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Cd82 Antibody

  • 中文名稱:
    Cd82兔多克隆抗體
  • 貨號:
    CSB-PA004961LA01MO
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: Cd82 antibody at 2µg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: A549 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 30 kDa
      Observed band size: 30 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Mus musculus (Mouse) Cd82 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Cd82 antibody; Kai1CD82 antigen antibody; C33 antigen antibody; IA4 antibody; Inducible membrane protein R2 antibody; Metastasis suppressor Kangai-1 homolog antibody; CD antigen CD82 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Mouse, Human
  • 免疫原:
    Recombinant Mouse CD82 antigen protein (111-227AA)
  • 免疫原種屬:
    Mus musculus (Mouse)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,Cd82 Antibody (CSB-PA004961LA01MO),的標記方式是Non-conjugated。對于Cd82 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA004961LB01MO Cd82 Antibody, HRP conjugated ELISA
    FITC CSB-PA004961LC01MO Cd82 Antibody, FITC conjugated
    Biotin CSB-PA004961LD01MO Cd82 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
  • 基因功能參考文獻:
    1. The CD82 is a functional surface marker of long-term repopulating hematopoietic stem cells (LT-HSCs) that maintains quiescence through interaction with DARC-expressing macrophages in the bone marrow stem cell niche. PMID: 26996598
    2. Loss of Kai1 expression is associated with neoplasm metastasis. PMID: 23401136
    3. The synergistic effects of CD82 and GM3 or GM2/GM3 ganglioside on EGFR expression and phosphorylation and cMet activation are responsible for CD82 inhibition of EGF- and HGF-dependent cell motility and migration of Hepa1-6 cells. PMID: 23968914
    4. the CD82 tetraspanin is specifically recruited to pathogen-containing phagosomes prior to fusion with lysosomes. PMID: 21149584
    5. KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase PMID: 20089858
    6. Hypoxia-dependent induction of KAI1 was directly mediated by hypoxia-inducible factor-1alpha binding on the promoter, which subsequently caused increased recruitment of RNA polymerase II for transcriptional activation. PMID: 20123085
    7. An antibody to this protein that can specifically detect murine Kai1/CD82, should be useful in addressing the mechanism of action of Kai1 in metastatic suppression. PMID: 16372335
    8. gp78 promotes sarcoma metastasis by targeting KAI1 for degradation PMID: 18037895
    9. The transgenic adenocarcinoma of mouse prostate model encompasses androgen depletion independent sublines with increased tumorigenicity and invasiveness. All showed downregulation in tumor suppressor, E-cadherin, and metastatis suppressor, KAI-1. PMID: 18247402

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  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Tetraspanin (TM4SF) family
  • 組織特異性:
    Highest expression in the spleen and the kidney. Low expression in skeletal muscle and in the heart.
  • 數據庫鏈接:


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