CDH17
CDH17,即鈣粘蛋白17,別名LI-cadherin。CDH17是一種7D-cadherin家族的成員,其胞外域由EC1-EC7七個重復序列構成,胞內域含18-20個氨基酸。CDH17的功能是作為多肽轉運器和細胞粘附分子來維持上皮組織的完整性。CDH17的粘附機制與典型cadherin不同,它不需要與α和β-catenins復合,能在不與其他細胞質成分相互作用的情況下保持粘合功能。CDH17在正常人類細胞中僅在小腸和結腸中高表達,而在肝臟、心臟和腎臟等其他組織中不表達或低表達。然而,在腫瘤組織中,CDH17在胃、胰腺、肝、食道、膽管癌和結直腸癌中過表達,其表達異常與腫瘤的形成和轉移密切相關。CDH17是消化系統惡性腫瘤的潛在診斷標志物和治療靶點。
熱銷產品
Recombinant Human Cadherin-17 (CDH17), partial (Active) (CSB-MP613267HU)
驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 2μg/mL can bind Anti-CDH17 recombinant antibody (CSB-RA613267MA1HU), the EC50 is 3.095 to 4.451 ng/mL.
Recombinant Macaca fascicularis Cadherin 17 (CDH17), partial (Active) (CSB-MP4664MOV)
驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CDH17 at 2μg/mL can bind Anti-CDH17 antibody, the EC50 is 4.666-5.447 ng/mL
CDH17 Recombinant Monoclonal Antibody (CSB-RA613267MA1HU)
驗證數據

The Binding Activity of Human CDH17 with Anti-CDH17 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 (CSB-MP613267HU) at 2 μg/mL can bind Anti-CDH17 recombinant antibody, the EC50 is 3.095-4.451 ng/mL.

Untransfected HEK293T cells surface (green line) and transfected Human CDH17 HEK293T stable cells surface (red line) were stained with anti-CDH17 antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
CDH17 Antibodies
CDH17 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA613267ESR1HU | CDH17 Antibody | Human | ELISA, IHC |
CSB-PA212083 | CDH17 Antibody | Human | ELISA,WB,IF |
CSB-PA006407 | CDH17 Antibody | Human | WB, IHC, IF, ELISA |
CSB-PA017530LA01HU | PCDH17 Antibody | Human | ELISA, IF |
CSB-PA017530LD01HU | PCDH17 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA017530LC01HU | PCDH17 Antibody, FITC conjugated | Human | |
CSB-PA017530LB01HU | PCDH17 Antibody, HRP conjugated | Human | ELISA |
CSB-RA613267MA1HU | CDH17 Recombinant Monoclonal Antibody | Human | ELISA, FC |
CDH17 Proteins
CDH17 Proteins for Rattus norvegicus (Rat)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP005042RA CSB-EP005042RA CSB-BP005042RA CSB-EP005042RA-B |
Recombinant Rat Cadherin-17 (Cdh17), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CDH17 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP017530HU CSB-EP017530HU CSB-BP017530HU CSB-MP017530HU CSB-EP017530HU-B |
Recombinant Human Protocadherin-17 (PCDH17), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP613267HU CSB-BP613267HU CSB-EP613267HU-B |
Recombinant Human Cadherin-17 (CDH17), partial | E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP613267HU | Recombinant Human Cadherin-17 (CDH17), partial (Active) | Mammalian cell |
CDH17 Proteins for Mus musculus (Mouse)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-BP882608MO CSB-MP882608MO CSB-EP882608MO-B |
Recombinant Mouse Cadherin-17 (Cdh17), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP882608MO | Recombinant Mouse Cadherin-17 (Cdh17), partial | E.coli |
CSB-YP882608MO | Recombinant Mouse Cadherin-17 (Cdh17), partial | Yeast |
CSB-MP882608MO1 | Recombinant Mouse Cadherin-17 (Cdh17), partial | Mammalian cell |