在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Xenopus laevis Protein Wnt-8 (wnt8)

  • 中文名稱:
    有爪蟾蜍wnt8重組蛋白
  • 貨號:
    CSB-YP340936XBE
  • 規格:
    ¥2616
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    wnt8
  • Uniprot No.:
  • 別名:
    wnt8; Protein Wnt-8; XWnt-8
  • 種屬:
    Xenopus laevis (African clawed frog)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    39.7kDa
  • 表達區域:
    23-358aa
  • 氨基酸序列
    AWSVNNFLMTGPKAYLTYSASVAVGAQNGIEECKYQFAWERWNCPESTLQLATHNGLRSATRETSFVHAISSAGVMYTLTRNCSMGDFDNCGCDDSRNGRIGGRGWVWGGCSDNAEFGERISKLFVDGLETGQDARALMNLHNNEAGRLAVKETMKRTCKCHGISGSCSIQTCWLQLAEFRDIGNHLKIKHDQALKLEMDKRKMRSGNSADNRGAIADAFSSVAGSELIFLEDSPDYCLKNISLGLQGTEGRECLQSGKNLSQWERRSCKRLCTDCGLRVEEKKTEIISSCNCKFHWCCTVKCEQCKQVVIKHFCARRERDSNMLNTKRKNRGHRR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in ventral mesodermal patterning during embryogenesis. Mimics Nieuwkoop center activity. Causes dorsal mesodermal differentiation of animal cap ectoderm when coexpressed with noggin and nuclear, sequence-specific DNA-binding protein xBra. None of these molecules causes dorsal mesoderm formation when expressed alone.
  • 基因功能參考文獻:
    1. Data show that Noggin4 fine-tune the Wnt8 posterior-to-anterior gradient. PMID: 26973133
    2. EFHC1 domains are involved in ciliary localization, ciliogenesis, and the regulation of Wnt8a signaling PMID: 26783883
    3. Sulf1 inhibits the ability of Wnt8a to activate the canonical Wnt signalling pathway. PMID: 25681501
    4. study presents the structure of Xenopus Wnt8 (XWnt8) in complex with the mouse Fz8-cysteine-rich domain to a resolution of 3.25 A PMID: 22653731
    5. Xwnt8 directly initiates expression of labial Hox genes. PMID: 19623617
    6. Wnt8 conveyed by Frizzled-related proteins can activate canonical Wnt signalling despite the function of Frizzled-related proteins as Wnt inhibitors, suggesting a novel regulatory system for Wnts by sFRPs PMID: 19906850
    7. by performing gain- and loss-of-function of Wnt signaling experiments, we show that this pathway plays an important role not only in neural crest induction but also in the specification of the neural crest competence territory PMID: 14699582
    8. Wnt8 may stimulate a cellular phosphatase to dephosphorylate and activate CKIepsilon PMID: 14722104
    9. Molecular modeling of the complex between the xWNT8 protein and the CRD domain of mFZD8 PMID: 17506343
    10. Xwnt8-mediated posteriorization is restricted to the eye level and is independent of mesoderm formation. PMID: 18318733
    11. Fgf8a induces neural crest (NC) indirectly through the activation of Wnt8 in the paraxial mesoderm, which in turn promotes NC formation in the overlying ectoderm primed by Bmp antagonists. PMID: 18997112

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Wnt family
  • 數據庫鏈接:

    KEGG: xla:397970

    UniGene: Xl.49



主站蜘蛛池模板: 中日产幕无线码一区| 性少妇中国内射xxxx狠干| 婷婷亚洲综合五月天小说| 成人毛片无码一区二区三区| 中文字幕亚洲色妞精品天堂| 久久久亚洲欧洲日产av| 五月丁香综合缴情六月小说| 国产亚洲精aa在线观看see| 久青草国产在视频在线观看| 337p日本欧洲亚洲大胆在线| 上司的丰满人妻中文字幕| 久久久久国产综合av天堂| 亚洲欧美日韩国产综合v| 国产开嫩苞实拍在线播放视频| 精品国产午夜福利在线观看| 国产激情一区二区三区| 国产精品高清一区二区三区 | 欧美日韩一区二区成人午夜电影| 亚洲精品卡2卡3卡4卡5卡区| 日本一区二区无卡高清视频| 国产精品禁18久久久夂久| 国产普通话对白刺激| 成人性生交大片免费看vr| 182tv午夜福利在线地址二| 鲁鲁夜夜天天综合视频| 久久久久av无码免费网| 亚裔大战黑人老外av| 8av国产精品爽爽ⅴa在线观看| 国语自产免费精品视频在| 无码中文av波多野结衣一区| 在线播放免费人成视频在线观看| 精品久久久久久久久久久国产字幕| 国厂精品114福利电影免费| 99久久伊人精品综合观看| 亚洲国产中文字幕在线视频综合| 人妻另类 专区 欧美 制服| 国产aⅴ爽av久久久久久| 亚洲日本乱码中文在线电影 | 精品日韩亚洲欧美高清a| 久久国产精品成人片免费| 蜜桃无码一区二区三区|