在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPR161 Antibody, FITC conjugated

GPR161 Antibody, FITC conjugated

  • 中文名稱：
    GPR161兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA04114C0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GPR161 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GPR161 antibody; G-protein coupled receptor 161 antibody; G-protein coupled receptor RE2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown.
  • 基因功能參考文獻：
    1. Gpr161 is a critical factor in the basal suppression machinery of Shh signaling, neural tube morphogenesis and closure. (Review) PMID: 27731925
    2. Gpr161 is an A-kinase anchoring protein and the cAMP-sensing Gpr161:PKA complex acts as cilium-compartmentalized signalosome PMID: 27357676
    3. Smoothened determines beta-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. PMID: 27002170
    4. G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion. PMID: 24599592
    5. False positive non-synonymous polymorphisms of G-protein coupled receptor genes. PMID: 11959142

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：

    HGNC: 23694

    OMIM: 612250

    KEGG: hsa:23432

    STRING: 9606.ENSP00000271357

    UniGene: Hs.271809



主站蜘蛛池模板： 精品国产18久久久久久| 国产欧美日本亚洲精品一5区| 亚洲熟妇无码另类久久久| 亚洲精品无码久久久久久| 亚洲一二三四2021不卡| 亚洲一卡一卡二新区无人区| 丰满少妇大叫太大太粗| 国产精品无需播放器在线观看| 国产女人乱人伦精品一区二区 | 中国老妇xxxx性开放| 久久久噜噜噜久久| 欧美人与动欧交视频| 中文天堂在线资源www| 亚洲精品偷拍影视在线观看| 久久久久九九精品影院| 日本少妇高潮喷水视频| 久久天天躁狠狠躁夜夜夜| 天天天天做夜夜夜做| 美女裸体视频永久免费| 亚洲一区在线日韩在线秋葵| 中文字幕乱码免费专区| 亚洲国产精品一区二区www| 国产成人无码精品午夜福利a| 亚洲性无码一区二区三区| h无码精品3d动漫在线观看 | 日韩欧美一区二区三区免费观看| 中文字幕人妻被公上司喝醉在线 | 中日韩产精品1卡二卡三卡| 无套内内射视频网站| 久久久久人妻一区二区三区vr| 久久亚洲日韩av一区二区三区| 奶头好大狂揉60分钟视频| 99在线精品免费视频| 动漫av一区二区在线观看| 人妻系列影片无码专区| 强开小婷嫩苞又嫩又紧视频| 成人做爰100部片免费下载| 琪琪午夜理论片福利在线观看| 欧美一区二区三区| 香港台湾经典三级a视频| 亚洲视频高清不卡在线观看|