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CNGA3

Cyclic nucleotide-gated cation channel alpha-3 is a protein in humans that is encoded by CNGA3 gene. Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

CNGA3 Antibodies

CNGA3 for Homo sapiens (Human)

CNGA3 Proteins

CNGA3 Proteins for Homo sapiens (Human)

CNGA3 Proteins for Bos taurus (Bovine)

CNGA3 Proteins for Mus musculus (Mouse)



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