在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protocadherin-17 (PCDH17), partial

Recombinant Human Protocadherin-17 (PCDH17), partial

  • 中文名稱：
    人PCDH17重組蛋白
  • 貨號：
    CSB-YP017530HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PCDH17重組蛋白
  • 貨號：
    CSB-EP017530HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PCDH17重組蛋白
  • 貨號：
    CSB-EP017530HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PCDH17重組蛋白
  • 貨號：
    CSB-BP017530HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PCDH17重組蛋白
  • 貨號：
    CSB-MP017530HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PCDH17
  • Uniprot No.：
  • 別名：
    C030033F14Rik; Gm78; PCD17_HUMAN; PCDH17; PCDH68; PCH68; Protocadherin 17; Protocadherin 68; Protocadherin-17; Protocadherin-68
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Potential calcium-dependent cell-adhesion protein.
  • 基因功能參考文獻：
    1. Methylation of PCDH17 could play an important role in development and progression of high-grade serous ovarian carcinoma (HGSOC)and has potential to become a target in the search for new clinical biomarkers PMID: 29991130
    2. PCDH17 methylation in serum is a potential prognostic biomarker for patients with renal cell carcinoma after surgery. PMID: 28688232
    3. PCDH17 functions as a tumor suppressor inhibiting Wnt/beta-catenin signaling and metastasis in breast cancer but is frequently methylated in primary tumors which could be a potential biomarker. PMID: 27351130
    4. Aberrant methylation of protocadherin 17 is associated with acute lymphoblastic leukemia. PMID: 27643535
    5. PCDH-17 inhibited metastasis via EGFR/MEK/ERK signaling pathway. PMID: 26386721
    6. DNA methylation in a combination of POU4F2/PCDH17 has yielded the highest sensitivity and specificity of 90.00% and 93.96% in all the 312 individuals, showing the capability of detecting bladder cancer effectively among pathologically varied sample groups. PMID: 26700620
    7. PCDH17 methylation in serum is a frequent event in early-stage prostate cancer, and it is an independent predictor of BCR after radical prostatectomy PMID: 26683656
    8. PCDH17 methylation occurred more frequently and was associated with malignant clinicopathological characteristics and poor prognosis in clear cell renal cell carcinoma patients PMID: 26404644
    9. PCDH17 promoter methylation is closely associated with bladder cancer malignancy and may be used as an independent predictor of clinical outcomes in patients with bladder cancer. PMID: 24567353
    10. PCDH17 promoter methylation was significantly associated with malignant behaviour and poor prognosis of bladder cancer PMID: 24366498
    11. This study demonistrated that critical role for PCDH17 in the synaptic development of specific corticobasal ganglia circuits and suggest the involvement of PCDH17 in such circuits in depressive behaviors. PMID: 23684785
    12. PCDH17 acts as a tumour suppressor, exerting its anti-proliferative activity through inducing apoptosis and autophagy, and is frequently silenced in gastric and colorectal cancers. PMID: 22926751
    13. Our study clearly demonstrates that PCDH17 is transcriptionally downregulated in gastric cancer due to aberrant promoter CpG island methylation PMID: 22207556
    14. statistical significant downregulation of PCDH17/PCH68 and PTPRD was observed PMID: 21213369
    15. results suggest that silencing of PCDH17 expression through hypermethylation of the promoter or other mechanisms leads to loss of its tumour-suppressive activity, which may be a factor in the carcinogenesis of a subgroup of ESCCs PMID: 20200074
    16. Azoospermic testis showed down-regulation of CDH18 and PCDH17. PMID: 20180417
    17. the apparent occurrence of an unusual TG 3' splice site in intron 2 is discussed PMID: 17672918

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 數據庫鏈接：

    HGNC: 14267

    OMIM: 611760

    KEGG: hsa:27253

    UniGene: Hs.106511



主站蜘蛛池模板： 亚洲色欲色欱www在线| 狠狠色噜噜狠狠狠777米奇888| 377p欧洲日本亚洲大胆| 扒开双腿疯狂进出爽爽爽| 四虎永久在线精品免费网址| 4480yy私人精品国产| 亚洲高清国产拍精品闺蜜合租| 国产免费观看久久黄av片| 国产成人av一区二区三区| 日韩人妻无码精品免费shipin| 久久综合少妇11p| 国产精品成人99久久久久| 国内a∨免费播放| 嫩b人妻精品一区二区三区| 日韩美女自卫慰黄网站| 综合激情五月综合激情五月激情1| 亚洲久久久久久中文字幕| 少妇性饥渴无码a区免费| 日韩av无码成人无码免费| 天堂岛国av无码免费无禁网站| 色综合天天综合网国产成人网 | 国产午夜三级一区二区三| 超碰97人人做人人爱亚洲尤物| 2019最新中文字幕在线观看| 国产日韩一区二区三免费高清| 久久亚洲精品无码网站| 天干天干夜啦天干天干国产 | 日本熟妇人妻xxxxx-欢迎您| 国产高清在线a免费视频观看| 久久久国产打桩机| 婷婷久久香蕉五月综合| 国产69精品久久久久孕妇| 色悠久久久久久久综合网| 日本高清视频www夜色资源| 国产成人影院一区二区三区| 亚洲国内成人精品网| 久久综合给合久久狠狠狠97色| 成人毛片无码免费播放网站| 中文字幕亂倫免賛視頻| 男人猛吃奶女人爽视频| 国产免费一区二区视频|