在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Peptidyl-prolyl cis-trans isomerase E (PPIE)

  • 中文名稱:
    人PPIE重組蛋白
  • 貨號:
    CSB-YP890944HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PPIE重組蛋白
  • 貨號:
    CSB-EP890944HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PPIE重組蛋白
  • 貨號:
    CSB-EP890944HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PPIE重組蛋白
  • 貨號:
    CSB-BP890944HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PPIE重組蛋白
  • 貨號:
    CSB-MP890944HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PPIE
  • Uniprot No.:
  • 別名:
    Ab1-210; Cyclophilin 33; Cyclophilin E; Cyclophilin-33; CYP 33; CYP33; EC 5.2.1.8; Peptidyl prolyl cis trans isomerase E; Peptidyl-prolyl cis-trans isomerase E; Peptidylprolyl isomerase E (cyclophilin E); Peptidylprolyl isomerase E; PPIase E; PPIE; PPIE_HUMAN; Rotamase E
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-301
  • 氨基酸序列
    MATTKRVLYV GGLAEEVDDK VLHAAFIPFG DITDIQIPLD YETEKHRGFA FVEFELAEDA AAAIDNMNES ELFGRTIRVN LAKPMRIKEG SSRPVWSDDD WLKKFSGKTL EENKEEEGSE PPKAETQEGE PIAKKARSNP QVYMDIKIGN KPAGRIQMLL RSDVVPMTAE NFRCLCTHEK GFGFKGSSFH RIIPQFMCQG GDFTNHNGTG GKSIYGKKFD DENFILKHTG PGLLSMANSG PNTNGSQFFL TCDKTDWLDG KHVVFGEVTE GLDVLRQIEA QGSKDGKPKQ KVIIADCGEY V
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity.
  • 基因功能參考文獻:
    1. CypE is a host restriction factor that inhibits the functions of nucleoprotein, as well as viral replication and transcription, by impairing the formation of the viral ribonucleoprotein complex. PMID: 21887220
    2. binding of H3K4me3 to PHD3 domain of MLL and binding of the CYP33 RRM domain to PHD3 are mutually inhibitory, implying that PHD3 is a molecular switch for the transition between activation and repression of target genes PMID: 20677832
    3. PPIase domain of CyP33 regulates the conformation of MLL1 through proline isomerization within the PHD3-Bromo linker, thereby disrupting the PHD3-Bromo interface and facilitating binding of the MLL1-PHD3 domain to the CyP33-RRM domain. PMID: 20541251
    4. Data provide insight into the multiple functions of Cyp33 RRM and suggest a Cyp33-dependent mechanism for regulating the transcriptional activity of MLL. PMID: 20460131
    5. The results show that hCyP33 binds specifically to mRNA, namely poly(A)(+)RNA, and that binding stimulates the PPIase activity of hCyP33. PMID: 18258190

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Cyclophilin-type PPIase family, PPIase E subfamily
  • 組織特異性:
    Found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 數據庫鏈接:

    HGNC: 9258

    OMIM: 602435

    KEGG: hsa:10450

    UniGene: Hs.524690



主站蜘蛛池模板: 午夜亚洲www湿好大| 乱人伦人妻中文字幕无码久久网| 国产精品免费一区二区三区四区| 久章草在线精品视频免费观看| 午夜爱爱免费视频体验区| 噜噜高清欧美内射短视频| 日本熟妇浓毛| 狠狠色综合网站久久久久久久| 国产又色又爽又黄好看的视频| 国产经典三级av在线播放| 伊人久久精品无码二区麻豆| 在办公室被c到呻吟的动态图| 国产精品96久久久久久| 久久精品国产99久久香蕉| 国产美女视频免费观看网址| 人妻少妇精品一区二区三区 | 免费无码鲁丝片一区二区| 久久综合丝袜日本网| 丝袜老师高潮呻吟高潮| 国产乱码二卡3卡四卡| 国产92成人精品视频免费| 另类老妇奶性生bbwbbw| 国产成人8x人在线视频软件 | 国产α片免费观看在线人 | 久久精品国产免费播| 日产精品一区二区| _97夜夜澡人人爽人人喊_欧美| 天堂在/线资源中文在线8| 精品国产三级a∨在线欧美| 欧美xxxx黑人又粗又长精品| 日日av色欲香天天综合网| 免费无码成人av在线播放不卡| 国产又色又爽又黄又免费| 又紧又大又爽精品一区二区| 小12萝裸体视频国产| 亚洲第一a在线观看网站| 成人无码av片在线观看| 久久国产乱子伦精品免费午夜| 精品国产肉丝袜久久| 777天堂麻豆爱综合视频| 99久久精品免费看国产一区二区三区 |