在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Polypeptide N-acetylgalactosaminyltransferase 3 (Galnt3)-VLPs

  • 中文名稱:
    Recombinant Mouse Polypeptide N-acetylgalactosaminyltransferase 3 (Galnt3)-VLPs
  • 貨號:
    CSB-MP009210MO
  • 說明書:
  • 規格:
  • 其他:

產品詳情

  • 基因名:
    Galnt3
  • Uniprot No.:
  • 別名:
    Polypeptide GalNAc transferase 3;GalNAc-T3;pp-GaNTase 3;Protein-UDP acetylgalactosaminyltransferase 3;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    Mammalian cell
  • 表達區域:
    1-633aa
  • 氨基酸序列
    MAHLKRLVKLHIKRHYHRKFWKLGAVIFFFLVVLILMQREVSVQYSKEESKMERNLKNKNKMLDFMLEAVNNIKDAMPKMQIGAPIKENIDVRERPCLQGYYTAAELKPVFDRPPQDSNAPGASGKPFKITHLSPEEQKEKERGETKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDDYLHEKLEEYIKQFSIVKIVRQQERKGLITARLLGAAVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSISKKYFEHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHVFRSKSPHTFPKGTQVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKSFGDLSKRFEIKKRLQCKNFTWYLNTIYPEAYVPDLNPVISGYIKSVGQPLCLDVGENNQGGKPLILYTCHGLGGNQYFEYSAQREIRHNIQKELCLHATQGVVQLKACVYKGHRTIAPGEQIWEIRKDQLLYNPLFKMCLSSNGEHPNLVPCDATDLLQKWIFSQND
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 10xHis-tagged
    If you have specified tag type, please tell us and we will check if it's possible to develop.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from PBS, 6% Trehalose, pH 7.4.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex. Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Glycosylates FGF23. Probably glycosylates fibronectin in vivo. May be involved in phosphate homeostasis.
  • 基因功能參考文獻:
    1. Overexpression of Galnt3 in chondrocytes causes dwarfism due to the increase of mucin-type O-glycans and a reduction in chondroitin sulfates. PMID: 25107907
    2. The stabilized Fgf23-Autosomal dominant hypophosphatemic rickets allele reversed the Galnt3-null phenotype and normalized total Fgf23, serum phosphorus, and bone Fgf23 mRNA. PMID: 25051439
    3. The deficiency of Galnt3 results in a severe reduction of mucin-type O-glycans in spermatids and causes impaired acrosome formation, leading to oligoasthenoteratozoospermia, and Galnt3 may also be involved in the process of fertilization. PMID: 23052838
    4. A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis. PMID: 22912827
    5. dietary phosphate restriction normalizes biochemical and skeletal phenotypes of Galnt3 knockout mice and, thus, can be an effective therapy for tumoral calcinosis. PMID: 22009723
    6. The expression levels of murine ppGalNAc-Ts (mGalNAc-Ts), T1, T2, T3, T4, T6, and T7 were compared between mouse colon carcinoma colon 38 cells and variant SL4 cells, selected for their metastatic potentials. PMID: 20077002
    7. Galnt3-deficient mice have a biochemical phenotype of tumoral calcinosis and provide in vivo evidence that Galnt3 plays an essential role in proper secretion of Fgf23 in mice. PMID: 19213845

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性:
    Highly expressed in the reproductive tract, principally in the testis and uterus, and to a lesser degree in the cervix with only trace levels in the ovary. Also expressed at high level in sublingual gland, stomach and colon, with more moderate amounts pre
  • 數據庫鏈接:


主站蜘蛛池模板: 中美日韩毛片免费播放| 青青草av一区二区三区| 女人被做到高潮免费视频| 国产激情久久久久影院小草| 国产成人最新三级在线视频| 四虎成人国产精品永久在线 | 久久国产乱子伦精品免费女人| 天堂网在线www中文| 午夜福利92国语| 亚洲午夜av久久久精品影院| 婷婷六月丁香缴 清| 成人片黄网站a毛片免费观看| 亚洲乱码中文字幕手机在线| 夜夜爽日日澡人人添| 永久免费看mv网站入口亚洲| 日韩 国产 变态另类 欧美| 波多野结av在线无码中文| 久久久久免费看黄a片app| 欧美日韩午夜群交多人轮换| 红杏亚洲影院一区二区三区| 亚洲高清专区日韩精品| 久久久橹橹橹久久久久| 天天摸日日摸狠狠添| 亚洲国产成人精品久久久| 中文字幕无码专区人妻系列| 亚洲乱码中文字幕综合234| 高潮喷水的毛片| 99国产欧美久久久精品蜜芽| 中文字幕日产熟女乱码| 熟妇人妻不卡中文字幕| 欧美大胆少妇bbw| 少妇伦子伦精品无码styles| 一边做一边喷17p亚洲乱妇50p| 欧美写真视频在线观看| 日本熟妇浓毛hdsex| 亚洲不乱码卡一卡二卡4卡5卡| 让少妇高潮无乱码高清在线观看| 特黄特色大片免费播放器图片| 日韩欧美成人免费观看| 亚洲龙腾成小说人网| 4hu亚洲人成人无码网www电影首页|