在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Macaca fascicularis Mucolipin-1 (MCOLN1)

  • 中文名稱:
    獼猴MCOLN1重組蛋白
  • 貨號(hào):
    CSB-CF720219MOV
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    MCOLN1; QorA-13738; Mucolipin-1; Mucolipidin; Transient receptor potential channel mucolipin 1; TRPML1
  • 種屬:
    Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-580
  • 氨基酸序列
    MTDPAGPRGSETERLLTPNPGYGTQVGPSPAPPTPPEEEDLRRRLKYFFMSPCDKFRAKG RKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAY TQEQLYQAIFHAVDQYLALPDVSLGRYAYVHGGGDPWTNGSGLALCQRYYHRGHVDPAND TFDIDPMVVTDCIQVDPPERPPPSPSDDLALLEGSSSYKNLTLKFHKLVNVTIHFRLKTI NLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFRHGDNSFRLL FDVVVILTCSLSFLLCARSLLRGFLLQNEFVRFMWRQRRRVISLWERLEFVNGWYILLVT SDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRV ALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAM QAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAY IAQCQDSPTSGKFRRGSGSACSLLCCCGRDPSEEHSLLVN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Nonselective cation channel probably playing a role in the regulation of membrane trafficking events and of metal homeostasis. Proposed to play a major role in Ca(2+) release from late endosome and lysosome vesicles to the cytoplasm, which is important for many lysosome-dependent cellular events, including the fusion and trafficking of these organelles, exocytosis and autophagy. Required for efficient uptake of large particles in macrophages in which Ca(2+) release from the lysosomes triggers lysosomal exocytosis. May also play a role in phagosome-lysosome fusion. Involved in lactosylceramide trafficking indicative for a role in the regulation of late endocytic membrane fusion/fission events. By mediating lysosomal Ca(2+) release is involved in regulation of mTORC1 signaling and in mTOR/TFEB-dependent lysosomal adaptation to environmental cues such as nutrient levels. Seems to act as lysosomal active oxygen species (ROS) sensor involved in ROS-induced TFEB activation and autophagy. Functions as a Fe(2+) permeable channel in late endosomes and lysosomes. Proposed to play a role in zinc homeostasis probably implicating its association with TMEM163. In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells.; May contribute to cellular lipase activity within the late endosomal pathway or at the cell surface which may be involved in processes of membrane reshaping and vesiculation, especially the growth of tubular structures. However, it is not known, whether it conveys the enzymatic activity directly, or merely facilitates the activity of an associated phospholipase.
  • 亞細(xì)胞定位:
    Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cell projection, phagocytic cup. Cytoplasmic vesicle, phagosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Transient receptor (TC 1.A.4) family, Polycystin subfamily, MCOLN1 sub-subfamily
  • 數(shù)據(jù)庫鏈接:

    KEGG: mcf:102143748

    UniGene: Mfa.6343



主站蜘蛛池模板: 免费国精产品自偷自偷免费看| av天堂亚洲区无码先锋影音| 99精品众筹模特自拍视频| 国产一区二区不卡老阿姨| 欧美激情一区二区三区高清视频| 亚洲精品久久午夜无码一区二区| 青草av久久一区二区三区| 在线精品亚洲一区二区小说| 特级毛片a片久久久久久| 国产高清在线精品一区| 大肉大捧一进一出好爽动态图| 免费人成视频网站在线观看18| av无码久久久久不卡网站下载| 国产精品一区二区av在线观看| 免费又黄又爽1000禁片| 国产欧美在线一区二区三| 国产精品无码a∨麻豆| 东北老女人高潮大叫对白| 一卡二卡三卡视频| 成人亚洲欧美在线观看| 亚洲超碰无码色中文字幕97| 四虎av永久在线精品免费观看 | 射精区-区区三区| 午夜福利理论片在线观看播放| 毛色毛片免费观看| 精品国产乱码久久久久久下载| 人妻精品人妻无码一区二区三区| 巨胸不知火舞露双奶头无遮挡| 天天做天天大爽天天爱| 色噜噜亚洲男人的天堂www| 中国极品少妇videossexhd| 特黄特色的大片观看免费视频| 久久香蕉国产线看观看亚洲小说| 日日摸处处碰夜夜爽| 337p日本欧洲亚洲大胆裸体艺术| 手机在线看片| 51被公侵犯玩弄漂亮人妻 | 色一情一乱一乱一区99av| 精品人妻无码区二区三区| 韩产日产国产欧产| 全部露出来毛走秀福利视频|