在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Claudin-12 (CLDN12)

  • 中文名稱:
    Recombinant Human Claudin-12(CLDN12)
  • 貨號:
    CSB-CF005493HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    CLDN12
  • Uniprot No.:
  • 別名:
    CLDN12; Claudin-12
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-244
  • 氨基酸序列
    MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTVYTGLWVKCAR YDGSSDCLMYDTTWYSSVDQLDLRVLQFALPLSMLIAMGALLLCLIGMCNTAFRSSVPNI KLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWVIFYNIHLNKKFEPVFSFDYAVYVTIA SAGGLFMTSLILFIWYCTCKSLPSPFWQPLYSHPPSMHTYSQPYSARSRLSAIEIDIPVV SHTT
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
  • 基因功能參考文獻:
    1. CLDN 12 expression could be clinically useful for predicting the survival of the estrogen receptor (ER)-negative subgroup of patients with breast cancer. PMID: 26926102
    2. Knockdown of claudin-3, claudin-4, and claudin-12, but not claudin-1, increased breast cancer MCF-7 cell migration with maximal effects observed in claudin-12 siRNA-transfected cells. PMID: 25727011
    3. Differential expression of genes encoding claudins in colorectal cancer suggests that these tight junction proteins may be associated to and involved in tumorigenesis. PMID: 17047970
    4. These findings strongly suggest that claudin-2- and/or claudin-12-based tight junctions form paracellular Ca(2+) channels in intestinal epithelia, and they highlight a novel mechanism behind vitamin D-dependent calcium homeostasis. PMID: 18287530
  • 亞細胞定位:
    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Claudin family
  • 數據庫鏈接:

    HGNC: 2034

    OMIM: 611232

    KEGG: hsa:9069

    STRING: 9606.ENSP00000287916

    UniGene: Hs.731917



主站蜘蛛池模板: 电影内射视频免费观看| 国内精品乱码卡一卡2卡三卡新区 亚洲爆乳成av人在线视菜奈实 | 欧美黑人又粗又大xxx| 国产极品久久久久极品| 亚洲 小说区 图片区 都市| 亚洲国产精品久久久久久| 美女视频黄的全免费视频网站| 免费1级做爰片在线观看爱| 一本大道熟女人妻中文字幕在线| 久久欧美国产伦子伦精品| 久久久久久国产精品美女| 蜜桃av蜜臀av色欲av麻| 熟女性饥渴一区二区三区| 一区二区三区在线 | 欧| 激情毛片无码专区| 毛片免费观看天天干天天爽| 亚洲色素色无码专区| 国产精品人妻一区二区三区四| 日本人妻伦在线中文字幕| 做性久久久久久| 伊人亚洲大杳蕉色无码| 久久精品动漫一区二区三区| 亚洲精品国产综合久久一线| 亚洲欧美日韩国产自偷| 国产老熟女伦老熟妇露脸| 无码精品国产dvd在线观看9久| 欧美xxxxx在线观看| 一边吃奶一边做动态图| 解开人妻的裙子猛烈进入| 国产精品国产三级国产av麻豆| 亚洲高清国产拍精品26u| 欧美浓毛大泬视频| 亚洲国产精品一区第二页| 国产成+人+综合+亚洲 欧美| 国产无吗一区二区三区在线欢| 免费纯肉3d动漫无码网站| 久青草影院在线观看国产| 人妻无码中文专区久久五月婷| 一本一道波多野结衣av一区| 亚洲 欧美 另类图片| 亚洲色国产欧美日韩|