在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NFX1 Antibody

NFX1 Antibody

  • 中文名稱：
    NFX1兔多克隆抗體
  • 貨號：
    CSB-PA015771GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    NFX1
  • 別名：
    NFX1 antibody; NFX2 antibody; Transcriptional repressor NF-X1 antibody; EC 2.3.2.- antibody; Nuclear transcription factor antibody; X box-binding protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NFX1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
  • 基因功能參考文獻：
    1. This study identifies NFX1-123 as a critical host protein partner through which 16E6 is able to subvert the immune response and in turn permit a long-lived high-risk Human papillomavirus infection. PMID: 29117186
    2. The results showed that a repressor complex composed of NFX1-91, mSin3A and histone deacetylase 1 was involved in the PKC-delta-induced repression of the hTERT promoter, which resulted in the repression of hTERT transcription. PMID: 27311997
    3. Human papillomavirus 16 E6 (16E6) interacts with the cellular protein NFX1-123, and they collaboratively increase the growth and differentiation master regulator, Notch1. PMID: 25723053
    4. NFX1-123 and human papillomavirus 16E6 upregulated Notch 1 expression in keratinocytes. PMID: 24109236
    5. HuD acts as a novel adaptor protein to recruit TAP for efficient export of ARE-containing mRNAs in neuronal cells PMID: 15358174
    6. the induction of hTERT telomerase by the HPV-16 E6/E6-AP complex involves targeting of NFX1-91, a newly identified repressor of telomerase, for ubiquitination and degradation. PMID: 15371341
    7. Nrf1 is normally targeted to the endoplasmic reticulum membrane and endoplasmic reticulum stress may play a role in modulating Nrf1 function as a transcriptional activator PMID: 16687406
    8. data suggest that NFX1-123 is integral to hTERT regulation in HPV16 E6-expressing epithelial cells and that the interaction between NFX1-123 and poly(A) binding proteins is critical to hTERT activity PMID: 17267499
    9. These data demonstrate that targeted degradation of NFX1-91 by E6/E6AP dissociates the mSin3A/HDAC complex from the hTERT promoter and induces hTERT transcription. PMID: 18505829
    10. NFX1-123 is a cytoplasmic protein that colocalizes with poly(A) binding proteins, and binds hTERT mRNA in HPV16 E6-expressing keratinocytes. PMID: 19369336

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NFX1 family
  • 數據庫鏈接：

    HGNC: 7803

    OMIM: 603255

    KEGG: hsa:4799

    STRING: 9606.ENSP00000368856

    UniGene: Hs.413074



主站蜘蛛池模板： 色yeye香蕉凹凸视频在线观看 | 国产成人毛片在线视频软件| 99热国产这里只有精品6| 欧美黑吊大战白妞| 老熟妇仑乱一区二区视頻| 国产第一页屁屁影院| 人人做人人爽久久久精品| 中国猛少妇色xxxxx| 国产白嫩美女在线观看| 色综合久久中文娱乐网| 亚洲成av人片天堂网老年人| 伊人婷婷六月狠狠狠去| 亚洲日韩中文字幕无码一区| 久久九九久精品国产日韩经典| 成 人 a v免费视频在线观看| 曰批视频免费30分钟成人| 少妇熟女高潮流白浆| 日本少妇肉体裸交xxx| 欧美日本特级婬片视频| 精品综合久久久久久98| 国产精品你懂的在线播放| 伊人无码精品久久一区二区| 久久精品无码一区二区www| 国产亚洲视频中文字幕97精品| 曰本丰满熟妇xxxx性| 亚洲熟妇av一区二区三区浪潮| 亚洲日韩中文字幕久热| 777天堂麻豆爱综合视频| 女人高潮流白浆视频| 精品成人免费国产片| 成人亚洲欧美激情在线电影 | 国产97在线 | 中文| 欧洲亚洲1卡二卡三卡2021| 日本xxxx少妇高清hd| 国产精品无码一区二区三区电影| 成人爱做日本视频免费| 日日大香人伊一本线久| 久久综合九色综合久99| 熟妇人妻无码xxx视频 | 肉感饱满中年熟妇日本| 在线亚洲中文精品第1页|