在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GNAL Antibody, Biotin conjugated

  • 中文名稱:
    GNAL兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA009592LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GNAL Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Adenylate cyclase stimulating G alpha protein; olfactory type antibody; Adenylate cyclase-stimulating G alpha protein antibody; DYT25 antibody; G alpha olf antibody; Gnal antibody; GNAL_HUMAN antibody; Guanine nucleotide binding protein (G protein); alpha activating activity polypeptide; olfactory type antibody; Guanine nucleotide binding protein (G protein); alpha stimulating activity polypeptide; olfactory type antibody; Guanine nucleotide binding protein G(olf) subunit alpha antibody; Guanine nucleotide-binding protein G(olf) subunit alpha antibody; olfactory type antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Guanine nucleotide-binding protein G(olf) subunit alpha protein (4-116AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
  • 基因功能參考文獻:
    1. GNAL mutation may represent one of the rare causative genetic factors of isolated laryngeal dystonia. PMID: 27093447
    2. GNAL mutations are not a common cause of dystonia in the Brazilian population PMID: 26810727
    3. We report a novel GNAL mutation in Italian family with adult-onset, dominantly-inherited dystonia PMID: 26725140
    4. Mutations in the GNAL gene may not be a common cause of isolated dystonia in the Chinese population. PMID: 26365774
    5. This study demonstrated that Mutations in GNAL may cause Dystonia. PMID: 25847575
    6. identified two novel GNAL mutations: one heterozygous missense variant in GNAL exon 4, c.289A>G. PMID: 25382112
    7. The findings of this study further support GNAL as causative gene in adult-onset isolated dystonia. PMID: 24408567
    8. This study identified a novel likely disease-causing GNAL mutation in a Serbian patient with cervical dystonia and a classical DYT25 phenotype. PMID: 24729450
    9. Primary dystonia in the Amish-Mennonites is genetically diverse and includes not only the THAP1 indel founder mutation but also different mutations in THAP1 and GNAL as well as the TOR1A GAG deletion. PMID: 24500857
    10. GNAL variants seem to be a rare cause of primary torsion dystonia in our mainly sporadic German sample. PMID: 24151159
    11. Our own data suggest that GNAL mutations do not represent a common cause of dystonia in the U.K. population. PMID: 24222099
    12. The GNAL dystonia gene is central for striatal responses to dopamine (DA) and is a component of a molecular pathway already implicated in DOPA-responsive dystonia (DRD). PMID: 24144882
    13. GNAL mutations potentially increase ethnic susceptibility to movement disorders induced by dopamine antagonists. PMID: 24535567
    14. Mutations in GNAL gene can cause adult-onset primary dystonia in Chinese patients PMID: 23759320
    15. Familial adult-onset primary dystonia can result from mutations in GNAL. PMID: 23449625
    16. Mutations in GNAL cause primary torsion dystonia. PMID: 23222958
    17. these findings provide important clues to understanding physiological functions of XLGalpha(olf). PMID: 22120635
    18. investigation of whether polymorphisms in the alpha subunit of the Golf gene (A-->G in intron 3, and T-->G in intron 10) are associated with major depression; additionally tested for a parent-of-origin effect in separated gender groups PMID: 11901355
    19. promotes cellular invasion, survival and neuroendocrine differentiation in colon, kidney and prostate epithelial cells PMID: 12037684
    20. No support for the hypothesis that the olfactory G-protein gene is a major susceptibility factor for bipolar disorders. PMID: 12782961
    21. identified a transcriptional variant of the GNAL gene in chromosome 18p11.2 in susceptibility to bipolar disorder and schizophrenia PMID: 16044173
    22. Galpha(olf) variant XLGalpha(olf) interacts with the human adenosine A2A receptor PMID: 16818375
    23. We hypothesized that the G(s)-like subunit Galpha(olf), expressed in D1-rich areas of the brain, contributes to the genetic susceptibility of ADHD. We examined the inheritance pattern of 12 GNAL polymorphisms in 258 nuclear families. PMID: 17166517
    24. This study provides important clues toward understanding physiological functions of XLGalpha(olf). PMID: 19245791

    顯示更多

    收起更多

  • 相關疾病:
    Dystonia 25 (DYT25)
  • 蛋白家族:
    G-alpha family, G(s) subfamily
  • 組織特異性:
    Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
  • 數據庫鏈接:

    HGNC: 4388

    OMIM: 139312

    KEGG: hsa:2774

    STRING: 9606.ENSP00000334051

    UniGene: Hs.136295



主站蜘蛛池模板: 日本va欧美va欧美va精品| 中文字幕在线观看亚洲日韩| 亚洲成熟女人毛毛耸耸多| 亚洲综合激情另类小说区 | 波多野结衣初尝黑人| 亚洲精品少妇30p| 国产69精品久久久久久久| 国产欧美va欧美va香蕉在线观看 | 偷窥国产亚洲免费视频| 中文字幕日产乱码国内自| 人妻激情文学| 欧美成人免费一区二区| 久久er99热精品一区二区| 正在播放国产真实哭都没用| 无码国模大尺度视频在线观看| 亚洲中国精品精华液| 欧美浓毛大泬视频| 国产精品天干天干综合网| 亚洲色自偷自拍另类小说| 夜夜添无码试看一区二区三区| 亚洲午夜福利精品无码不卡| 精品少妇一区二区三区免费观| 午夜无码片在线观看影院| 欧美成人h亚洲综合在线观看| 日本成熟少妇喷浆视频| 亚洲国产美女精品久久久久| 国产乱人伦av麻豆网| 装睡被陌生人摸出水好爽| 久久综合精品无码av一区二区三区 | 日本va在线视频播放| 无码专区人妻系列日韩精品少妇| 99久久国语露脸精品国产 | 亚洲人成未满十八禁网站| 99国产精品久久久久久久日本竹| 久久天天躁夜夜躁狠狠躁2022| 人妻系列av无码专区| 国产精品天干在线观看| 国产裸体美女永久免费无遮挡| 国产熟睡乱子伦午夜视频| 亚洲日产av中文字幕无码偷拍| 人人妻人人澡人人爽偷拍台湾|