(jìn)行中。
熱銷產(chǎn)品
Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (CSB-MP010144HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HAVCR1 Recombinant Monoclonal Antibody (CSB-RA974628A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: 293T whole cell lysate(30μg), NIH/3T3 whole cell lysate(30μg), JK whole cell lysate(30μg), MCF7 whole cell lysate(30μg), Hela whole cell lysate(30μg)
All lanes: HAVCR1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 50-55 kDa
Observed band size: 55 kDa
Exposure time：10s
Human Kidney injury molecule 1,Kim-1 ELISA Kit (CSB-E08807h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E08807h
規(guī)格：96T/48T
靈敏度：0.043 ng/mL
檢測范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
HAVCR1 Antibodies
HAVCR1 for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA17109A0Rb | Havcr1 Antibody | Mouse | ELISA, IHC |
HAVCR1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA09995A0Rb | HAVCR1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA090386 | HAVCR1 Antibody | Human | ELISA,IHC |
| CSB-PA913997 | HAVCR1 Antibody | Human | ELISA,WB |
| CSB-RA974628A0HU | HAVCR1 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB |
| CSB-RA010144MA1HU | HAVCR1 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
HAVCR1 Proteins
HAVCR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010144RA1 CSB-EP010144RA1 CSB-BP010144RA1 CSB-MP010144RA1 CSB-EP010144RA1-B |
Recombinant Rat Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010144RA | Recombinant Rat Hepatitis A virus cellular receptor 1 homolog (Havcr1) | in vitro E.coli expression system |
HAVCR1 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010144DSU1 CSB-EP010144DSU1 CSB-BP010144DSU1 CSB-MP010144DSU1 CSB-EP010144DSU1-B |
Recombinant Chlorocebus aethiops Hepatitis A virus cellular receptor 1 (HAVCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010144DSU | Recombinant Chlorocebus aethiops Hepatitis A virus cellular receptor 1 (HAVCR1) | in vitro E.coli expression system |
HAVCR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010144HU CSB-EP010144HU CSB-BP010144HU CSB-EP010144HU-B |
Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP010144HU | Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial | Mammalian cell |
HAVCR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP735580MO CSB-EP735580MO CSB-BP735580MO CSB-MP735580MO CSB-EP735580MO-B |
Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP735580MO | Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial | E.coli |
HAVCR1 ELISA Kit
HAVCR1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08807h | Human Kidney injury molecule 1,Kim-1 ELISA Kit | serum, urine, tissue homogenates | 0.043 ng/mL |
HAVCR1 ELISA Kit for Monkey
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL010144RH | Monkey hepatitis A virus cellular receptor 1/KIM1(HAVCR1) ELISA kit | serum, urine | 0.078 ng/mL |
HAVCR1 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08809m | Mouse Kidney injury molecule 1,Kim-1 ELISA Kit | serum, plasma, tissue homogenates, urine | 0.225 ng/mL |
HAVCR1 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08808r | Rat Kidney injury molecule 1,Kim-1 ELISA Kit | serum, plasma, urine | 0.228 ng/mL |
