在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GPRASP1 Antibody

  • 中文名稱:
    GPRASP1兔多克隆抗體
  • 貨號:
    CSB-PA080057
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GPRASP1
  • 別名:
    G-protein coupled receptor-associated sorting protein 1 antibody; GASP antibody; GASP-1 antibody; GASP1 antibody; GASP1_HUMAN antibody; Gprasp1 antibody; KIAA0443 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GASP-1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.
  • 基因功能參考文獻:
    1. Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1 PMID: 25706089
    2. Data suggest that specific serine/threonine residues in DRD2 (dopamine receptor D2) are involved in regulation of DRD2 endocytosis by GRK2 (G-protein coupled receptor kinase 2) and GASP1. PMID: 23082996
    3. GASP1 was identified as a potential new serum and biomarker for brain, pancreatic, lung, and breast cancers, and gliomas. PMID: 22483848
    4. LIR was able to induce gains in 1RM and quadriceps CSA similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN and increase in FLST isoforms, GASP-1, and SMAD-7 mRNA gene expression. PMID: 21900845
    5. These studies identify GASP-1 as a potential new serum and tumor biomarker for breast cancer. PMID: 21791203
    6. following this endocytosis the D(3) dopamine receptors fail to recycle and are instead targeted for degradation through an interaction with the G protein-coupled receptor (GPCR)-associated sorting protein-1 (GASP-1) PMID: 21030592
    7. This review describes the discovery of GASPs, their major features, interacting partners, functions and possible involvement in pathological situations including neurodegenerative diseases and cancer. PMID: 20394773
    8. identified a protein that binds preferentially to the cytoplasmic tail of the delta opioid receptor as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor-associated sorting protein (GASP) [GASP] PMID: 12142540
    9. Modulation of the D2-GASP interaction is important for the functional down-regulation of D2 dopamine receptors. PMID: 16049099

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    GPRASP family
  • 組織特異性:
    Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.
  • 數據庫鏈接:

    HGNC: 24834

    OMIM: 300417

    KEGG: hsa:9737

    STRING: 9606.ENSP00000355146

    UniGene: Hs.729265



主站蜘蛛池模板: 西西人体www44rt大胆高清| 中国6一12呦女精品| 极品白嫩的小少妇| 国产超碰人人爽人人做| 久久er热在这里只有精品66| 亚洲无线看天堂av| 人人人插人人费| 欧美精品一产区二产区| 特级aaaaaaaaa毛片免费视频| 瑜伽裤国产一区二区三区| 中国国产野外1级毛片视频| 2021国产精品香蕉在线观看| 夜夜爱夜鲁夜鲁很鲁| 久久国产中文娱乐网| 国产一区二区三区成人欧美日韩在线观看| 国产精品无码综合区| 亚洲色偷偷偷网站色偷一区| 四虎成人精品一区二区免费网站| 黄a大片av永久免费| 快好爽射给我视频| 欧美级特黄aaaaaa片| 东京热大乱系列无码| 无码一区二区三区在线| 伊人激情av一区二区三区| 久久久亚洲欧洲日产国码αv| 久久99av无色码人妻蜜| 人妻av综合天堂一区| 国产黄a三级三级三级av在线看| 性色a∨精品高清在线观看| 国内一区二区三区香蕉aⅴ| 国产作爱激烈叫床视频| 老鲁夜夜老鲁| 97国产精品人妻无码久久久| 色欲来吧来吧天天综合网| 日本免费一区二区三区| 天天躁日日躁狠狠躁欧美老妇小说| 天堂网在线最新版www中文网| 欧美综合乱图图区乱图图区| 亚洲乱码伦小说区| 精品无码午夜福利理论片| 久久青青草原国产毛片|