在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Polypeptide N-acetylgalactosaminyltransferase 3 (Galnt3)

In Stock
  • 中文名稱:
    小鼠Galnt3重組蛋白
  • 貨號:
    CSB-CF009210MO
  • 規格:
    ¥9720
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    Galnt3
  • Uniprot No.:
  • 別名:
    Polypeptide GalNAc transferase 3;GalNAc-T3;pp-GaNTase 3;Protein-UDP acetylgalactosaminyltransferase 3;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    in vitro E.coli expression system
  • 分子量:
    74.5 kDa
  • 表達區域:
    1-633aa
  • 氨基酸序列
    MAHLKRLVKLHIKRHYHRKFWKLGAVIFFFLVVLILMQREVSVQYSKEESKMERNLKNKNKMLDFMLEAVNNIKDAMPKMQIGAPIKENIDVRERPCLQGYYTAAELKPVFDRPPQDSNAPGASGKPFKITHLSPEEQKEKERGETKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDDYLHEKLEEYIKQFSIVKIVRQQERKGLITARLLGAAVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSISKKYFEHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHVFRSKSPHTFPKGTQVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKSFGDLSKRFEIKKRLQCKNFTWYLNTIYPEAYVPDLNPVISGYIKSVGQPLCLDVGENNQGGKPLILYTCHGLGGNQYFEYSAQREIRHNIQKELCLHATQGVVQLKACVYKGHRTIAPGEQIWEIRKDQLLYNPLFKMCLSSNGEHPNLVPCDATDLLQKWIFSQND
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Glycosylates FGF23. Probably glycosylates fibronectin in vivo. May be involved in phosphate homeostasis.
  • 基因功能參考文獻:
    1. Overexpression of Galnt3 in chondrocytes causes dwarfism due to the increase of mucin-type O-glycans and a reduction in chondroitin sulfates. PMID: 25107907
    2. The stabilized Fgf23-Autosomal dominant hypophosphatemic rickets allele reversed the Galnt3-null phenotype and normalized total Fgf23, serum phosphorus, and bone Fgf23 mRNA. PMID: 25051439
    3. The deficiency of Galnt3 results in a severe reduction of mucin-type O-glycans in spermatids and causes impaired acrosome formation, leading to oligoasthenoteratozoospermia, and Galnt3 may also be involved in the process of fertilization. PMID: 23052838
    4. A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis. PMID: 22912827
    5. dietary phosphate restriction normalizes biochemical and skeletal phenotypes of Galnt3 knockout mice and, thus, can be an effective therapy for tumoral calcinosis. PMID: 22009723
    6. The expression levels of murine ppGalNAc-Ts (mGalNAc-Ts), T1, T2, T3, T4, T6, and T7 were compared between mouse colon carcinoma colon 38 cells and variant SL4 cells, selected for their metastatic potentials. PMID: 20077002
    7. Galnt3-deficient mice have a biochemical phenotype of tumoral calcinosis and provide in vivo evidence that Galnt3 plays an essential role in proper secretion of Fgf23 in mice. PMID: 19213845

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性:
    Highly expressed in the reproductive tract, principally in the testis and uterus, and to a lesser degree in the cervix with only trace levels in the ovary. Also expressed at high level in sublingual gland, stomach and colon, with more moderate amounts pre
  • 數據庫鏈接:


主站蜘蛛池模板: 天堂官网在线资源网| 四虎国产成人永久精品免费| 无码少妇精品一区二区免费动态| 无码国产一区二区三区四区| 国产产在线精品亚洲aavv| 天天av天天翘天天综合网| 丰满岳跪趴高撅肥臀尤物在线观看| 激情射精爆插热吻无码视频 | 久久人人做人人爽人人av| 无尺码精品产品网站| 亚洲人成网站色7799| 免费人成视频在线| 国产精品亚洲综合久久系列| 亚洲热妇无码av在线播放| 亚洲成av人片在www色猫咪| 免费观看激色视频网站| 偷窥国产亚洲免费视频| 国产最大成人亚洲精品| 成人免费毛片aaaaaa片| 最新成年女人毛片免费基地| 中文字幕无码专区人妻系列| 欧美精品一国产成人综合久久 | 在线观看成人年视频免费| 亚洲欲色欲色xxxxx在线| 里番本子纯肉侵犯肉全彩无码| 国产免费丝袜调教视频| 偷窥村妇洗澡毛毛多| 亚洲人成人无码www影院 | 国产偷v国产偷v亚洲高清| 无码成人aaaaa毛片| 国产在线不卡视频免费视频| 国产精品久久国产精麻豆99网站| 欧美 日韩 国产 成人 在线观看| 人妻少妇heyzo无码专区| 日本熟妇hdsex视频| 国产综合色在线精品| 日韩超碰人人爽人人做人人添 | 精品国产乱码久久久久久1区2区| 免费国产h视频在线观看| 亚洲第一在线综合网站| 国产乱子影视频上线免费观看|