在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human G-protein coupled receptor-associated sorting protein 1 (GPRASP1), partial

Recombinant Human G-protein coupled receptor-associated sorting protein 1 (GPRASP1), partial

  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-YP683365HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-EP683365HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-EP683365HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-BP683365HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GPRASP1重組蛋白
  • 貨號：
    CSB-MP683365HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GPRASP1
  • Uniprot No.：
  • 別名：
    G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1; GASP1_HUMAN; Gprasp1; KIAA0443
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.
  • 基因功能參考文獻：
    1. Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1 PMID: 25706089
    2. Data suggest that specific serine/threonine residues in DRD2 (dopamine receptor D2) are involved in regulation of DRD2 endocytosis by GRK2 (G-protein coupled receptor kinase 2) and GASP1. PMID: 23082996
    3. GASP1 was identified as a potential new serum and biomarker for brain, pancreatic, lung, and breast cancers, and gliomas. PMID: 22483848
    4. LIR was able to induce gains in 1RM and quadriceps CSA similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN and increase in FLST isoforms, GASP-1, and SMAD-7 mRNA gene expression. PMID: 21900845
    5. These studies identify GASP-1 as a potential new serum and tumor biomarker for breast cancer. PMID: 21791203
    6. following this endocytosis the D(3) dopamine receptors fail to recycle and are instead targeted for degradation through an interaction with the G protein-coupled receptor (GPCR)-associated sorting protein-1 (GASP-1) PMID: 21030592
    7. This review describes the discovery of GASPs, their major features, interacting partners, functions and possible involvement in pathological situations including neurodegenerative diseases and cancer. PMID: 20394773
    8. identified a protein that binds preferentially to the cytoplasmic tail of the delta opioid receptor as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor-associated sorting protein (GASP) [GASP] PMID: 12142540
    9. Modulation of the D2-GASP interaction is important for the functional down-regulation of D2 dopamine receptors. PMID: 16049099

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    GPRASP family
  • 組織特異性：
    Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.
  • 數據庫鏈接：

    HGNC: 24834

    OMIM: 300417

    KEGG: hsa:9737

    STRING: 9606.ENSP00000355146

    UniGene: Hs.729265



主站蜘蛛池模板： 中文字幕人妻被公上司喝醉在线| 久久久久久亚洲精品不卡| 久久国语露脸国产精品电影| 岛国片人妻三上悠亚| 亚洲欧洲日产韩国在线看片| 国产一区视频一区欧美| 国产精品久久久| 苍井空亚洲精品aa片在线播放| 成人精品动漫一区二区| 国产v在线最新观看视频| 麻豆传传媒久久久爱| 新婚少妇无套内谢国语播放| av色国产色拍| 国产亚洲精品综合一区| 亚洲国产精品成人久久| 久久精品人人槡人妻人| 欧美变态另类牲交| 中国白嫩丰满人妻videos| 少妇饥渴xxhd麻豆xxhd骆驼| 中文字幕日韩精品亚洲一区| 四虎国产精品永久地址49| 美女内射毛片在线看3d| 国产激情无码一区二区三区| 美女扒开奶罩露出奶头视频网站| 欧洲美女黑人粗性暴交| 女被男啪到哭的视频网站| 拍国产乱人伦偷精品视频| 综合欧美日韩国产成人| 人人爽天天碰天天躁夜夜躁| 国产婷婷一区二区三区| 亚洲色成人四虎在线观看| 夫妻免费无码v看片| 欧美老熟妇乱大交xxxxx| 天堂а√在线最新版中文| 国产作爱视频免费播放| 99久久精品无码一区二区三区| 国产免费麻传媒精品国产av| 在线不卡av片免费观看| 国产suv精品一区二区62| 日本无遮挡真人祼交视频| 人人爽人人爽人人片a免费|