在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse CD82 antigen (Cd82)

  • 中文名稱:
    Recombinant Mouse CD82 antigen(Cd82)
  • 貨號:
    CSB-CF004961MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Cd82; Kai1CD82 antigen; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1 homolog; CD antigen CD82
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-266
  • 氨基酸序列
    MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKNSFISVLQTSSSSLQVGAYVFI GVGAITIVMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNT VMDIIRNYTANATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIK EEDNQLIVKKGFCEADNSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVI ELLGLFLSICLCRYIHSEDYSKVPKY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    10xHis-SUMO-tag
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
  • 基因功能參考文獻:
    1. The CD82 is a functional surface marker of long-term repopulating hematopoietic stem cells (LT-HSCs) that maintains quiescence through interaction with DARC-expressing macrophages in the bone marrow stem cell niche. PMID: 26996598
    2. Loss of Kai1 expression is associated with neoplasm metastasis. PMID: 23401136
    3. The synergistic effects of CD82 and GM3 or GM2/GM3 ganglioside on EGFR expression and phosphorylation and cMet activation are responsible for CD82 inhibition of EGF- and HGF-dependent cell motility and migration of Hepa1-6 cells. PMID: 23968914
    4. the CD82 tetraspanin is specifically recruited to pathogen-containing phagosomes prior to fusion with lysosomes. PMID: 21149584
    5. KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase PMID: 20089858
    6. Hypoxia-dependent induction of KAI1 was directly mediated by hypoxia-inducible factor-1alpha binding on the promoter, which subsequently caused increased recruitment of RNA polymerase II for transcriptional activation. PMID: 20123085
    7. An antibody to this protein that can specifically detect murine Kai1/CD82, should be useful in addressing the mechanism of action of Kai1 in metastatic suppression. PMID: 16372335
    8. gp78 promotes sarcoma metastasis by targeting KAI1 for degradation PMID: 18037895
    9. The transgenic adenocarcinoma of mouse prostate model encompasses androgen depletion independent sublines with increased tumorigenicity and invasiveness. All showed downregulation in tumor suppressor, E-cadherin, and metastatis suppressor, KAI-1. PMID: 18247402

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Tetraspanin (TM4SF) family
  • 組織特異性:
    Highest expression in the spleen and the kidney. Low expression in skeletal muscle and in the heart.
  • 數據庫鏈接:


主站蜘蛛池模板: 99精品众筹模特自拍视频| 中文字幕av无码人妻| 亚洲成av人在线观看天堂无码| 国产精品毛片av999999| 亚洲国产香蕉碰碰人人| 国产精品久久久久9999爆乳 | 国产尤物精品视频| 欧美色就是色| 免费无人区男男码卡二卡| 亚洲中文无码av永久伊人| 97se色综合一区二区二区 | 毛片无码一区二区三区a片视频| 免费人成年激情视频在线观看 | 欧美最新精品videossexohd| 丝袜美腿一区二区三区| 久久精品黄aa片一区二区三区 | 欧美日韩精品人妻狠狠躁免费视频| 18禁成年免费无码国产| 亚洲熟妇av午夜无码不卡| 国产精华av午夜在线观看| 中文字幕av无码一区二区三区电影| 亚洲老妇色熟女老太| 久久综合一色综合久久小蛇| 亚洲中文有码字幕青青| 亚洲欧洲日本综合aⅴ在线 | 欧美精品中文字幕在线视| 国产农村妇女毛片精品久久| 欧美一区二区三区久久综合| 成人免费无遮挡在线播放| 精品成人毛片一区二区| 国产真人性做爰久久网站| 日本理伦片午夜理伦片| 欧美亚洲色aⅴ大片| 精品国产一区二区三区免费| 日本55丰满熟妇厨房伦| 少妇高潮太爽了在线视| 亚洲国产人在线播放首页| 69sex久久精品国产麻豆| 婷婷久久香蕉五月综合| 午夜国产亚洲精品一区| 免费三级网站|