在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GNAL Antibody, FITC conjugated

  • 中文名稱:
    GNAL兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA009592LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GNAL Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Adenylate cyclase stimulating G alpha protein; olfactory type antibody; Adenylate cyclase-stimulating G alpha protein antibody; DYT25 antibody; G alpha olf antibody; Gnal antibody; GNAL_HUMAN antibody; Guanine nucleotide binding protein (G protein); alpha activating activity polypeptide; olfactory type antibody; Guanine nucleotide binding protein (G protein); alpha stimulating activity polypeptide; olfactory type antibody; Guanine nucleotide binding protein G(olf) subunit alpha antibody; Guanine nucleotide-binding protein G(olf) subunit alpha antibody; olfactory type antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Guanine nucleotide-binding protein G(olf) subunit alpha protein (4-116AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
  • 基因功能參考文獻:
    1. GNAL mutation may represent one of the rare causative genetic factors of isolated laryngeal dystonia. PMID: 27093447
    2. GNAL mutations are not a common cause of dystonia in the Brazilian population PMID: 26810727
    3. We report a novel GNAL mutation in Italian family with adult-onset, dominantly-inherited dystonia PMID: 26725140
    4. Mutations in the GNAL gene may not be a common cause of isolated dystonia in the Chinese population. PMID: 26365774
    5. This study demonstrated that Mutations in GNAL may cause Dystonia. PMID: 25847575
    6. identified two novel GNAL mutations: one heterozygous missense variant in GNAL exon 4, c.289A>G. PMID: 25382112
    7. The findings of this study further support GNAL as causative gene in adult-onset isolated dystonia. PMID: 24408567
    8. This study identified a novel likely disease-causing GNAL mutation in a Serbian patient with cervical dystonia and a classical DYT25 phenotype. PMID: 24729450
    9. Primary dystonia in the Amish-Mennonites is genetically diverse and includes not only the THAP1 indel founder mutation but also different mutations in THAP1 and GNAL as well as the TOR1A GAG deletion. PMID: 24500857
    10. GNAL variants seem to be a rare cause of primary torsion dystonia in our mainly sporadic German sample. PMID: 24151159
    11. Our own data suggest that GNAL mutations do not represent a common cause of dystonia in the U.K. population. PMID: 24222099
    12. The GNAL dystonia gene is central for striatal responses to dopamine (DA) and is a component of a molecular pathway already implicated in DOPA-responsive dystonia (DRD). PMID: 24144882
    13. GNAL mutations potentially increase ethnic susceptibility to movement disorders induced by dopamine antagonists. PMID: 24535567
    14. Mutations in GNAL gene can cause adult-onset primary dystonia in Chinese patients PMID: 23759320
    15. Familial adult-onset primary dystonia can result from mutations in GNAL. PMID: 23449625
    16. Mutations in GNAL cause primary torsion dystonia. PMID: 23222958
    17. these findings provide important clues to understanding physiological functions of XLGalpha(olf). PMID: 22120635
    18. investigation of whether polymorphisms in the alpha subunit of the Golf gene (A-->G in intron 3, and T-->G in intron 10) are associated with major depression; additionally tested for a parent-of-origin effect in separated gender groups PMID: 11901355
    19. promotes cellular invasion, survival and neuroendocrine differentiation in colon, kidney and prostate epithelial cells PMID: 12037684
    20. No support for the hypothesis that the olfactory G-protein gene is a major susceptibility factor for bipolar disorders. PMID: 12782961
    21. identified a transcriptional variant of the GNAL gene in chromosome 18p11.2 in susceptibility to bipolar disorder and schizophrenia PMID: 16044173
    22. Galpha(olf) variant XLGalpha(olf) interacts with the human adenosine A2A receptor PMID: 16818375
    23. We hypothesized that the G(s)-like subunit Galpha(olf), expressed in D1-rich areas of the brain, contributes to the genetic susceptibility of ADHD. We examined the inheritance pattern of 12 GNAL polymorphisms in 258 nuclear families. PMID: 17166517
    24. This study provides important clues toward understanding physiological functions of XLGalpha(olf). PMID: 19245791

    顯示更多

    收起更多

  • 相關疾病:
    Dystonia 25 (DYT25)
  • 蛋白家族:
    G-alpha family, G(s) subfamily
  • 組織特異性:
    Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
  • 數據庫鏈接:

    HGNC: 4388

    OMIM: 139312

    KEGG: hsa:2774

    STRING: 9606.ENSP00000334051

    UniGene: Hs.136295



主站蜘蛛池模板: 久热这里只有精品99在线观看| 成人伊人青草久久综合网| 欧美精品18videos性欧美| 一卡二卡3卡四卡网站精品| 免费特级黄毛片| 久久人人爽人人爽人人片亞洲| 老妇高潮潮喷到猛进猛出| 青草精品国产福利在线视频| 无码人妻丝袜视频在线播免费 | 黑人大战欲求不满人妻| 性饥渴的农村熟妇| 久久中文字幕人妻熟av女蜜柚m| 久久99国产精一区二区三区| 激情射精爆插热吻无码视频| 国产精品自在线拍亚洲另类| 人妻无码精品久久亚瑟影视| 国外亚洲成av人片在线观看| 美女裸体视频永久免费| 亚洲精品国产熟女久久久| 国产99青草视频在线播放视 | 国产成人av在线影院| 国产后进白嫩翘臀在线播放| 在线v片免费观看视频| 国产69精品久久久久乱码韩国| 国产精品久久久久久av| 天天噜日日噜狠狠噜免费| 亚洲国产综合av在线观看| 婷婷激情综合色五月久久竹菊影视 | 亚洲国产老鸭窝一区二区三区| 久久久久亚洲精品| 亚洲欧美日韩综合一区| 亚洲欧美成人a∨观看| 色又黄又爽18禁免费网站| 最近中文av字幕在线中文 | 国产性猛交╳xxx乱大交| 欧美肥老太牲交| 国产高清在线精品二区| 国产精品成人va在线观看| 国产免费mv大全视频网站| h人成在线看免费视频| 国产三级精品三级|