在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human WD repeat-containing protein 34 (WDR34)

  • 中文名稱:
    人WDR34重組蛋白
  • 貨號:
    CSB-YP842668HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人WDR34重組蛋白
  • 貨號:
    CSB-EP842668HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人WDR34重組蛋白
  • 貨號:
    CSB-EP842668HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人WDR34重組蛋白
  • 貨號:
    CSB-BP842668HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人WDR34重組蛋白
  • 貨號:
    CSB-MP842668HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    WDR34
  • Uniprot No.:
  • 別名:
    bA216B9.3; DIC5; MGC20486; OTTHUMP00000022282; RP11 216B9.5; WD repeat containing protein 34; WD repeat domain 34; WD repeat-containing protein 34; WDR 34; Wdr34; WDR34_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-536
  • 氨基酸序列
    MATRAQPGPL SQAGSAGVAA LATVGVASGP GPGRPGPLQD ETLGVASVPS QWRAVQGIRW ETKSCQTASI ATASASAQAR NHVDAQVQTE APVPVSVQPP SQYDIPRLAA FLRRVEAMVI RELNKNWQSH AFDGFEVNWT EQQQMVSCLY TLGYPPAQAQ GLHVTSISWN STGSVVACAY GRLDHGDWST LKSFVCAWNL DRRDLRPQQP SAVVEVPSAV LCLAFHPTQP SHVAGGLYSG EVLVWDLSRL EDPLLWRTGL TDDTHTDPVS QVVWLPEPGH SHRFQVLSVA TDGKVLLWQG IGVGQLQLTE GFALVMQQLP RSTKLKKHPR GETEVGATAV AFSSFDPRLF ILGTEGGFPL KCSLAAGEAA LTRMPSSVPL RAPAQFTFSP HGGPIYSVSC SPFHRNLFLS AGTDGHVHLY SMLQAPPLTS LQLSLKYLFA VRWSPVRPLV FAAASGKGDV QLFDLQKSSQ KPTVLIKQTQ DESPVYCLEF NSQQTQLLAA GDAQGTVKVW QLSTEFTEQG PREAEDLDCL AAEVAA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone.; Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.
  • 基因功能參考文獻:
    1. In addition to the in vitro experiments, WDR34 negativity was correlated with tumoral growth of OSCCs. Our findings suggested that WDR34 inhibits OSCC progression and might be a potential tumor-suppressor molecule in OSCCs. PMID: 29278705
    2. In patients with short-rib polydactyly syndrome type III, primary cilia in WDR34 mutant fibroblasts were significantly shorter than normal and had a bulbous tip. PMID: 24183449
    3. Mutations in WDR34 cause Jeune asphyxiating thoracic dystrophy. WDR34 is critical for ciliary functions essential to normal development and survival. PMID: 24183451
    4. Results suggest that WDR34 is a TAK1-associated inhibitor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway. PMID: 19521662
  • 相關疾病:
    Short-rib thoracic dysplasia 11 with or without polydactyly (SRTD11)
  • 亞細胞定位:
    Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cell projection, filopodium.
  • 組織特異性:
    Expressed in several cell lines (at protein level).
  • 數據庫鏈接:

    HGNC: 28296

    OMIM: 613363

    KEGG: hsa:89891

    STRING: 9606.ENSP00000361800

    UniGene: Hs.495240



主站蜘蛛池模板: 午夜天堂一区人妻| 亚洲大码熟女在线观看| 日韩在线看片免费人成视频播放| 欧美性猛交xxxx黑人猛交 | 一級特黃色毛片免費看| 国产一卡2卡3卡4卡网站精品| 一区二区国产精品精华液| 天天天天做夜夜夜夜做无码| 午夜成人亚洲理论片在线观看| 精品人妻无码一区二区三区蜜桃一| 国产乱来乱子视频| 黑色丝袜脚足国产在线看| 国产99久久久国产无需播放器 | 成年女人免费碰碰视频| 欧美金妇欧美乱妇xxxx| 午夜视频在线在免费| 亚洲成 人 综合 亚洲欧洲| 无遮挡又黄又刺激的视频| 国产av激情无码久久| 国产精品美女久久久久久2021| 人妻无码精品久久亚瑟影视| 宅宅少妇无码| 三级做a全过程在线观看| 人人爽人人添人人超| 中文字幕 制服 亚洲 另类| 校园春色~综合网| 不卡无码人妻一区三区音频| 中文字幕中文乱码www| 邻居少妇张开双腿让我爽一夜| 午夜福利理论片高清在线| 高潮射精日本韩国在线播放| 国产精品久久久久久av| 欧美国产日产一区二区| 少妇人妻中文字幕hd| 欧美熟妇性xxx交潮喷| 国产精品久久久久av福利动漫| 亚洲欧美日韩中字视频三区| 日本免费一区二区三区四区五区| 少妇人妻系列无码专区视频| a∨变态另类天堂无码专区| 久久人人97超碰caoporen|