在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human G-protein coupled receptor 161 (GPR161)

  • 中文名稱:
    人GPR161重組蛋白
  • 貨號:
    CSB-CF836681HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    GPR161; G-protein coupled receptor 161; G-protein coupled receptor RE2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-529
  • 氨基酸序列
    MSLNSSLSCRKELSNLTEEEGGEGGVIITQFIAIIVITIFVCLGNLVIVVTLYKKSYLLT LSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGV IAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVA AWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRK NSSTSTSSSGSRRNAFQGVVYSANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSS VSPSLETWATWLSFASAVCHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFS ISNRITDLGLSPHLTALMAGGQPLGHSSSTGDTGFSCSQDSGTDMMLLEDYTSDDNPPSH CTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLDSYAASLAKAIEAEAKINLFG EEALPGVLVTARTVPGGGFGGRRGSRTLVSQRLQLQSIEEGDVLAAEQR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    10xHis-SUMO-tag
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown.
  • 基因功能參考文獻:
    1. Gpr161 is a critical factor in the basal suppression machinery of Shh signaling, neural tube morphogenesis and closure. (Review) PMID: 27731925
    2. Gpr161 is an A-kinase anchoring protein and the cAMP-sensing Gpr161:PKA complex acts as cilium-compartmentalized signalosome PMID: 27357676
    3. Smoothened determines beta-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. PMID: 27002170
    4. G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion. PMID: 24599592
    5. False positive non-synonymous polymorphisms of G-protein coupled receptor genes. PMID: 11959142

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數據庫鏈接:

    HGNC: 23694

    OMIM: 612250

    KEGG: hsa:23432

    STRING: 9606.ENSP00000271357

    UniGene: Hs.271809



主站蜘蛛池模板: 污18禁污色黄网站免费| 久久成人国产精品| 天天躁日日躁很很很躁| 日本特黄特色特爽大片| 华人在线亚洲欧美精品| 无码a∨高潮抽搐流白浆| 久久久国产乱子伦精品作者| 人妻少妇69式99偷拍| 中文国产乱码在线人妻一区二区 | 精品国产午夜肉伦伦影院| 伦理片午夜视频在线观看| 亚洲欧美午夜理论电影在线观看| 久久久久久久久毛片精品| 国产麻豆成人传媒免费观看| 国产精品国产成人国产三级| 国内无遮挡18禁无码网站免费| 亚洲午夜av久久久精品影院色戒| 精品午夜福利无人区乱码一区| 国产一区二区在线视频| 无码熟熟妇丰满人妻啪啪 | 香草乱码一二三四区别| 久久久精品日本一区二区三区| 老司机午夜免费精品视频| 国产日产欧产精品精品ai| 国产好大好硬好爽免费视频| 大肉大捧一进一出好爽| 少妇又爽又刺激视频| 成人自慰女黄网站免费大全| 国产高清国产精品国产专区| 人妻无码久久精品人妻| 2017亚洲天堂最新地址| 国产360激情盗摄全集| 国产精品无码天天爽视频| 成人内射国产免费观看| 美乳丰满人妻无码视频| 四虎www永久在线精品| 窝窝午夜色视频国产精品破| 亚洲ⅴ国产v天堂a无码二区| 色欲来吧来吧天天综合网| 亚洲精品久久久狠狠爱小说| 亚洲精品av中文字幕在线|