在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 跨膜蛋白
  4. Recombinant Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hcn3)

Recombinant Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hcn3)

  • 中文名稱：
    小鼠Hcn3重組蛋白
  • 貨號：
    CSB-CF010218MO
  • 說明書：
  • 規格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產品詳情

  • 基因名：
    Hcn3
  • Uniprot No.：
  • 別名：
    Hcn3; Hac3; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3; Hyperpolarization-activated cation channel 3; HAC-3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-779
  • 氨基酸序列
    MEEEARPAAGAGEAATPARETPPAAPAQARAASGGVPESAPEPKRRQLGTLLQPTVNKFS LRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEE NSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSI PVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHA LFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQ EKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRG LVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGAR DTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAM DRLRRIGKKNSILQRKRSEPSPGSSGGVMEQHLVQHDRDMARGVRGLAPGTGARLSGKPV LWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVR AGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGARRLGPRGRPLSAS QPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPPRSSVPEPVTPRGPQISANM
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.
  • 基因功能參考文獻：
    1. KCTD3 is an accessory subunit of native HCN3 complexes PMID: 23382386
    2. HCN3 contributes to the ventricular action potential waveform in the murine heart. PMID: 21903939
    3. functional expression of HCN3 channels in thalamic intergeniculate leaflet neurons is crucial for intrinsic excitability and rhythmic burst firing PMID: 21753018
    4. Although HCN channel function was greatly reduced in MitoPark DA neurons, mRNA levels for the isoforms most prominently expressed in DA-rich midbrain areas (HCN-3 and HCN-1) were similar to those of the control mice. PMID: 21233488
    5. the precise contribution of HCN4 to sinus node function still is unresolved, and in particular the role of HCN4 in human autonomic heart rate response has yet to be established. PMID: 20693575
    6. the distinct expression pattern in conjunction with the unusual biophysical properties implies that HCN3 may play an unique role in the body PMID: 15923185
    7. These data establish HCN3 up-regulation as a novel candidate mechanism that might contribute to the in vivo changes of electrical activity in basal ganglia output neurons of the parkinsonian brain. PMID: 19320057

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel HCN family
  • 組織特異性：
    Detected in hypothalamus, amygdala, olfactory bulb, hippocampus and retina (at protein level). Highly expressed in brain and heart, in particular in ventricle, atrium and in sinoatrial node (SAN). Detected at low levels in skeletal muscle and lung.
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美老妇与zozoz0交| 男女一边摸一边做爽爽的免费阅读| 国产初高中生真实在线视频| 亚洲成a∨人片在线观看不卡 | 无码人妻人妻经典| 国产乱子伦视频一区二区三区| 亚洲和欧洲一码二码区别7777| 一区一区三区产品乱码亚洲| 性欧美老妇另类xxxx| 99精品无人区乱码1区2区3区 | 日韩人妻少妇一区二区| 无码一区二区三区在线| 精品无码中文视频在线观看| 午夜男女无遮挡拍拍视频| 玩弄丰满熟妇xxxxx性60| 中文无码日韩欧av影视| 秋霞特色aa大片| 国产精品不卡无码av在线播放 | 51久久国产露脸精品国产| 亚洲精品成人片在线观看精品字幕| 国内外精品激情刺激在线| 永久免费观看美女裸体视频的网站| 人人妻人人澡人人爽人人精品电影| 国产suv精品一区二区6| 国产偷窥盗摄一区二区| 日本大香伊一区二区三区| 国产精品99久久免费黑人人妻| 性色欲情网站| 久久天天躁狠狠躁夜夜躁app| 四虎永久在线精品免费网站| 韩国精品福利一区二区三区| 免费人成在线观看视频无码| 日本xxxx18野外无毒不卡| 色狠狠成人综合网| 色综合色欲色综合色综合色综合r 四虎亚洲欧美成人网站 | 久久人妻国产精品| 欧美真人性做爰一二区| 日本不卡高字幕在线2019| 久久99青青精品免费观看| 国产乱码二卡3卡四卡| 亚洲精品456在线播放|