在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPR161 Antibody, FITC conjugated

GPR161 Antibody, FITC conjugated

  • 中文名稱：
    GPR161兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA04114C0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GPR161 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GPR161 antibody; G-protein coupled receptor 161 antibody; G-protein coupled receptor RE2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown.
  • 基因功能參考文獻：
    1. Gpr161 is a critical factor in the basal suppression machinery of Shh signaling, neural tube morphogenesis and closure. (Review) PMID: 27731925
    2. Gpr161 is an A-kinase anchoring protein and the cAMP-sensing Gpr161:PKA complex acts as cilium-compartmentalized signalosome PMID: 27357676
    3. Smoothened determines beta-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. PMID: 27002170
    4. G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion. PMID: 24599592
    5. False positive non-synonymous polymorphisms of G-protein coupled receptor genes. PMID: 11959142

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：

    HGNC: 23694

    OMIM: 612250

    KEGG: hsa:23432

    STRING: 9606.ENSP00000271357

    UniGene: Hs.271809



主站蜘蛛池模板： 国产福利姬喷水福利在线观看| 精品黑人一区二区三区久久| 小泽玛利亚一区二区在线观看 | 动漫精品专区一区二区三区| 国产三级在线观看播放| 亚洲国产中文在线二区三区免| 无码一区二区三区中文字幕| 醉酒后少妇被疯狂内射视频| 人妻丰满熟妇av无码处处不卡| 中文日产幕无线码6区收藏| 人妻少妇熟女javhd| 亚洲熟妇av一区二区三区漫画| 无码人妻精品一区二区三区66| 伊人狠狠色丁香婷婷综合| 亚洲粉嫩高潮的18p| 亚洲精品国产自在久久| 99精品国产一区二区三区不卡| 爆乳喷奶水无码正在播放| 亚洲国产精品一区二区制服| 一本色道久久东京热| 亚洲日韩中文字幕在线不卡最新| 国产后入又长又硬| 精品国产黑色丝袜高跟鞋| 亚洲高清成人av电影网站 | 亚洲中文字幕无码av正片| 久久久免费无码成人影片| 中文字幕色av一区二区三区| 青春草在线视频免费观看 | 日本一上一下爱爱免费| 国产色无码精品视频免费| 激情综合五月| 无码人妻丰满熟妇精品区| 无码一区二区三区老色鬼| 亚洲欧洲美洲在线观看| 久久精品国产69国产精品亚洲| 亚洲最大av无码国产| 免费国产成人高清在线观看网站| 国产免费极品av吧在线观看| www国产精品内射老师| 国产色视频自在线观看| 国产亚洲视频在线观看网址|