在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Transcriptional repressor NF-X1 (NFX1), partial

Recombinant Human Transcriptional repressor NF-X1 (NFX1), partial

  • 中文名稱：
    人NFX1重組蛋白
  • 貨號：
    CSB-YP621527HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NFX1重組蛋白
  • 貨號：
    CSB-EP621527HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NFX1重組蛋白
  • 貨號：
    CSB-EP621527HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NFX1重組蛋白
  • 貨號：
    CSB-BP621527HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NFX1重組蛋白
  • 貨號：
    CSB-MP621527HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NFX1
  • Uniprot No.：
  • 別名：
    NFX1; NFX2; Transcriptional repressor NF-X1; EC 2.3.2.-; Nuclear transcription factor; X box-binding protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
  • 基因功能參考文獻：
    1. This study identifies NFX1-123 as a critical host protein partner through which 16E6 is able to subvert the immune response and in turn permit a long-lived high-risk Human papillomavirus infection. PMID: 29117186
    2. The results showed that a repressor complex composed of NFX1-91, mSin3A and histone deacetylase 1 was involved in the PKC-delta-induced repression of the hTERT promoter, which resulted in the repression of hTERT transcription. PMID: 27311997
    3. Human papillomavirus 16 E6 (16E6) interacts with the cellular protein NFX1-123, and they collaboratively increase the growth and differentiation master regulator, Notch1. PMID: 25723053
    4. NFX1-123 and human papillomavirus 16E6 upregulated Notch 1 expression in keratinocytes. PMID: 24109236
    5. HuD acts as a novel adaptor protein to recruit TAP for efficient export of ARE-containing mRNAs in neuronal cells PMID: 15358174
    6. the induction of hTERT telomerase by the HPV-16 E6/E6-AP complex involves targeting of NFX1-91, a newly identified repressor of telomerase, for ubiquitination and degradation. PMID: 15371341
    7. Nrf1 is normally targeted to the endoplasmic reticulum membrane and endoplasmic reticulum stress may play a role in modulating Nrf1 function as a transcriptional activator PMID: 16687406
    8. data suggest that NFX1-123 is integral to hTERT regulation in HPV16 E6-expressing epithelial cells and that the interaction between NFX1-123 and poly(A) binding proteins is critical to hTERT activity PMID: 17267499
    9. These data demonstrate that targeted degradation of NFX1-91 by E6/E6AP dissociates the mSin3A/HDAC complex from the hTERT promoter and induces hTERT transcription. PMID: 18505829
    10. NFX1-123 is a cytoplasmic protein that colocalizes with poly(A) binding proteins, and binds hTERT mRNA in HPV16 E6-expressing keratinocytes. PMID: 19369336

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NFX1 family
  • 數據庫鏈接：

    HGNC: 7803

    OMIM: 603255

    KEGG: hsa:4799

    STRING: 9606.ENSP00000368856

    UniGene: Hs.413074



主站蜘蛛池模板： 午夜福利av无码一区二区| 日日做夜狠狠爱欧美黑人| 97人人添人澡人人爽超碰| 亚洲综合激情七月婷婷| 中文字幕在线播放| 性按摩xxxx在线观看| av一区二区三区人妻少妇| 欧美人妻久久精品| 亚洲精品四区麻豆文化传媒| 色欲综合久久中文字幕网| 国产精品丰臀| …日韩人妻无码精品一专区| 毛片tv网站无套内射tv网站| 曰本一道本久久88不卡| 国产超碰人人做人人爽av大片| 97夜夜澡人人爽人人| 日韩人妻无码一区二区三区| 国产精品青青在线观看爽香蕉| 免费无码av片在线观看国产| 99精品国产高清一区二区麻豆| 爆乳2把你榨干哦ova在线观看| 亚洲a∨国产av综合av下载| 成人网站免费大全日韩国产 | 精品无码一区二区三区在线| 国产精品vⅰdeoxxxx国产| 色综合久久久久综合99| 无码熟熟妇丰满人妻porn| 亚洲色大成网站www永久男同 | 337p日本欧洲亚洲大胆| 少妇一夜三次一区二区| 色猫咪免费人成网站在线观看| 久久天天躁狠狠躁夜夜2019| 内射国产内射夫妻免费频道| 久久久无码精品午夜| 无码人妻丝袜视频在线播免费 | 成人看的污污超级黄网站免费| 国产高清-国产av| 欧美做受又硬又粗又大视频| 欧美va亚洲va在线观看| 四虎永久在线精品免费视频观看| 亚洲欧美人高清精品a∨|