GABRB1
GABRB1,即γ-氨基丁酸A型受體亞基beta1,別名DEE45、EIEE45等。它位于人類第4號染色體的4p12區域,屬于GABA受體家族中的一員。GABRB1的作用機制是通過與GABA結合,調節氯離子通道的開啟,導致神經元細胞膜的超極化,從而降低神經元的興奮性,產生抑制性突觸后電位。GABRB1在中樞神經系統中調節最快的抑制性突觸傳遞,對于維持神經系統的正常功能至關重要。其變異與精神分裂癥的病理學有關,并可能與癲癇、酒精依賴、雙相情感障礙等疾病的發生發展相關。
熱銷產品
GABRB1 Antibody (CSB-PA554723)
驗證數據

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA554723(GABRB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA554723(GABRB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
GABRB1 Antibodies
GABRB1 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA009146GA01HU | GABRB1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA620050 | GABRB1 (Ab-434) Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA000669 | Phospho-GABRB1 (S434) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA008556 | GABRB1 Antibody | Human,Mouse,Rat | IHC, ELISA |
CSB-PA554723 | GABRB1 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA086437 | GABRB1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
GABRB1 Proteins
GABRB1 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP009146HU CSB-EP009146HU CSB-BP009146HU CSB-MP009146HU CSB-EP009146HU-B |
Recombinant Human Gamma-aminobutyric acid receptor subunit beta-1 (GABRB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |