在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human G-protein coupled receptor-associated sorting protein 1 (GPRASP1), partial

Recombinant Human G-protein coupled receptor-associated sorting protein 1 (GPRASP1), partial

  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-YP683365HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-EP683365HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-EP683365HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-BP683365HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-MP683365HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GPRASP1
  • Uniprot No.：
  • 別名：
    G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1; GASP1_HUMAN; Gprasp1; KIAA0443
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.
  • 基因功能參考文獻：
    1. Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1 PMID: 25706089
    2. Data suggest that specific serine/threonine residues in DRD2 (dopamine receptor D2) are involved in regulation of DRD2 endocytosis by GRK2 (G-protein coupled receptor kinase 2) and GASP1. PMID: 23082996
    3. GASP1 was identified as a potential new serum and biomarker for brain, pancreatic, lung, and breast cancers, and gliomas. PMID: 22483848
    4. LIR was able to induce gains in 1RM and quadriceps CSA similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN and increase in FLST isoforms, GASP-1, and SMAD-7 mRNA gene expression. PMID: 21900845
    5. These studies identify GASP-1 as a potential new serum and tumor biomarker for breast cancer. PMID: 21791203
    6. following this endocytosis the D(3) dopamine receptors fail to recycle and are instead targeted for degradation through an interaction with the G protein-coupled receptor (GPCR)-associated sorting protein-1 (GASP-1) PMID: 21030592
    7. This review describes the discovery of GASPs, their major features, interacting partners, functions and possible involvement in pathological situations including neurodegenerative diseases and cancer. PMID: 20394773
    8. identified a protein that binds preferentially to the cytoplasmic tail of the delta opioid receptor as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor-associated sorting protein (GASP) [GASP] PMID: 12142540
    9. Modulation of the D2-GASP interaction is important for the functional down-regulation of D2 dopamine receptors. PMID: 16049099

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    GPRASP family
  • 組織特異性：
    Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.
  • 數據庫鏈接：

    HGNC: 24834

    OMIM: 300417

    KEGG: hsa:9737

    STRING: 9606.ENSP00000355146

    UniGene: Hs.729265



主站蜘蛛池模板： 亚色九九九全国免费视频| 日韩精品毛片无码一区到三区| 久久成人影院精品777| 日韩人妻中文无码一区二区七区| 成 人 黄 色 大片| 欧美人妻久久精品| 精产一二三产区m553| 国产另类ts人妖一区二区| 国产成人亚洲综合无码18禁h| 亚洲youwu永久无码精品| 真实国产乱子伦对白在线播放| 4444亚洲人成无码网在线观看 | 午夜亚洲国产理论片中文| 香蕉久久精品日日躁夜夜躁夏| 99久久人妻无码精品系列| 国产成人综合久久三区| 国产精品一国产精品一k频道| 别揉我奶头~嗯~啊~一区二区三区 免费不卡无码av在线观看 | 女同免费毛片在线播放| 国产吃奶在线观看| 国产亚洲精品久久久久久牛牛| 国产亲子乱弄免费视频| 无码中文人妻在线三区| 一个人看免费视频www| 2022国产日产欧产精品| 午夜视频在线瓜伦| 亚洲日韩激情无码一区| 九九线精品视频在线观看| 精品av综合导航| 午夜片无码区私人影院| 国产成人无码免费视频在线| 国产av毛片亚洲含羞草社| 亚洲精品国产一区黑色丝袜| 亚洲国产成人精品无码区99| 亚洲美女高清无水av| 大尺度无遮挡激烈床震网站| 人人妻人人玩人人澡人人爽| 国产内射999视频一区| 免费无码午夜福利片69| 国产鲁鲁视频在线观看| 中文字幕无码不卡一区二区三区|